Biocompatibility: Nanomaterials for cell- and tissue engineering

The reaction of cells to varying topographic surfaces has been investigated ever since the beginnings of cell culture technology, as these features influence the cells principle behaviours such as adhesion, spreading, morphology, motility and proliferation. Interest in this aspect of cell biology was renewed when advanced fabrication methods became more widespread. This paper tries to briefly summarise the current state of knowledge regarding the use of nanostructured surfaces for cell- and tissue engineering.

[1]  A S G Curtis,et al.  Fibroblast reaction to island topography: changes in cytoskeleton and morphology with time. , 2003, Biomaterials.

[2]  A. Curtis,et al.  Attempted endocytosis of nano-environment produced by colloidal lithography by human fibroblasts. , 2004, Experimental cell research.

[3]  P WEISS,et al.  Experiments on cell and axon orientation in vitro; the role of colloidal exudates in tissue organization. , 1945, The Journal of experimental zoology.

[4]  C. Wilkinson,et al.  Arrays of nano-dots for cellular engineering , 2003 .

[5]  P. Clark,et al.  Preferential adhesion to and survival on patterned laminin organizes myogenesis in vitro. , 1997, Experimental cell research.

[6]  Matthew J. Dalby,et al.  Cell behaviour of rat calvaria bone cells on surfaces with random nanometric features , 2003 .

[7]  A. Curtis,et al.  Rapid fibroblast adhesion to 27nm high polymer demixed nano-topography. , 2004, Biomaterials.

[8]  A. Cassie,et al.  Wettability of porous surfaces , 1944 .

[9]  C. Wilkinson,et al.  Embossing of nanoscale features and environments , 1997 .

[10]  D. Brunette,et al.  The effects of the surface topography of micromachined titanium substrata on cell behavior in vitro and in vivo. , 1999, Journal of biomechanical engineering.

[11]  Matthew J Dalby,et al.  Fibroblast response to a controlled nanoenvironment produced by colloidal lithography. , 2004, Journal of biomedical materials research. Part A.

[12]  A Curtis,et al.  Guidance and activation of murine macrophages by nanometric scale topography. , 1996, Experimental cell research.

[13]  Uwe Thiele,et al.  Wetting of textured surfaces , 2002 .

[14]  C. Wilkinson,et al.  Nanometric Surface Patterns for Tissue Engineering: Fabrication and Biocompatibility in Vitro , 2001 .

[15]  R. N. Wenzel RESISTANCE OF SOLID SURFACES TO WETTING BY WATER , 1936 .

[16]  M. Riehle,et al.  Interaction of animal cells with ordered nanotopography. , 2002, IEEE transactions on nanobioscience.