Autoimmune comorbidity in achalasia patients

Idiopathic achalasia is a rare esophageal motor disorder. The disease state manifests local and systemic inflammation, and it appears that an autoimmune component and specific autoantibodies participate in the pathogenesis. The study aims to determine the prevalence of autoimmune and chronic inflammatory diseases in patients with achalasia and compare the results with those from patients with gastroesophageal reflux disease (GERD).

[1]  M. Vaezi,et al.  Achalasia: from diagnosis to management , 2016, Annals of the New York Academy of Sciences.

[2]  M. Valdovinos,et al.  New insights into the pathophysiology of achalasia and implications for future treatment , 2016, World journal of gastroenterology.

[3]  M. Frieri,et al.  A link: Allergic rhinitis, Asthma & Systemic Lupus Erythematosus. , 2016, Autoimmunity reviews.

[4]  Cheng-Li Lin,et al.  Epidemiology and risk of juvenile idiopathic arthritis among children with allergic diseases: a nationwide population-based study , 2016, Pediatric Rheumatology.

[5]  James T. Elder,et al.  Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases , 2015, Nature Genetics.

[6]  A. Gamboa-Domínguez,et al.  Achalasia—An Autoimmune Inflammatory Disease: A Cross-Sectional Study , 2015, Journal of immunology research.

[7]  C. Mamillapalli,et al.  Achalasia in a Patient with Polyglandular Autoimmune Syndrome Type II , 2015, Case Reports in Gastroenterology.

[8]  C. Wijmenga,et al.  Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia , 2014, Nature Genetics.

[9]  Torsten Witte,et al.  International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies , 2013, Annals of the rheumatic diseases.

[10]  M. Vaezi.  The American College of Gastroenterology’s New Guidelines on Achalasia: What Clinicians Need to Know , 2013, Current Gastroenterology Reports.

[11]  H. Romdhane,et al.  Circulating antimyenteric autoantibodies in Tunisian patients with idiopathic achalasia. , 2013, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

[12]  J. Pandolfino,et al.  Clinical Guideline : Diagnosis and Management of Achalasia , 2013 .

[13]  Z. Mısırlıgil,et al.  Oesophageal achalasia misdiagnosed as uncontrolled asthma. , 2013, Tuberkuloz ve toraks.

[14]  A. Quidute,et al.  Achalasia and thyroid disease: possible autoimmune connection? , 2012, Arquivos brasileiros de endocrinologia e metabologia.

[15]  M. Laffan,et al.  Severe Recurrent Achalasia Cardia Responding to Treatment of Severe Autoimmune Acquired Haemophilia , 2012, Case Reports in Gastroenterology.

[16]  G. Tomlinson,et al.  The prevalence of autoimmune disease in patients with esophageal achalasia. , 2012, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

[17]  M. Fox,et al.  Chicago classification criteria of esophageal motility disorders defined in high resolution esophageal pressure topography 1 , 2012, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[18]  A. Weetman.  Diseases associated with thyroid autoimmunity: explanations for the expanding spectrum , 2011, Clinical endocrinology.

[19]  F. Ackah,et al.  Achalasia: incidence, prevalence and survival. A population‐based study , 2010, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[20]  G. Farrugia,et al.  Neural Autoantibody Profile of Primary Achalasia , 2010, Digestive Diseases and Sciences.

[21]  Glinda S Cooper,et al.  Recent insights in the epidemiology of autoimmune diseases: improved prevalence estimates and understanding of clustering of diseases. , 2009, Journal of autoimmunity.

[22]  E. Chan,et al.  Clinical interpretation of antinuclear antibody tests in systemic rheumatic diseases , 2009, Modern rheumatology.

[23]  J. Yamamoto-Furusho,et al.  Antinuclear antibodies: A marker associated with steroid dependence in patients with ulcerative colitis , 2008, Inflammatory bowel diseases.

[24]  R. Rabin,et al.  The nexus between atopic disease and autoimmunity: a review of the epidemiological and mechanistic literature ‡ , 2008, Clinical and experimental immunology.

[25]  G. Boeckxstaens.  Achalasia: Virus-Induced Euthanasia of Neurons? , 2008, The American Journal of Gastroenterology.

[26]  P. Brun,et al.  T Cells in the Myenteric Plexus of Achalasia Patients Show a Skewed TCR Repertoire and React to HSV-1 Antigens , 2008, The American Journal of Gastroenterology.

[27]  D. Cocito,et al.  Sensory ataxic neuropathy and esophageal achalasia in a patient with Sjogren's syndrome , 2007, Muscle & nerve.

[28]  H. Daghaghzadeh,et al.  Achalasia and thyroid disease. , 2007, World journal of gastroenterology.

[29]  A. Andriulli,et al.  HLA and enteric antineuronal antibodies in patients with achalasia , 2006, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[30]  D. Alarcón-Segovia,et al.  The different faces of shared autoimmunity. , 2006, Autoimmunity reviews.

[31]  E. Eaker,et al.  Anti-Myenteric Neuronal Antibodies in Patients with Achalasia (A Prospective Study) , 1997, Digestive Diseases and Sciences.

[32]  G. Barbara,et al.  Role of nitric oxide‐ and vasoactive intestinal polypeptide‐containing neurones in human gastric fundus strip relaxations , 2000, British journal of pharmacology.

[33]  M. Topilsky,et al.  Dysphagia with Multiple Autoimmune Disease , 2000, Clinical Rheumatology.

[34]  E. G. de la Concha,et al.  Contribution of HLA class II genes to susceptibility in achalasia. , 1998, Tissue antigens.

[35]  A. Keshavarzian,et al.  Guillain-Barre syndrome and achalasia: two manifestations of a viral disease or coincidental association? , 1994, The American journal of gastroenterology.