Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo
暂无分享,去创建一个
D. Ribatti | S. Zupo | F. Morandi | E. Ognio | I. Airoldi | C. Cocco | E. Carlo | A. Zorzoli | S. Canale | F. Morandi | Claudia Cocco | Fabio Morandi | Irma Airoldi
[1] D. Ribatti,et al. Interleukin-27 inhibits pediatric B-acute lymphoblastic leukemia cell spreading in a preclinical model , 2011, Leukemia.
[2] G. Lenz,et al. Pathogenesis of non-Hodgkin's lymphoma. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[3] F. Morandi,et al. Interleukin‐27 and interleukin‐23 modulate human plasmacell functions , 2011, Journal of leukocyte biology.
[4] Guobin Wang,et al. Th17 cells in cancer: help or hindrance? , 2011, Carcinogenesis.
[5] Andrew Lister,et al. Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial , 2011, The Lancet.
[6] R. Gascoyne,et al. Vascularization predicts overall survival and risk of transformation in follicular lymphoma , 2010, Haematologica.
[7] J. Vose,et al. A Phase 1b/2 trial of mapatumumab in patients with relapsed/refractory non-Hodgkin's lymphoma , 2010, British Journal of Cancer.
[8] D. Ribatti,et al. Interleukin-23 acts as antitumor agent on childhood B-acute lymphoblastic leukemia cells. , 2010, Blood.
[9] R. Gascoyne,et al. Prognostic factors in follicular lymphoma. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[10] S. Zupo,et al. Heterogeneous expression and function of IL-21R and susceptibility to IL-21-mediated apoptosis in follicular lymphoma cells. , 2010, Experimental hematology.
[11] W. Zou,et al. TH17 cells in tumour immunity and immunotherapy , 2010, Nature Reviews Immunology.
[12] S. Paydaş. Anti-angiogenic strategies will be a revolution in lymphoma? , 2010, Leukemia research.
[13] I. Lossos,et al. Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas. , 2010, Blood.
[14] R. Mohammad,et al. New targets for the treatment of follicular lymphoma , 2009, Journal of hematology & oncology.
[15] M. Banerjee,et al. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. , 2009, Blood.
[16] R. D. Hatton,et al. Developmental plasticity of Th17 and Treg cells. , 2009, Current opinion in immunology.
[17] Ganguly Siddhartha,et al. R-CHOP versus R-CVP in the treatment of follicular lymphoma: a meta-analysis and critical appraisal of current literature , 2009, Journal of hematology & oncology.
[18] F. B. Sørensen,et al. Expression level, tissue distribution pattern, and prognostic impact of vascular endothelial growth factors VEGF and VEGF-C and their receptors Flt-1, KDR, and Flt-4 in different subtypes of non-Hodgkin lymphomas , 2009, Leukemia & lymphoma.
[19] D. Ribatti,et al. Constitutive expression of IL-12R beta 2 on human multiple myeloma cells delineates a novel therapeutic target. , 2008, Blood.
[20] B. Aggarwal,et al. Targeting Nuclear Factor-κB Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis , 2008, Molecular Cancer Research.
[21] H. Nagai,et al. Antiproliferative Activity of IL-27 on Melanoma1 , 2008, The Journal of Immunology.
[22] K. Ganjoo,et al. The importance of angiogenesis markers in the outcome of patients with diffuse large B cell lymphoma: a retrospective study of 97 patients , 2008, Journal of Cancer Research and Clinical Oncology.
[23] Dajun Yang,et al. Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model , 2008, Molecular Cancer.
[24] K. Makabe,et al. High IL-21 receptor expression and apoptosis induction by IL-21 in follicular lymphoma. , 2007, Cancer letters.
[25] M. Calaminici,et al. Risk and clinical implications of transformation of follicular lymphoma to diffuse large B-cell lymphoma. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[26] T. Ittel,et al. Rituximab added to first-line mitoxantrone, chlorambucil, and prednisolone chemotherapy followed by interferon maintenance prolongs survival in patients with advanced follicular lymphoma: an East German Study Group Hematology and Oncology Study. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[27] D. Ribatti,et al. Endogenous IL-12 triggers an antiangiogenic program in melanoma cells , 2007, Proceedings of the National Academy of Sciences.
[28] F. B. Sørensen,et al. Angiogenesis in non-Hodgkin's lymphoma: Clinico-pathological correlations and prognostic significance in specific subtypes , 2007, Leukemia & lymphoma.
[29] O. Bairey,et al. Expression of VEGF-C, VEGF-D and their receptor VEGFR-3 in diffuse large B-cell lymphomas , 2007, Leukemia & lymphoma.
[30] M. Caligiuri,et al. A Phase 2 Study of Rituximab in Combination with Recombinant Interleukin-2 for Rituximab-Refractory Indolent Non-Hodgkin's Lymphoma , 2006, Clinical Cancer Research.
[31] S. Miyakis,et al. Serum interleukin-17 and its relationship to angiogenic factors in multiple myeloma. , 2006, European journal of internal medicine.
[32] D. Farkas,et al. Induction of potent antitumor immunity by intratumoral injection of interleukin 23-transduced dendritic cells. , 2006, Cancer research.
[33] T. Mcclanahan,et al. IL-23 promotes tumour incidence and growth , 2006, Nature.
[34] M. Kudo,et al. Antiangiogenic and Antitumor Activities of IL-271 , 2006, The Journal of Immunology.
[35] H. Nagai,et al. Interleukin-23 and interleukin-27 exert quite different antitumor and vaccine effects on poorly immunogenic melanoma. , 2006, Cancer research.
[36] R. Kastelein,et al. Differential Effects of IL-27 on Human B Cell Subsets1 , 2006, The Journal of Immunology.
[37] M. Tagawa,et al. Antitumor activity and immune enhancement of murine interleukin-23 expressed in murine colon carcinoma cells. , 2006, Cellular & molecular immunology.
[38] R. Marcus,et al. CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphoma. , 2005, Blood.
[39] I. Flinn,et al. Phase II Clinical Trial of Interleukin-12 in Patients with Relapsed and Refractory Non-Hodgkin’s Lymphoma and Hodgkin’s Disease , 2004, Clinical Cancer Research.
[40] A. Amadori,et al. The IL-12Rβ2 gene functions as a tumor suppressor in human B cell malignancies , 2004 .
[41] T. Mcclanahan,et al. WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27 , 2004, The Journal of Immunology.
[42] Maria Laura Belladonna,et al. Potent Antitumor Activity of Interleukin-27 , 2004, Cancer Research.
[43] G. Trinchieri,et al. The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. , 2003, Immunity.
[44] Cheng-Wen Wu,et al. Antitumor and Antimetastatic Activity of IL-231 , 2003, The Journal of Immunology.
[45] T. Mcclanahan,et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. , 2002, Immunity.
[46] T. Mcclanahan,et al. A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R1 , 2002, The Journal of Immunology.
[47] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[48] J Wagner,et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. , 2000, Immunity.
[49] R. Levy,et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[50] A Vacca,et al. New model for the study of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane: the gelatin sponge/chorioallantoic membrane assay. , 1997, Journal of vascular research.
[51] M. Andreeff,et al. A pilot study of high-dose interleukin-3 treatment of relapsed follicular small cleaved-cell lymphoma: hematologic, immunologic, and clinical results. , 1996, Blood.
[52] R. Kurzrock,et al. Serum interleukin-6 levels correlate with prognosis in diffuse large-cell lymphoma. , 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[53] R. Mohammad,et al. A unique EBV-negative low-grade lymphoma line (WSU-FSCCL) exhibiting both t(14;18) and t(8;11). , 1993, Cancer genetics and cytogenetics.
[54] T. Lister,et al. Isolated follicular lymphoma cells are resistant to apoptosis and can be grown in vitro in the CD40/stromal cell system. , 1993, Blood.
[55] C. Gisselbrecht,et al. Interleukin-6 production in high-grade B lymphomas: correlation with the presence of malignant immunoblasts in acquired immunodeficiency syndrome and in human immunodeficiency virus-seronegative patients. , 1992, Blood.
[56] Elaine S. Jaffe,et al. evolving concepts and practical applications The 2008 WHO classification of lymphoid neoplasms and beyond , 2011 .
[57] Pierre Biron,et al. Serum cytokines in follicular lymphoma. Correlation of TGF-β and VEGF with survival , 2009, Annals of Hematology.
[58] R. Tibshirani,et al. Prognostic significance of VEGF, VEGF receptors, and microvessel density in diffuse large B cell lymphoma treated with anthracycline-based chemotherapy , 2008, Laboratory Investigation.
[59] J. Raemaekers,et al. Increased vascularization predicts favorable outcome in follicular lymphoma. , 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.