An electron-microscopical study of the postnatal development of the lateral geniculate nucleus in the normal kitten and after eyelid suture

The postnatal development of the lateral geniculate nucleus has been studied qualitatively with the electron microscope in normal kittens and in kittens with unilateral or bilateral eyelid closure. From birth to about 20 days there is relatively little development and the ultrastructural features characteristic of the adult cat, especially the synaptic organization of glomeruli, are mainly acquired between 40 and 55 days, when there is a rapid increase in the level of maturity. Unilateral and bilateral eyelid suture have virtually no effect upon the normal development, but some neurons in the deprived laminae have slightly less granular endoplasmic reticulum.

[1]  R. Kalil.  Development of the dorsal lateral geniculate nucleus in the cat , 1978, The Journal of comparative neurology.

[2]  E. S. Kane,et al.  Development of the dorsal cochlear nucleus of the cat: an electron microscopic study. , 1978, The American journal of anatomy.

[3]  P. D. Spear,et al.  Quantitative studies of cell size in the cat's dorsal lateral geniculate nucleus following visual deprivation , 1977, The Journal of comparative neurology.

[4]  J. Stone,et al.  Properties of relay cells in cat's lateral geniculate nucleus: a comparison of W-cells with X- and Y-cells. , 1976, Journal of neurophysiology.

[5]  T. Powell,et al.  Postnatal development of the synaptic organisation of the lateral geniculate nucleus in the kitten with unilateral eyelid closure , 1976, Nature.

[6]  Jonathan Stone,et al.  Evidence of differential inhibitory influences on X- and Y-type relay cells in the cat's lateral geniculate nucleus , 1976, Brain Research.

[7]  B. Cragg.  The development of synapses in kitten visual cortex during visual deprivation , 1975, Experimental Neurology.

[8]  H. Roffwarg,et al.  The development of unit activity in the lateral geniculate nucleus of the kitten. , 1974, Experimental neurology.

[9]  T. Powell,et al.  Effects of experimental deafferentation on cells in the lateral geniculate nucleus of the cat. , 1973, Brain research.

[10]  J. Stone,et al.  Loss of a specific cell type from dorsal lateral geniculate nucleus in visually deprived cats. , 1972, Journal of neurophysiology.

[11]  E. V. Famiglietti,et al.  The synaptic glomerulus and the intrinsic neuron in the dorsal lateral geniculate nucleus of the cat , 1972, The Journal of comparative neurology.

[12]  T. Powell,et al.  An experimental study of the termination of the lateral geniculo–cortical pathway in the cat and monkey , 1971, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[13]  R. Snider.  Neurobiology of cerebellar evolution and development , 1971 .

[14]  D. Hubel,et al.  The period of susceptibility to the physiological effects of unilateral eye closure in kittens , 1970, The Journal of physiology.

[15]  R. W. Guillery,et al.  A quantitative study of synaptic interconnections in the dorsal lateral geniculate nucleus of the cat , 1969 .

[16]  E. Melby,et al.  Development of fine structure of spinal cord in monkey fetuses. II. Pre‐reflex period to period of long intersegmental reflexes , 1968 .

[17]  R W Guillery,et al.  A study of Golgi preparations from the dorsal lateral geniculate nucleus of the adult cat , 1966, The Journal of comparative neurology.

[18]  A. Peters,et al.  The morphology of laminae A and A1 of the dorsal nucleus of the lateral geniculate body of the cat. , 1966, Journal of anatomy.

[19]  D. Hubel,et al.  SINGLE-CELL RESPONSES IN STRIATE CORTEX OF KITTENS DEPRIVED OF VISION IN ONE EYE. , 1963, Journal of neurophysiology.

[20]  D. Hubel,et al.  EFFECTS OF VISUAL DEPRIVATION ON MORPHOLOGY AND PHYSIOLOGY OF CELLS IN THE CATS LATERAL GENICULATE BODY. , 1963, Journal of neurophysiology.

[21]  E. Reynolds.  THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY , 1963, The Journal of cell biology.

[22]  H. Hirsch.  Chapter 4 – The Perfectible Brain: Principles of Neuronal Development , 1975 .

[23]  R W Guillery,et al.  Patterns of synaptic interconnections in the dorsal lateral geniculate nucleus of cat and monkey: a brief review. , 1971, Vision research.

[24]  J. Szentágothai.  THE STRUCTURE OF THE SYNAPSE IN THE LATERAL GENICULATE BODY. , 1963, Acta anatomica.

[25]  K. C. Richardson,et al.  Embedding in epoxy resins for ultrathin sectioning in electron microscopy. , 1960, Stain technology.