Assessment of Temporal Resolution in Multiple Sclerosis by Multi-Flash Campimetry

There is good evidence that some of the major effects of multiple sclerosis (MS) involve deficits in the temporal responses of the visual system. Naturally, several different psychophysical and electrophysiological methods have been developed for assessing temporal sensitivity in visual disorders. Such tests include, for example, tests of delayed visual perception such as apparent simultaneity matches [1], critical fusion frequency for flashing lights [2,3,4], Pulfrich effect tests [5], and measurements of the latencies of visual evoked potentials [6,7,8]. We believe that one of the most useful measures of temporal resolution is the double-flash discrimination test that has been developed by REGAN and others [9,10,11].