Diagnosis of patent ductus arteriosus by a neonatologist with a compact, portable ultrasound machine

Objectives:To conduct a pilot study assessing a neonatologist's accuracy in diagnosing patent ductus arteriosus (PDA) using compact, portable ultrasound after limited training.Study design:Prospective study of premature infants scheduled for echocardiography for suspected PDA. A neonatologist with limited training performed study exams before scheduled exams. Sensitivity and specificity were calculated, compared to the scheduled echocardiogram interpreted by a cardiologist.Results:There were 24 exams. Compared to the scheduled exam, the neonatologist's exam had sensitivity 69% (95% confidence interval (CI), 41 to 89%) and specificity 88% (95% CI, 47 to 99%). When a cardiologist interpreted the study exams, the sensitivity was 87% (95% CI, 60 to 98%) and specificity 71% (95% CI, 29 to 96%).Conclusion:A neonatologist with limited training was able to detect PDA with moderate success. A more rigorous training process or real-time transmission with cardiologist interpretation may substantially improve accuracy. Institutions with experienced technicians and on-site pediatric cardiologists may not gain from intensive training of neonatologists, but hospitals where diagnosis and treatment of PDA would be delayed may benefit from such processes.

[1]  S. Chida,et al.  Cardiocirculatory effects of patent ductus arteriosus in extremely low‐birth‐weight infants with respiratory distress syndrome , 2003, Pediatrics international : official journal of the Japan Pediatric Society.

[2]  P. Davis,et al.  Precision and accuracy of clinical and radiological signs in premature infants at risk of patent ductus arteriosus. , 1995, Archives of pediatrics & adolescent medicine.

[3]  N. Evans,et al.  A blinded comparison of clinical and echocardiographic evaluation of the preterm infant for patent ductus arteriosus , 1994, Journal of paediatrics and child health.

[4]  Neil Marlow,et al.  The EPICure Study: Outcomes to Discharge From Hospital for Infants Born at the Threshold of Viability , 2000, Pediatrics.

[5]  Craig A Sable,et al.  Impact of telemedicine on the practice of pediatric cardiology in community hospitals. , 2002, Pediatrics.

[6]  B. Siassi,et al.  Mechanics of Breathing after Surgical Ligation of Patent Ductus arteriosus in Newborns with Respiratory Distress Syndrome , 2004, Neonatology.

[7]  W. Duvall,et al.  Can Hand‐Carried Ultrasound Devices be Extended for Use by the Noncardiology Medical Community? , 2003, Echocardiography.

[8]  Walter Chen,et al.  Clinical analysis of necrotizing enterocolitis with intestinal perforation in premature infants. , 2002, Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi.

[9]  W. Brant,et al.  Emergency department ultrasonography in the evaluation of hypotensive and normotensive children with blunt abdominal trauma. , 2001, Journal of pediatric surgery.

[10]  A. Brooks,et al.  Prospective evaluation of non-radiologist performed emergency abdominal ultrasound for haemoperitoneum , 2004, Emergency Medicine Journal.

[11]  Xiaokui Li,et al.  Will a handheld ultrasound scanner be applicable for screening for heart abnormalities in newborns and children? , 2003, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[12]  Suresh Kumar,et al.  A study of congenital cardiac disease in a neonatal population – the validity of echocardiography undertaken by a neonatologist , 2004, Cardiology in the Young.

[13]  T. Naqvi,et al.  Usefulness of a hand-carried cardiac ultrasound device to detect clinically significant valvular regurgitation in hospitalized patients. , 2004, The American journal of cardiology.

[14]  A. Shalabi,et al.  Incidence and risk factors associated with the patency of ductus arteriosus in preterm infants with respiratory distress syndrome in Kuwait. , 2003, Saudi Medical Journal.

[15]  C. Peng,et al.  Risk factors of pulmonary hemorrhage in very-low-birth-weight infants: a two-year retrospective study. , 2000, Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi.

[16]  Andrew W Kirkpatrick,et al.  The hand-held FAST: experience with hand-held trauma sonography in a level-I urban trauma center. , 2002, Injury.

[17]  C. Romagnoli,et al.  Early changes of pulmonary mechanics to predict the severity of bronchopulmonary dysplasia in ventilated preterm infants , 2002, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

[18]  K. Costigan,et al.  Interpretation of biophysical profiles by nurses and physicians. , 1994, Journal of obstetric, gynecologic, and neonatal nursing : JOGNN.

[19]  F. Macartney,et al.  Suprasternal cross-sectional echocardiography in assessment of patient ducts arteriosus. , 1982, British heart journal.

[20]  N. Evans,et al.  Early ductal shunting and intraventricular haemorrhage in ventilated preterm infants. , 1996, Archives of disease in childhood. Fetal and neonatal edition.

[21]  M. Argyropoulou,et al.  MRI measurements of the pons and cerebellum in children born preterm; associations with the severity of periventricular leukomalacia and perinatal risk factors , 2003, Neuroradiology.

[22]  M. Hack,et al.  Placental and Other Perinatal Risk Factors for Chronic Lung Disease in Very Low Birth Weight Infants , 2002, Pediatric Research.

[23]  J. Skinner Echocardiography on the neonatal unit: a job for the neonatologist or the cardiologist? , 1998, Archives of disease in childhood.

[24]  D. Urquhart,et al.  How good is clinical examination at detecting a significant patent ductus arteriosus in the preterm neonate? , 2003, Archives of disease in childhood.