Determination of lipophilic descriptors of antihelmintic 6,7-diaryl-pteridine derivatives useful for bioactivity predictions.
暂无分享,去创建一个
J. Silber | C. Ochoa | M. Santo | M. Reta | L. Giacomelli | R. Cattana | Mercedes Rodriguez | A. Chana
[1] C. Poole,et al. Retention characteristics of an immobilized artificial membrane column in reversed-phase liquid chromatography. , 2002, Journal of chromatography. A.
[2] B. Smart. Fluorine substituent effects (on bioactivity) , 2001 .
[3] U. Norinder,et al. The applicability of computational chemistry in the evaluation and prediction of drug transport properties , 2000 .
[4] M. Abraham,et al. Rapid-gradient HPLC method for measuring drug interactions with immobilized artificial membrane: comparison with other lipophilicity measures. , 2000, Journal of pharmaceutical sciences.
[5] R. Kaliszan,et al. Retention of barbituric acid derivatives on immobilized artificial membrane stationary phase and its correlation with biological activity. , 2000, Biomedical chromatography : BMC.
[6] J. Silber,et al. Role of Weak Molecular Interactions in the Mechanism of Action of a Series of Antihelmintics , 2000 .
[7] S. Goldstein,et al. IAM retention and blood brain barrier penetration , 1998 .
[8] G. Caldwell,et al. Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions. , 1998, Journal of chromatography. A.
[9] M. Abraham,et al. Relationships between the chromatographic hydrophobicity indices and solute descriptors obtained by using several reversed-phase, diol, nitrile, cyclodextrin and immobilised artificial membrane-bonded high-performance liquid chromatography columns , 1998 .
[10] M. L. La Rotonda,et al. Interactions of nonsteroidal antiinflammatory drugs with phospholipids: comparison between octanol/buffer partition coefficients and chromatographic indexes on immobilized artificial membranes. , 1997, Journal of pharmaceutical sciences.
[11] C. Pidgeon,et al. Predicting drug-membrane interactions by HPLC: structural requirements of chromatographic surfaces. , 1995, Analytical chemistry.
[12] J. Silber,et al. Competition between inter- and intramolecular hydrogen bonding in molecules with donor and acceptor groups. Solvatochromic and thermochromic evidence in n-(nitrophenyl)alkylenediamines , 1994 .
[13] Lloyd R. Snyder,et al. Retention in reversed-phase liquid chromatography as a function of mobile-phase composition , 1993 .
[14] W. J. Lambert. Modeling oil-water partitioning and membrane permeation using reversed-phase chromatography , 1993 .
[15] M. Khaledi,et al. Hydrophobicity estimations by reversed-phase liquid chromatography. Implications for biological partitioning processes. , 1993, Journal of chromatography.
[16] J. Dorsey,et al. Accurate determination of log k'w in reversed-phase liquid chromatography. Implications for quantitative structure-retention relationships. , 1993, Journal of chromatography.
[17] Gerald J. Niemi,et al. Optimal characterization of structure for prediction of properties , 1990 .
[18] J. Dorsey,et al. Estimation of the reversed-phase liquid chromatographic lipophilicity parameter log k'w using ET-30 solvatochromism. , 1990, Journal of chromatography.
[19] M. Stud,et al. High-Performance Liquid Chromatography of 1, 2, 6-Thiadiazinone 1, 1-Dioxides and Related Pyrazolones: A Comparative Study of Hydrophobicity , 1988 .
[20] J. Legendre,et al. Factors governing the retention of solutes on chromatographic immobilized artificial membranes : Application to anti-inflammatory and analgesic drugs , 1999 .
[21] Ana Martínez,et al. Comparative Molecular Field Analysis (CoMFA) on [6] + [6] Fused Pyrazines with Nematocide Properties , 1997 .
[22] F. Quaglia,et al. Chromatographic indices determined on an immobilized artificial membrane (IAM) column as descriptors of lipophilic and polar interactions of 4-phenyldihydropyridine calcium-channel blockers with biomembranes† , 1996 .
[23] J. Dorsey,et al. Bioavailability estimation by reversed-phase liquid chromatography: high bonding density C-18 phases for modeling biopartitioning processes. , 1995, Analytical chemistry.
[24] C. Foces-Foces,et al. Tautomerism in Pyrazino[2,3-c]-1,2,6-thiadiazine 2,2-Dioxides , 1988 .