A simple method for repeated sampling of lumbar cerebrospinal fluid in goats

A technique has been developed for repeated sampling of cerebrospinal fluid from conscious goats by means of a catheter placed surgically in the subarachnoid space between the sixth and seventh lumbar vertebrae. Uncontaminated cerebrospinal fluid in excess of 1.0 ml could be obtained readily from the cannulated goats several times daily for up to 6 weeks. Cannulated goats did not appear stressed during, and in between, sampling periods.

[1]  W. H. Harris.  Duke's Physiology of Domestic Animals, 11th ed , 1994 .

[2]  B. Brewer.  Examination of the bovine nervous system. , 1987, The Veterinary clinics of North America. Food animal practice.

[3]  R. Smith,et al.  Cannulation of the cisterna magna in sheep: a method for chronic studies of cerebrospinal fluid. , 1985, The Australian journal of experimental biology and medical science.

[4]  W. F. Braun,et al.  Serum and cerebrospinal fluid concentrations of immunoglobulin G in Suffolk sheep with scrapie. , 1984, American journal of veterinary research.

[5]  L. Hedlund,et al.  Cerebral ventricle cannulation in the calf. , 1977, Journal of dairy science.

[6]  J. Bligh,et al.  Electrolyte concentrations in sheep cerebrospinal fluid. , 1977, Research in Veterinary Science.

[7]  Mayhew Ig.  Collection of cerebrospinal fluid from the horse. , 1975 .

[8]  J. Pappenheimer,et al.  Perfusion of the cerebral ventricular system in unanesthetized goats , 1962 .

[9]  H. Merritt,et al.  The cerebrospinal fluid , 1935 .

[10]  A. Peregrine,et al.  Relapse of Trypanosoma congolense infection in goats after diminazene aceturate is not a result of invasion of the central nervous system. , 1994, Annals of tropical medicine and parasitology.

[11]  T. Allsop,et al.  Magnesium concentrations in the ventricular and lumbar cerebrospinal fluid of hypomagnesaemic cows. , 1985, Research in veterinary science.

[12]  I. Mayhew.  Collection of cerebrospinal fluid from the horse. , 1975, The Cornell veterinarian.