Senile changes of the human testis from 121 autopsy cases were histologically examined in 6 topographic parts which were divided by the microangiography, and the findings were discussed in relation to blood supply. Focal depletion of spermiogenesis with thickening of the basement membrane of seminiferous tubules appeared in the fourth and fifth decades and pigmentation of the interstitial cells later. The senile changes were not uniform in severity throughout the testis and were induced in a distribution pattern with a close relation to blood supply. Main arteries of the testis descended along the medial surface to the lower pole and turned up along the lateral surface to the upper pole. On the upward way the main arteries extended branches toward the mediastinum. Therefore, the upper pole and the posterior part adjacent to the mediastinum belonged to the distal area in the arterial supply and showed advanced senile changes in general. Hernia-like protrusions, however, were prevalent in the lower and anterior parts proximal to the arterial trunk.
[1]
S. Hatakeyama.
On the hernia-like protrusions suggestive of regeneration of the human seminiferous tubule.
,
1962
.
[2]
W. Scott,et al.
The lipid content of the Leydig cell and Sertoli cell in the human testis as related to age, benign prostatic hyperplasia, and prostatic cancer.
,
1950,
The Journal of urology.
[3]
R. C. Sniffen.
THE TESTES. I THE NORMAL TESTIS
,
1950
.
[4]
F. A. Simmons,et al.
The testis. II. Abnormalities of spermatogenesis; atresia of the excretory ducts.
,
1950,
Archives of pathology.
[5]
R. C. Sniffen.
The testis. I. The normal testis.
,
1950,
Archives of pathology.
[6]
R. Harrison,et al.
The distribution of the testicular artery (internal spermatic artery) to the human testis.
,
1948,
British journal of urology.