Effects of thiamine and fenofibrate on high glucose and hypoxia-induced damage in cell models of the inner blood-retinal barrier
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M. Porta | Chiara Gai | M. Trento | E. Beltramo | A. Mazzeo
[1] I. Čavar,et al. Concentrations of Selected Cytokines and Vascular Endothelial Growth Factor in Aqueous Humor and Serum of Diabetic Patients , 2020, Seminars in ophthalmology.
[2] M. Porta,et al. Thiamine transporter 2 is involved in high glucose-induced damage and altered thiamine availability in cell models of diabetic retinopathy , 2019, Diabetes & vascular disease research.
[3] A. Caccuri,et al. Activation of retinal Müller cells in response to glucose variability , 2019, Endocrine.
[4] M. Porta,et al. Functional analysis of miR-21-3p, miR-30b-5p and miR-150-5p shuttled by extracellular vesicles from diabetic subjects reveals their association with diabetic retinopathy. , 2019, Experimental eye research.
[5] M. S. Sajib,et al. Role of Angiopoietin-2 in Vascular Physiology and Pathophysiology , 2019, Cells.
[6] N. Luo,et al. Association between ICAM-1 level and diabetic retinopathy: a review and meta-analysis , 2019, Postgraduate Medical Journal.
[7] A. Keech,et al. Fenofibrate Rescues Diabetes-Related Impairment of Ischemia-Mediated Angiogenesis by PPARα-Independent Modulation of Thioredoxin-Interacting Protein , 2019, Diabetes.
[8] N. Lois,et al. Fenofibrate for Diabetic Retinopathy , 2018, Asia-Pacific journal of ophthalmology.
[9] Grazia Maugeri,et al. NAP counteracts hyperglycemia/hypoxia induced retinal pigment epithelial barrier breakdown through modulation of HIFs and VEGF expression , 2018, Journal of cellular physiology.
[10] A. Miyamoto,et al. Beyond the Matrix: The Many Non-ECM Ligands for Integrins , 2018, International journal of molecular sciences.
[11] S. Mohr,et al. Müller cells and diabetic retinopathy , 2017, Vision Research.
[12] Haitao Shen,et al. Role of the PKCβII/JNK signaling pathway in acute glucose fluctuation-induced apoptosis of rat vascular endothelial cells , 2017, Acta Diabetologica.
[13] Á. Valverde,et al. Modulation of microglia in the retina: new insights into diabetic retinopathy , 2017, Acta Diabetologica.
[14] P. Pasqualetti,et al. Retinal neurodegeneration in patients with type 1 diabetes mellitus: the role of glycemic variability , 2017, Acta Diabetologica.
[15] Alison L. Reynolds,et al. Phenotype-based Discovery of 2-[(E)-2-(Quinolin-2-yl)vinyl]phenol as a Novel Regulator of Ocular Angiogenesis* , 2016, The Journal of Biological Chemistry.
[16] R. Simó,et al. Fenofibrate prevents the disruption of the outer blood retinal barrier through downregulation of NF-κB activity , 2016, Acta Diabetologica.
[17] A. Paterson,et al. Variation in SLC19A3 and Protection From Microvascular Damage in Type 1 Diabetes , 2015, Diabetes.
[18] R. Simó,et al. Beneficial effects of fenofibric acid on overexpression of extracellular matrix components, COX-2, and impairment of endothelial permeability associated with diabetic retinopathy. , 2015, Experimental eye research.
[19] K. Alitalo,et al. Endothelial destabilization by angiopoietin-2 via integrin β1 activation , 2015, Nature Communications.
[20] M. Porta,et al. Extracellular vesicles derived from mesenchymal stem cells induce features of diabetic retinopathy in vitro , 2014, Acta Diabetologica.
[21] Elena Beltramo,et al. Pericyte loss in diabetic retinopathy: mechanisms and consequences. , 2013, Current medicinal chemistry.
[22] Jason Zastre,et al. HIF1-α-mediated gene expression induced by vitamin B1 deficiency. , 2013, International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
[23] S. Abcouwer. Direct Effects of PPARα Agonists on Retinal Inflammation and Angiogenesis May Explain How Fenofibrate Lowers Risk of Severe Proliferative Diabetic Retinopathy , 2012, Diabetes.
[24] A. Keech,et al. Therapeutic Effects of PPARα Agonists on Diabetic Retinopathy in Type 1 Diabetes Models , 2012, Diabetes.
[25] Philippe Soriano,et al. PDGFRβ signaling regulates mural cell plasticity and inhibits fat development. , 2011, Developmental cell.
[26] R. Bischoff,et al. Physiology and pathophysiology of matrix metalloproteases , 2010, Amino Acids.
[27] Walter T Ambrosius,et al. Effects of medical therapies on retinopathy progression in type 2 diabetes. , 2010, The New England journal of medicine.
[28] Elena Berrone,et al. Effects of high glucose and thiamine on the balance between matrix metalloproteinases and their tissue inhibitors in vascular cells , 2010, Acta Diabetologica.
[29] Elena Berrone,et al. Thiamine and benfotiamine prevent apoptosis induced by high glucose‐conditioned extracellular matrix in human retinal pericytes , 2009, Diabetes/metabolism research and reviews.
[30] Elena Berrone,et al. Different apoptotic responses of human and bovine pericytes to fluctuating glucose levels and protective role of thiamine , 2009, Diabetes/metabolism research and reviews.
[31] H. Hammes,et al. Establishment and characterization of a human retinal pericyte line: a novel tool for the study of diabetic retinopathy. , 2009, International journal of molecular medicine.
[32] M. Porta,et al. Effects of thiamine and benfotiamine on intracellular glucose metabolism and relevance in the prevention of diabetic complications , 2008, Acta Diabetologica.
[33] P. Mitchell,et al. Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial , 2007, The Lancet.
[34] R. Babaei-Jadidi,et al. High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease , 2007, Diabetologia.
[35] Elena Berrone,et al. Regulation of Intracellular Glucose and Polyol Pathway by Thiamine and Benfotiamine in Vascular Cells Cultured in High Glucose* , 2006, Journal of Biological Chemistry.
[36] C. Betsholtz,et al. Endothelial/Pericyte Interactions , 2005, Circulation research.
[37] H. Hammes,et al. Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy. , 2004, Diabetes.
[38] MarkusMeissner,et al. PPARα Activators Inhibit Vascular Endothelial Growth Factor Receptor-2 Expression by Repressing Sp1-Dependent DNA Binding and Transactivation , 2004 .
[39] C. Urbich,et al. PPAR&agr; Activators Inhibit Vascular Endothelial Growth Factor Receptor-2 Expression by Repressing Sp1-Dependent DNA Binding and Transactivation , 2004, Circulation research.
[40] L. Metheny-Barlow,et al. The enigmatic role of angiopoietin-1 in tumor angiogenesis , 2003, Cell Research.
[41] R. Babaei-Jadidi,et al. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. , 2003, Diabetes.
[42] H. Hammes,et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy , 2003, Nature Medicine.
[43] G. A. Limb,et al. Differential expression of matrix metalloproteinases 2 and 9 by glial Müller cells: response to soluble and extracellular matrix-bound tumor necrosis factor-alpha. , 2002, The American journal of pathology.
[44] G. A. Limb,et al. In vitro characterization of a spontaneously immortalized human Müller cell line (MIO-M1). , 2002, Investigative ophthalmology & visual science.
[45] K. Kashiwagi,et al. MATRIX METALLOPROTEINASES IN HUMAN DIABETIC AND NONDIABETIC VITREOUS , 2001, Retina.
[46] T. Nishikawa,et al. The missing link: a single unifying mechanism for diabetic complications. , 2000, Kidney international. Supplement.
[47] K. Suzuma,et al. Hypoxia and Vascular Endothelial Growth Factor Selectively Up-regulate Angiopoietin-2 in Bovine Microvascular Endothelial Cells* , 1999, The Journal of Biological Chemistry.
[48] M. Porta,et al. Thiamine corrects delayed replication and decreases production of lactate and advanced glycation end-products in bovine retinal and human umbilical vein endothelial cells cultured under high glucose conditions , 1996, Diabetologia.