Synchronizing Hindmarsh-Rose neurons over Newman-Watts networks.

In this paper, the synchronization behavior of the Hindmarsh-Rose neuron model over Newman-Watts networks is investigated. The uniform synchronizing coupling strength is determined through both numerically solving the network's differential equations and the master-stability-function method. As the average degree is increased, the gap between the global synchronizing coupling strength, i.e., the one obtained through the numerical analysis, and the strength necessary for the local stability of the synchronization manifold, i.e., the one obtained through the master-stability-function approach, increases. We also find that this gap is independent of network size, at least in a class of networks considered in this work. Limiting the analysis to the master-stability-function formalism for large networks, we find that in those networks with size much larger than the average degree, the synchronizing coupling strength has a power-law relation with the shortcut probability of the Newman-Watts network. The synchronization behavior of the network of nonidentical Hindmarsh-Rose neurons is investigated by numerically solving the equations and tracking the average synchronization error. The synchronization of identical Hindmarsh-Rose neurons coupled over clustered Newman-Watts networks, networks with dense intercluster connections but sparsely in intracluster linkage, is also addressed. It is found that the synchronizing coupling strength is influenced mainly by the probability of intercluster connections with a power-law relation. We also investigate the complementary role of chemical coupling in providing complete synchronization through electrical connections.

[1]  Martin Hasler,et al.  Synchronization of bursting neurons: what matters in the network topology. , 2005, Physical review letters.

[2]  W. Singer,et al.  Long-range synchronization of oscillatory light responses in the cat retina and lateral geniculate nucleus , 1996, Nature.

[3]  K. Nakajima,et al.  Bursting characteristics of a neuron model based on a concept of potential with active areas. , 2008, Chaos.

[4]  Wolf Singer,et al.  Neuronal Synchrony: A Versatile Code for the Definition of Relations? , 1999, Neuron.

[5]  Alessandro Torcini,et al.  Dynamical phases of the Hindmarsh-Rose neuronal model: studies of the transition from bursting to spiking chaos. , 2007, Chaos.

[6]  R. Dzakpasu,et al.  Discriminating differing types of synchrony in neural systems , 2005 .

[7]  L F Lago-Fernández,et al.  Fast response and temporal coherent oscillations in small-world networks. , 1999, Physical review letters.

[8]  Jurgen Kurths,et al.  Synchronization in complex networks , 2008, 0805.2976.

[9]  Olaf Sporns,et al.  The small world of the cerebral cortex , 2007, Neuroinformatics.

[10]  M. Newman,et al.  Mean-field solution of the small-world network model. , 1999, Physical review letters.

[11]  A. Hodgkin,et al.  A quantitative description of membrane current and its application to conduction and excitation in nerve , 1952, The Journal of physiology.

[12]  B. Ermentrout,et al.  Chemical and electrical synapses perform complementary roles in the synchronization of interneuronal networks. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[13]  J. Hindmarsh,et al.  A model of neuronal bursting using three coupled first order differential equations , 1984, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[14]  M. Newman,et al.  Renormalization Group Analysis of the Small-World Network Model , 1999, cond-mat/9903357.

[15]  Olaf Sporns,et al.  The Human Connectome: A Structural Description of the Human Brain , 2005, PLoS Comput. Biol..

[16]  C. Stam,et al.  Small-world networks and functional connectivity in Alzheimer's disease. , 2006, Cerebral cortex.

[17]  B. Connors,et al.  A network of electrically coupled interneurons drives synchronized inhibition in neocortex , 2000, Nature Neuroscience.

[18]  W. Singer,et al.  Oscillatory responses in cat visual cortex exhibit inter-columnar synchronization which reflects global stimulus properties , 1989, Nature.

[19]  C. Stam,et al.  Small-world network organization of functional connectivity of EEG slow-wave activity during sleep , 2007, Clinical Neurophysiology.

[20]  Duncan J. Watts,et al.  Collective dynamics of ‘small-world’ networks , 1998, Nature.

[21]  P. Somogyi,et al.  Proximally targeted GABAergic synapses and gap junctions synchronize cortical interneurons , 2000, Nature Neuroscience.

[22]  Eugene M. Izhikevich,et al.  Which model to use for cortical spiking neurons? , 2004, IEEE Transactions on Neural Networks.

[23]  C. Stam,et al.  Small-world networks and disturbed functional connectivity in schizophrenia , 2006, Schizophrenia Research.

[24]  L. Glass Synchronization and rhythmic processes in physiology , 2001, Nature.

[25]  M E J Newman,et al.  Community structure in social and biological networks , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[26]  O. Sporns Small-world connectivity, motif composition, and complexity of fractal neuronal connections. , 2006, Bio Systems.

[27]  Mahdi Jalili,et al.  Enhancing synchronizability of dynamical networks using the connection graph stability method , 2007, Int. J. Circuit Theory Appl..

[28]  Adilson E Motter,et al.  Heterogeneity in oscillator networks: are smaller worlds easier to synchronize? , 2003, Physical review letters.

[29]  Mauricio Barahona,et al.  Synchronization in small-world systems. , 2002, Physical review letters.

[30]  Reto Meuli,et al.  Dysconnection Topography in Schizophrenia Revealed with State-Space Analysis of EEG , 2007, PloS one.

[31]  O. Sporns,et al.  Organization, development and function of complex brain networks , 2004, Trends in Cognitive Sciences.

[32]  Nancy Kopell,et al.  Rapid synchronization through fast threshold modulation , 1993, Biological Cybernetics.

[33]  R. Traub,et al.  Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro , 1998, Nature.

[34]  G. Buzsáki Rhythms of the brain , 2006 .

[35]  Y. Lai,et al.  Abnormal synchronization in complex clustered networks. , 2006, Physical review letters.

[36]  P. Skudlarski,et al.  Nicotine effects on brain function and functional connectivity in schizophrenia , 2004, Biological Psychiatry.

[37]  Enno de Lange,et al.  The Hindmarsh-Rose neuron model: bifurcation analysis and piecewise-linear approximations. , 2008, Chaos.

[38]  M. Hasler,et al.  Connection Graph Stability Method for Synchronized Coupled Chaotic Systems , 2004 .

[39]  Duncan J. Watts,et al.  Six Degrees: The Science of a Connected Age , 2003 .

[40]  T. Prescott,et al.  The brainstem reticular formation is a small-world, not scale-free, network , 2006, Proceedings of the Royal Society B: Biological Sciences.

[41]  W. Singer,et al.  Neural Synchrony in Brain Disorders: Relevance for Cognitive Dysfunctions and Pathophysiology , 2006, Neuron.

[42]  Mark E. J. Newman,et al.  The Structure and Function of Complex Networks , 2003, SIAM Rev..

[43]  Thomas Nowotny,et al.  Neuronal synchrony: peculiarity and generality. , 2008, Chaos.

[44]  F T Arecchi,et al.  Comparison of single neuron models in terms of synchronization propensity. , 2008, Chaos.

[45]  Changsong Zhou,et al.  Hierarchical organization unveiled by functional connectivity in complex brain networks. , 2006, Physical review letters.

[46]  T. Carroll,et al.  Master Stability Functions for Synchronized Coupled Systems , 1998 .

[47]  B. Connors,et al.  Two networks of electrically coupled inhibitory neurons in neocortex , 1999, Nature.