Laser-assisted In Situ Keratomileusis for Correction of Astigmatism and Increasing Contact Lens Tolerance after Penetrating Keratoplasty

Purpose To determine effectiveness of laser-assisted in situ keratomileusis (LASIK) in the treatment of astigmatism following penetrating keratoplasty (PK). Methods We performed a retrospective review of medical records of patients who underwent LASIK following PK and had over 1 year of follow-up data. Results Twenty-six patients (26 pairs of eyes) underwent LASIK following PK. Mean age of the patients at the time of LASIK was 40.7 years (range, 26 to 72 years). Following LASIK, the mean cylinder was reduced by 2.4 diopters and mean reduction of cylinder after LASIK was 65.4% from the preoperative values at the last follow-up visit. Uncorrected visual acuity became 20 / 50 or better in 69.2% of the eyes after LASIK. Best-corrected visual acuity became 20 / 50 or better in 73.1% of the eyes after LASIK. All of them were intolerable to contact lenses before LASIK. After LASIK, 6 pairs (23.1%) did not need to use contact lenses and 18 pairs (69.2%) were tolerable to using contact lenses or spectacles. There were no significant endothelial cell density changes 12 months after LASIK (p = 0.239). Conclusions LASIK is effective in the treatment of astigmatism following PK and increases contact lens and spectacle tolerance.

[1]  T. Kohnen,et al.  Corneal first‐surface aberration analysis of the biomechanical effects of astigmatic keratotomy and a microkeratome cut after penetrating keratoplasty , 2005, Journal of cataract and refractive surgery.

[2]  J. Alió,et al.  Laser in situ keratomileusis to correct post‐keratoplasty astigmatism: 1‐step versus 2‐step procedure , 2004, Journal of cataract and refractive surgery.

[3]  R. Lindstrom,et al.  Long term analysis of LASIK for the correction of refractive errors after penetrating keratoplasty. , 2004, Cornea.

[4]  S. McLeod,et al.  Wound dehiscence in a patient with keratoconus after penetrating keratoplasty and LASIK. , 2004, Archives of ophthalmology.

[5]  J. Febbraro,et al.  Laser in situ keratomileusis for the correction of residual ametropia after penetrating keratoplasty , 2004, Journal of cataract and refractive surgery.

[6]  C. C.,et al.  Five-Year Results of Laser In-Situ Keratomileusis (LASIK) After Penetrating Keratoplasty , 2004, Cornea.

[7]  D. Albert,et al.  Pocket of fluid in the lamellar interface after penetrating keratoplasty and laser in situ keratomileusis. , 2003, Archives of ophthalmology.

[8]  Ş. Özdek,et al.  Photorefractive keratectomy for post‐penetrating keratoplasty myopia and astigmatism , 2000, Journal of cataract and refractive surgery.

[9]  A. Bansal Photoastigmatic refractive keratectomy for correction of astigmatism after keratoplasty. , 1999, Journal of refractive surgery.

[10]  B. Glasgow,et al.  Corneal scarring after photorefractive keratectomy in a penetrating keratoplasty. , 1996, American journal of ophthalmology-glaucoma.

[11]  I. Aslanides,et al.  Excmier Laser Keratectomy for Astigmatism Occurring after Penetrating Keratoplasty , 1996 .

[12]  I. Aslanides,et al.  Excimer laser keratectomy for astigmatism occurring after penetrating keratoplasty. , 1996, Ophthalmology.

[13]  B. Koffler,et al.  A new contact lens design for post-keratoplasty patients. , 1994, The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc.

[14]  J. Garbus,et al.  Photorefractive keratectomy for severe postkeratoplasty astigmatism. , 1992, American journal of ophthalmology.

[15]  S. Macrae,et al.  The effect of hard contact lens wear on the keratoconic corneal endothelium after penetrating keratoplasty. , 1989, American journal of ophthalmology.

[16]  K. Zadnik,et al.  Fitting gas-permeable contact lenses after penetrating keratoplasty. , 1985, American journal of ophthalmology.