Enhancing the stability, BBB permeability and neuroprotective activity of verbascoside in vitro using lipid nanocapsules in combination with menthol.

[1]  Hong-mei An,et al.  Acteoside and ursolic acid synergistically protects H2O2-induced neurotrosis by regulation of AKT/mTOR signalling: from network pharmacology to experimental validation , 2022, Pharmaceutical biology.

[2]  Lipeng Wu,et al.  Exploration of Osmanthus fragrans Lour.'s composition, nutraceutical functions and applications , 2021, Food Chemistry.

[3]  E. Çapanoğlu,et al.  Available technologies on improving the stability of polyphenols in food processing , 2021, Food Frontiers.

[4]  R. Aluko Food-derived Acetylcholinesterase Inhibitors as Potential Agents against Alzheimer’s Disease , 2021 .

[5]  P. Kesharwani,et al.  Evolving new-age strategies to transport therapeutics across the blood-brain-barrier. , 2021, International journal of pharmaceutics.

[6]  M. Helmy,et al.  Enhancing the in vitro and in vivo activity of itraconazole against breast cancer using miltefosine-modified lipid nanocapsules , 2021, Drug delivery.

[7]  J. Kumar,et al.  Nanotechnology: Current applications and future scope in food , 2020, Food Frontiers.

[8]  N. Acero,et al.  Neuroprotective Potential of Verbascoside Isolated from Acanthus mollis L. Leaves through Its Enzymatic Inhibition and Free Radical Scavenging Ability , 2020, Antioxidants.

[9]  Di Wang,et al.  Neuroprotective effects of verbascoside against Alzheimer’s disease via the relief of endoplasmic reticulum stress in Aβ-exposed U251 cells and APP/PS1 mice , 2020, Journal of Neuroinflammation.

[10]  Walaa H El-Maadawy,et al.  Impact of Reverse Micelle Loaded Lipid Nanocapsules on the Delivery of Gallic Acid into Activated Hepatic Stellate Cells: A Promising Therapeutic Approach for Hepatic Fibrosis , 2020, Pharmaceutical Research.

[11]  Milen I Georgiev,et al.  Therapeutic potential of phenylethanoid glycosides: A systematic review , 2020, Medicinal research reviews.

[12]  A. El-Kamel,et al.  Enhanced oral bioavailability of Tanshinone IIA using lipid nanocapsules: formulation, in-vitro appraisal and pharmacokinetics. , 2020, International journal of pharmaceutics.

[13]  O. Feron,et al.  Inhibition of colorectal cancer-associated fibroblasts by lipid nanocapsules loaded with acriflavine or paclitaxel. , 2020, International journal of pharmaceutics.

[14]  S. Reis,et al.  Quercetin lipid nanoparticles functionalized with transferrin for Alzheimer's disease. , 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[15]  W. Lu,et al.  A dual-ligand fusion peptide improves the brain-neuron targeting of nanocarriers in Alzheimer's disease mice. , 2020, Journal of controlled release : official journal of the Controlled Release Society.

[16]  V. Préat,et al.  Combinational Drug-Loaded Lipid Nanocapsules for the Treatment of Cancer. , 2019, International journal of pharmaceutics.

[17]  Yanan Liu,et al.  Quercetin-modified gold-palladium nanoparticles as a potential autophagy inducer for the treatment of Alzheimer's disease. , 2019, Journal of colloid and interface science.

[18]  Emad B. Basalious,et al.  Design of bile-based vesicles (BBVs) for hepatocytes specific delivery of Daclatasvir: Comparison of ex-vivo transenterocytic transport, in-vitro protein adsorption resistance and HepG2 cellular uptake of charged and β-sitosterol decorated vesicles , 2019, PloS one.

[19]  P. Saulnier,et al.  A comparison of different strategies for antimicrobial peptides incorporation onto/into lipid nanocapsules. , 2019, Nanomedicine.

[20]  Lukui Chen,et al.  Pep-1&borneol-Bifunctionalized Carmustine-Loaded Micelles Enhance Anti-Glioma Efficacy Through Tumor-Targeting and BBB-Penetrating. , 2019, Journal of pharmaceutical sciences.

[21]  I. Romero,et al.  Cannabidiol Enhances the Passage of Lipid Nanocapsules across the Blood-Brain Barrier Both in Vitro and in Vivo. , 2019, Molecular pharmaceutics.

[22]  B. Krishnamachary,et al.  Optimized acriflavine‐loaded lipid nanocapsules as a safe and effective delivery system to treat breast cancer , 2018, International journal of pharmaceutics.

[23]  Xiaodan Wu,et al.  Chitosan-coated liposomes as delivery systems for improving the stability and oral bioavailability of acteoside , 2018, Food Hydrocolloids.

[24]  Jing Qin,et al.  Natural Brain Penetration Enhancer-Modified Albumin Nanoparticles for Glioma Targeting Delivery. , 2018, ACS applied materials & interfaces.

[25]  F. Caruso,et al.  Overcoming the Blood–Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases , 2018, Advanced materials.

[26]  Manisha Pandey,et al.  Transferrin receptors-targeting nanocarriers for efficient targeted delivery and transcytosis of drugs into the brain tumors: a review of recent advancements and emerging trends , 2018, Drug Delivery and Translational Research.

[27]  Eugenia Trushina,et al.  Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease , 2017, Journal of Alzheimer's disease : JAD.

[28]  Shirui Mao,et al.  Enhanced blood–brain barrier transport of vinpocetine by oral delivery of mixed micelles in combination with a message guider , 2017, Journal of drug targeting.

[29]  C. Passirani,et al.  Nucleic-Acid Delivery Using Lipid Nanocapsules. , 2016, Current pharmaceutical biotechnology.

[30]  Ting Xu,et al.  Self-assembled 20-nm (64)Cu-micelles enhance accumulation in rat glioblastoma. , 2015, Journal of controlled release : official journal of the Controlled Release Society.

[31]  Bing Yang,et al.  Influence of puerarin, paeoniflorin, and menthol on structure and barrier function of tight junctions in MDCK and MDCK-MDR1 Cells , 2015 .

[32]  Milen I Georgiev,et al.  Verbascoside--a review of its occurrence, (bio)synthesis and pharmacological significance. , 2014, Biotechnology advances.

[33]  Jun Ma,et al.  Krüppel‐Like Factor 4 Regulates Blood‐Tumor Barrier Permeability via ZO‐1, Occludin and Claudin‐5 , 2014, Journal of cellular physiology.

[34]  A. Segura‐Carretero,et al.  Phenylpropanoids and their metabolites are the major compounds responsible for blood-cell protection against oxidative stress after administration of Lippia citriodora in rats. , 2013, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[35]  N. Joan Abbott,et al.  Establishment of a simplified in vitro porcine blood–brain barrier model with high transendothelial electrical resistance , 2013, Brain Research.

[36]  H. Isoda,et al.  Inhibition of Amyloid β Aggregation by Acteoside, a Phenylethanoid Glycoside , 2013, Bioscience, biotechnology, and biochemistry.

[37]  Xiongwei Zhu,et al.  Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. , 2013, Antioxidants & redox signaling.

[38]  Jianxin Wang,et al.  The Use of Borneol as an Enhancer for Targeting Aprotinin-Conjugated PEG-PLGA Nanoparticles to the Brain , 2013, Pharmaceutical Research.

[39]  N. Abbott Blood–brain barrier structure and function and the challenges for CNS drug delivery , 2013, Journal of Inherited Metabolic Disease.

[40]  Yuxia Xu,et al.  Upregulation of Heme Oxygenase-1 by Acteoside Through ERK and PI3 K/Akt Pathway Confer Neuroprotection Against Beta-Amyloid-Induced Neurotoxicity , 2012, Neurotoxicity Research.

[41]  Jianan Wang,et al.  Preparation of an anhydrous reverse micelle delivery system to enhance oral bioavailability and anti-diabetic efficacy of berberine. , 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[42]  Pascal Gayet,et al.  Reverse micelle-loaded lipid nanocarriers: a novel drug delivery system for the sustained release of doxorubicin hydrochloride. , 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[43]  Viness Pillay,et al.  A Review on Composite Liposomal Technologies for Specialized Drug Delivery , 2011, Journal of drug delivery.

[44]  J. Benoit,et al.  Reciprocal competition between lipid nanocapsules and P-gp for paclitaxel transport across Caco-2 cells. , 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[45]  J. Benoit,et al.  Lipid nanocapsules: a new platform for nanomedicine. , 2009, International journal of pharmaceutics.

[46]  Wei Lu,et al.  Lactoferrin-conjugated PEG-PLA nanoparticles with improved brain delivery: in vitro and in vivo evaluations. , 2009, Journal of controlled release : official journal of the Controlled Release Society.

[47]  S. Pastore,et al.  Molecular mechanisms underlying wound healing and anti-inflammatory properties of naturally occurring biotechnologically produced phenylpropanoid glycosides. , 2007, Cellular and molecular biology.

[48]  J. Benoit,et al.  Salting-out effect induced by temperature cycling on a water/nonionic surfactant/oil system. , 2007, The journal of physical chemistry. B.

[49]  P. Saulnier,et al.  Reorganization of lipid nanocapsules at air-water interface: Part 2. Properties of the formed surface film. , 2005, Colloids and surfaces. B, Biointerfaces.

[50]  T. Naoe,et al.  P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (MRP1) are induced by arsenic trioxide (As2O3), but are not the main mechanism of As2O3-resistance in acute promyelocytic leukemia cells , 2003, Leukemia.

[51]  J. Benoit,et al.  A Novel Phase Inversion-Based Process for the Preparation of Lipid Nanocarriers , 2002, Pharmaceutical Research.

[52]  P. Fraser,et al.  The Link between Type 2 Diabetes and Neurodegeneration: Roles for Amyloid-β, Amylin, and Tau Proteins. , 2017, Journal of Alzheimer's disease : JAD.

[53]  W. Pardridge The blood-brain barrier: Bottleneck in brain drug development , 2005, NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics.