Effects of static magnetic fields of erythrocyte rheology

Abstract The orientation of normal erythrocytes in a uniform static magnetic field (8 T maximum) has been investigated microscopically and photometrically. 1. (1) The intact erythrocytes were oriented with their disk planes parallel to the magnetic field because of the diamagnetism of the cell membrane components, particularly the transmembrane proteins (e.g., Band III, glycopholin) and the lipid bilayer. 2. (2) In contrast, the glutaraldehyde-fixed erythrocytes were oriented perpendicular to the field, perhaps because of the paramagnetism of the membrane-bound methemoglobin. 3. (3) The orientation was established within 5 s in a dilute suspension (5 × 103cells μl−1) as estimated from the change in light scattering after exposure to the magnetic field.

[1]  Muneyuki Date,et al.  Orientation of erythrocytes in a strong static magnetic field. , 1993 .

[2]  L. Tarassenko,et al.  Absorption and multiple scattering by suspensions of aligned red blood cells. , 1991, Journal of the Optical Society of America. A, Optics and image science.

[3]  Muneyuki Date,et al.  Magnetic field effect on the polymerization of fibrin fibers , 1990 .

[4]  A. Seiyama,et al.  Paramagnetic attraction of erythrocyte flow due to an inhomogeneous magnetic field , 1993 .

[5]  S. Charap,et al.  Physics of magnetism , 1964 .

[6]  J. Torbet,et al.  Oriented fibrin gels formed by polymerization in strong magnetic fields , 1981, Nature.

[7]  M. Date,et al.  High magnetic field facility at Osaka University , 1989 .

[8]  N. Maeda,et al.  Effects of an inhomogeneous magnetic field on flowing erythrocytes , 1987, European Biophysics Journal.

[9]  K. Imai,et al.  The binding of hemoglobin to red cell membrane lowers its oxygen affinity. , 1987, Journal of biochemistry.

[10]  A. Tasaki,et al.  Paramagnetic anisotropy measurements on a single crystal of deoxyhemoglobin. , 1972, Biochimica et biophysica acta.

[11]  MAKIO MURAYAMA,et al.  Orientation of Sickled Erythrocytes in a Magnetic Field , 1965, Nature.

[12]  P. Yager,et al.  Orientation of lipid tubules by a magnetic field. , 1987, Biophysical journal.

[13]  A. Blaurock,et al.  Magnetic orientation of purple membranes demonstrated by optical measurements and neutron scattering , 1977, FEBS letters.

[14]  N. Kawaguchi,et al.  Effects of a strong static magnetic field on blood platelets. , 1993, Platelets.

[15]  V. Twersky.  Absorption and multiple scattering by biological suspensions. , 1970, Journal of the Optical Society of America.

[16]  C A Gooding,et al.  AUR memorial Award. Induced alignment of flowing sickle erythrocytes in a magnetic field. A preliminary report. , 1985, Investigative radiology.

[17]  P. Low,et al.  The interaction of hemoglobin with the cytoplasmic domain of band 3 of the human erythrocyte membrane. , 1984, The Journal of biological chemistry.

[18]  Martin Blank,et al.  Electricity and Magnetism in Biology and Medicine , 1995 .

[19]  D. Melville,et al.  Direct magnetic separation of red cells from whole blood , 1975, Nature.

[20]  M. Date,et al.  High Field Diamagnetic Susceptibility and the "Curie-Weiss Law" in Organic Liquid , 1984 .