Cabergoline-related severe restrictive mitral regurgitation.

To the Editor: A 74-year-old man presented with progressive and severe dyspnea of two months' duration. The patient had Parkinson's disease that had initially been treated with levodopa, to which cabergoline had been added during the preceding four months. The physical examination was notable for increased jugular venous pressure, bilateral rales, and edema in both legs. On auscultation, a gallop rhythm and a 2/6 pansystolic murmur radiating to the axilla were noted. A chest radiograph showed mild cardiomegaly and signs of acute pulmonary edema. Electrocardiography demonstrated sinus rhythm at 80 beats per minute with left atrial enlargement. Transthoracic echocardiography revealed . . .