Characterisation of Prostate Cancer Lesions in Heterozygous Men1 Mutant Mice

[1]  T. Ishida,et al.  Menin, a product of the MENI gene, binds to estrogen receptor to enhance its activity in breast cancer cells: possibility of a novel predictive factor for tamoxifen resistance , 2010, Breast Cancer Research and Treatment.

[2]  Y. Sugimura,et al.  Role of stromal tenascin-C in mouse prostatic development and epithelial cell differentiation. , 2008, Developmental biology.

[3]  K. Sjögren,et al.  Liver-derived IGF1 enhances the androgenic response in prostate. , 2008, The Journal of endocrinology.

[4]  G. Boivin,et al.  Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer. , 2008, Cancer research.

[5]  W. Willett,et al.  Multiple loci identified in a genome-wide association study of prostate cancer , 2008, Nature Genetics.

[6]  Jieli Lu,et al.  Deregulation of anti-Mullerian hormone/BMP and transforming growth factor-beta pathways in Leydig cell lesions developed in male heterozygous multiple endocrine neoplasia type 1 mutant mice. , 2008, Endocrine-related cancer.

[7]  X. Hua,et al.  In search of tumor suppressing functions of menin , 2007, Molecular and Cellular Endocrinology.

[8]  G. Kay,et al.  Broad tumor spectrum in a mouse model of multiple endocrine neoplasia type 1 , 2007, International journal of cancer.

[9]  Kenneth N Ross,et al.  Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins. , 2006, Cancer research.

[10]  K. Mulder,et al.  Menin links estrogen receptor activation to histone H3K4 trimethylation. , 2006, Cancer research.

[11]  Chun-Peng Liao,et al.  Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis. , 2006, Cancer research.

[12]  O. Rozenblatt-Rosen,et al.  Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[13]  O. Rozenblatt-Rosen,et al.  Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[14]  Yong Lin,et al.  A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[15]  M. Rubin,et al.  Prostate Pathology of Genetically Engineered Mice: Definitions and Classification. The Consensus Report from the Bar Harbor Meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee , 2004, Cancer Research.

[16]  P. Pandolfi,et al.  Pten Dose Dictates Cancer Progression in the Prostate , 2003, PLoS biology.

[17]  Zhao-Qi Wang,et al.  Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1. , 2003, Molecular endocrinology.

[18]  A. D. De Marzo,et al.  Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling? , 2003, The Journal of clinical endocrinology and metabolism.

[19]  A. Aguzzi,et al.  Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs , 2003, Mechanisms of Development.

[20]  S. Inoue,et al.  Zone-dependent expression of estrogen receptors alpha and beta in human benign prostatic hyperplasia. , 2003, The Journal of clinical endocrinology and metabolism.

[21]  M. Loda,et al.  Diagnostic Utility of Immunohistochemical Staining for p63, a Sensitive Marker of Prostatic Basal Cells , 2002, Modern Pathology.

[22]  Chawnshang Chang,et al.  Differential Modulation of Androgen Receptor-mediated Transactivation by Smad3 and Tumor Suppressor Smad4* , 2002, The Journal of Biological Chemistry.

[23]  R. Cardiff,et al.  Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[24]  P. Pandolfi,et al.  Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse , 2001, Nature Genetics.

[25]  F. Collins,et al.  A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[26]  O. Kallioniemi,et al.  Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression. , 2000, Cancer research.

[27]  V. Godfrey,et al.  Functional Collaboration between Different Cyclin-Dependent Kinase Inhibitors Suppresses Tumor Growth with Distinct Tissue Specificity , 2000, Molecular and Cellular Biology.

[28]  R. Cardiff,et al.  Roles for Nkx3.1 in prostate development and cancer. , 1999, Genes & development.

[29]  L. Liotta,et al.  Somatic mutations of the MEN1 tumor suppressor gene detected in sporadic angiofibromas. , 1998, The Journal of investigative dermatology.

[30]  R. Thakker Multiple endocrine neoplasia--syndromes of the twentieth century. , 1998, The Journal of clinical endocrinology and metabolism.

[31]  M. Matzuk,et al.  Genetic analysis of the Müllerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation. , 1996, Genes & development.

[32]  A. Bradley,et al.  Synergistic effects of inhibins and müllerian-inhibiting substance on testicular tumorigenesis. , 1995, Molecular endocrinology.

[33]  R. Behringer,et al.  Müllerian-inhibiting substance function during mammalian sexual development , 1994, Cell.

[34]  P. Carroll,et al.  An oncogenic role for the multiple endocrine neoplasia type 1 gene in prostate cancer , 2009, Prostate Cancer and Prostatic Diseases.

[35]  N. Hussein,et al.  Reconstituted expression of menin in Men1-deficient mouse Leydig tumour cells induces cell cycle arrest and apoptosis. , 2007, European journal of cancer.

[36]  P. Bertolino,et al.  Analysis of p27Kip1 Expression in Insulinomas Developed in Pancreatic β-cell Specific Men1 Mutant Mice , 2005, Familial Cancer.

[37]  Massimo Loda,et al.  Role of p27 in Prostate Carcinogenesis , 2004, Cancer and Metastasis Reviews.

[38]  M. Brandi,et al.  [Multiple endocrine neoplasia associated with multiple lipomas]. , 1998, Medizinische Klinik.

[39]  A. Bradley,et al.  Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice. , 1992, Nature.

[40]  B. Rasmussen,et al.  Bmc Cancer , 2022 .