Vinorelbine-Induced Oxidative Injury in Human Endothelial Cells Mediated by AMPK/PKC/NADPH/NF-κB Pathways

[1]  G. Renier,et al.  Palmitate induces C-reactive protein expression in human aortic endothelial cells. Relevance to fatty acid-induced endothelial dysfunction. , 2011, Metabolism: clinical and experimental.

[2]  Li Zhang,et al.  Metformin improves cardiac function in rats via activation of AMP‐activated protein kinase , 2011, Clinical and experimental pharmacology & physiology.

[3]  H. Abboud,et al.  AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes* , 2010, The Journal of Biological Chemistry.

[4]  S. Del Turco,et al.  The lectin-like oxidized low-density lipoprotein receptor-1 and its soluble form: cardiovascular implications. , 2010, Journal of atherosclerosis and thrombosis.

[5]  Mingyuan Wu,et al.  Activation of AMP-Activated Protein Kinase Inhibits Oxidized LDL-Triggered Endoplasmic Reticulum Stress In Vivo , 2010, Diabetes.

[6]  Y. Takeishi,et al.  LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells. , 2009, Cardiovascular research.

[7]  B. Fisslthaler,et al.  Activation and signaling by the AMP-activated protein kinase in endothelial cells. , 2009, Circulation research.

[8]  J. Mehta,et al.  Intracellular signaling of LOX-1 in endothelial cell apoptosis. , 2009, Circulation research.

[9]  J. Suttles,et al.  Adenosine 5′-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype1 , 2008, The Journal of Immunology.

[10]  L. Franco,et al.  Rosiglitazone Reduces Glucose-Induced Oxidative Stress Mediated by NAD(P)H Oxidase via AMPK-Dependent Mechanism , 2007, Arteriosclerosis, thrombosis, and vascular biology.

[11]  D. Hardie,et al.  AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy , 2007, Nature Reviews Molecular Cell Biology.

[12]  G. Du,et al.  Lectin-like oxidized low-density lipoprotein receptor-1, a new promising target for the therapy of atherosclerosis? , 2007, Cardiovascular drug reviews.

[13]  B. Tesfamariam,et al.  Endothelial injury in the initiation and progression of vascular disorders. , 2007, Vascular pharmacology.

[14]  L. Franco,et al.  Insulin generates free radicals in human fibroblasts ex vivo by a protein kinase C-dependent mechanism, which is inhibited by pravastatin. , 2006, Free radical biology & medicine.

[15]  Kunihiro Suzuki,et al.  Metformin Inhibits Cytokine-Induced Nuclear Factor &kgr;B Activation Via AMP-Activated Protein Kinase Activation in Vascular Endothelial Cells , 2006, Hypertension.

[16]  C. Thompson,et al.  The survival kinases Akt and Pim as potential pharmacological targets. , 2005, The Journal of clinical investigation.

[17]  G. Feldman,et al.  Protein Kinase Cδ Is Required for p47phox Phosphorylation and Translocation in Activated Human Monocytes1 , 2004, The Journal of Immunology.

[18]  A. Shah,et al.  Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology. , 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

[19]  R. El Bekay,et al.  Stimulators of AMP‐activated protein kinase inhibit the respiratory burst in human neutrophils , 2004, FEBS letters.

[20]  A. Nègre-Salvayre,et al.  Dual Role of Oxidized LDL on the NF-KappaB Signaling Pathway , 2004, Free radical research.

[21]  M. Jordan,et al.  Microtubules as a target for anticancer drugs , 2004, Nature Reviews Cancer.

[22]  K. Walsh,et al.  Modulation by Peroxynitrite of Akt- and AMP-activated Kinase-dependent Ser1179 Phosphorylation of Endothelial Nitric Oxide Synthase* , 2002, The Journal of Biological Chemistry.

[23]  K. Ando,et al.  PPARgamma ligands inhibit TNF-alpha-induced LOX-1 expression in cultured endothelial cells. , 2001, Biochemical and biophysical research communications.

[24]  B. Hill,et al.  Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine. , 2001, Molecular pharmacology.

[25]  D. Power,et al.  Coordinated Control of Endothelial Nitric-oxide Synthase Phosphorylation by Protein Kinase C and the cAMP-dependent Protein Kinase* , 2001, The Journal of Biological Chemistry.

[26]  E. Chavakis,et al.  Oxidized LDL Inhibits Vascular Endothelial Growth Factor-Induced Endothelial Cell Migration by an Inhibitory Effect on the Akt/Endothelial Nitric Oxide Synthase Pathway , 2001, Circulation.

[27]  F. Pinguet,et al.  High-performance liquid chromatographic determination of vinorelbine in human plasma and blood: application to a pharmacokinetic study. , 2000, Journal of chromatography. B, Biomedical sciences and applications.

[28]  K. Umesono,et al.  Feedback control of cyclooxygenase-2 expression through PPARgamma. , 2000, The Journal of biological chemistry.

[29]  D. Sorescu,et al.  NAD(P)H oxidase: role in cardiovascular biology and disease. , 2000, Circulation research.

[30]  Christopher K. Glass,et al.  The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation , 1998, Nature.

[31]  Bruce M. Spiegelman,et al.  Inhibition of Adipogenesis Through MAP Kinase-Mediated Phosphorylation of PPARγ , 1996, Science.

[32]  R. Cn,et al.  Assessing and managing venous irritation associated with vinorelbine tartrate (Navelbine) , 1995 .

[33]  T. Springer Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm , 1994, Cell.

[34]  D. Budman New vinca alkaloids and related compounds. , 1992, Seminars in oncology.

[35]  K. Umesono,et al.  Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors , 1992, Nature.

[36]  E. Jaffe,et al.  Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. , 1973, The Journal of clinical investigation.

[37]  M. Espié,et al.  A Review of the Antitumour Activity of Vinorelbine in Breast Cancer , 2012, Drugs.

[38]  Jae Heun Lee,et al.  7,8-didehydrocimigenol from Cimicifugae rhizoma inhibits TNF-α-induced VCAM-1 but not ICAM-1expression through upregulation of PPAR-γ in human endothelial cells. , 2011, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[39]  T. Yano,et al.  Role of oxidative stress in vinorelbine-induced vascular endothelial cell injury. , 2010, Free radical biology & medicine.

[40]  D. Hardie,et al.  The AMP-activated protein kinase--fuel gauge of the mammalian cell? , 1997, European journal of biochemistry.

[41]  A. Baldwin,et al.  The NF-kappa B and I kappa B proteins: new discoveries and insights. , 1996, Annual review of immunology.

[42]  A. Baldwin,et al.  THE NF-κB AND IκB PROTEINS: New Discoveries and Insights , 1996 .

[43]  R. Gralla,et al.  Assessing and managing venous irritation associated with vinorelbine tartrate (Navelbine) , 1995, Oncology Nursing Forum.

[44]  J. Sørensen Vinorelbine. A review of its antitumour activity in lung cancer. , 1992, Drugs.