Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF).

[1]  J. Qin,et al.  ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling. , 2012, Current opinion in cell biology.

[2]  BeatrizHerranz,et al.  Integrin-Linked Kinase Regulates Vasomotor Function by Preventing Endothelial Nitric Oxide Synthase Uncoupling , 2012 .

[3]  I. Rodrı́guez-Crespo,et al.  Integrin-Linked Kinase Regulates Vasomotor Function by Preventing Endothelial Nitric Oxide Synthase Uncoupling: Role in Atherosclerosis , 2012, Circulation research.

[4]  Gaudenz Danuser,et al.  Scale integration: the structure and dynamics of macromolecular assemblies, cells and tissues. , 2012, Current opinion in cell biology.

[5]  Kerry-Ann Nakrieko,et al.  Targeted inactivation of integrin-linked kinase in hair follicle stem cells reveals an important modulatory role in skin repair after injury , 2011, Molecular biology of the cell.

[6]  J. Qin,et al.  Biochemical, Proteomic, Structural, and Thermodynamic Characterizations of Integrin-linked Kinase (ILK) , 2011, The Journal of Biological Chemistry.

[7]  R. Fässler,et al.  Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts – role of TGFβ1 levels and RhoA activity , 2010, Journal of Cell Science.

[8]  L. Foster,et al.  Integrin-Linked Kinase Is a Functional Mn2+-Dependent Protein Kinase that Regulates Glycogen Synthase Kinase-3β (GSK-3β) Phosphorylation , 2010, PloS one.

[9]  L. Foster,et al.  Integrin-Linked Kinase Is a Functional Mn 2 +-Dependent Protein Kinase that Regulates Glycogen Synthase Kinase-3 b ( GSK-3 b ) Phosphorylation , 2010 .

[10]  G. Michalopoulos,et al.  Enhanced liver regeneration following changes induced by hepatocyte‐specific genetic ablation of integrin‐linked kinase , 2009, Hepatology.

[11]  D. Stolz,et al.  Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis. , 2009, Journal of the American Society of Nephrology : JASN.

[12]  J. Beaulieu,et al.  Specific signaling cascades involved in cell spreading during healing of micro‐wounded gastric epithelial monolayers , 2008, Journal of cellular biochemistry.

[13]  J. Woodgett,et al.  GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism. , 2008, The Journal of clinical investigation.

[14]  S. Dedhar,et al.  Integrin-linked kinase – essential roles in physiology and cancer biology , 2008, Journal of Cell Science.

[15]  Marie-Pier Tétreault,et al.  Krüppel-like Factor 5 Controls Keratinocyte Migration via the Integrin-linked Kinase* , 2008, Journal of Biological Chemistry.

[16]  S. Dedhar,et al.  Impaired hair follicle morphogenesis and polarized keratinocyte movement upon conditional inactivation of integrin-linked kinase in the epidermis. , 2008, Molecular biology of the cell.

[17]  T. Willson,et al.  Ligand activation of peroxisome proliferator-activated receptor-β/δ(PPARβ/δ) inhibits cell growth of human N/TERT-1 keratinocytes , 2007 .

[18]  S. Dedhar,et al.  Integrin-Linked Kinase at the Heart of Cardiac Contractility, Repair, and Disease , 2007, Circulation research.

[19]  D. W. Vinter,et al.  Smooth muscle releases an epithelial cell scatter factor which binds to heparin , 1989, In Vitro Cellular & Developmental Biology.

[20]  T. Willson,et al.  Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes. , 2007, Cellular signalling.

[21]  S. Werner,et al.  Regulation of epidermal homeostasis and repair by phosphoinositide 3-kinase , 2006, Journal of Cell Science.

[22]  J. López-Novoa,et al.  Involvement of H- and N-Ras isoforms in transforming growth factor-beta1-induced proliferation and in collagen and fibronectin synthesis. , 2006, Experimental cell research.

[23]  W. Jiang,et al.  The molecular and clinical impact of hepatocyte growth factor, its receptor, activators, and inhibitors in wound healing. , 2006, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[24]  Xianglin Shi,et al.  ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling , 2005, Oncogene.

[25]  M. Barbacid,et al.  Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development. , 2005, Cancer cell.

[26]  L. Dworkin,et al.  Hepatocyte growth factor induces an endothelin-mediated decline in glomerular filtration rate. , 2005, American journal of physiology. Renal physiology.

[27]  N. Lloberas,et al.  Regression of advanced diabetic nephropathy by hepatocyte growth factor gene therapy in rats. , 2004, Diabetes.

[28]  吉田 佐保.  Neutralization of Hepatocyte Growth Factor Leads to Retarded Cutaneous Wound Healing Associated with Decreased Neovascularization and Granulation Tissue Formation , 2004 .

[29]  W. Wahli,et al.  Critical roles of the nuclear receptor PPARβ (peroxisome-proliferator-activated receptor β) in skin wound healing , 2004 .

[30]  J. Torras,et al.  Intramuscular SP1017‐formulated DNA electrotransfer enhances transgene expression and distributes hHGF to different rat tissues , 2004, The journal of gene medicine.

[31]  W. Wahli,et al.  Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator-activated receptor beta) in skin wound healing. , 2004, Biochemical Society transactions.

[32]  S. Dedhar,et al.  Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes , 2003, The Journal of cell biology.

[33]  K. Yoshikawa,et al.  Neutralization of hepatocyte growth factor leads to retarded cutaneous wound healing associated with decreased neovascularization and granulation tissue formation. , 2003, The Journal of investigative dermatology.

[34]  K. Dono,et al.  Attenuated acute liver injury in mice by naked hepatocyte growth factor gene transfer into skeletal muscle with electroporation , 2002, Gut.

[35]  J. Couper,et al.  Hepatocyte growth factor and macrophage-stimulating protein are upregulated during excisional wound repair in rats , 2001, Cell and Tissue Research.

[36]  B. Janji,et al.  Autocrine TGF‐β‐regulated expression of adhesion receptors and integrin‐linked kinase in HT‐144 melanoma cells correlates with their metastatic phenotype , 1999, International journal of cancer.

[37]  C. Wu,et al.  Expression of the integrin-linked kinase (ILK) in mouse skin: loss of expression in suprabasal layers of the epidermis and up-regulation by erbB-2. , 1998, The American journal of pathology.

[38]  Paul Martin,et al.  Wound Healing--Aiming for Perfect Skin Regeneration , 1997, Science.

[39]  S. Dedhar,et al.  Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase , 1996, Nature.

[40]  L. Naldini,et al.  Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth , 1992, The Journal of cell biology.

[41]  K. Matsumoto,et al.  Marked stimulation of growth and motility of human keratinocytes by hepatocyte growth factor. , 1991, Experimental cell research.

[42]  K. Matsumoto,et al.  Hepatocyte growth factor is a potent stimulator of human melanocyte DNA synthesis and growth. , 1991, Biochemical and biophysical research communications.

[43]  G. Michalopoulos,et al.  Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 transformed RPTE. , 1991, Biochemical and biophysical research communications.

[44]  Michael Stoker,et al.  Scatter factor is a fibroblast-derived modulator of epithelial cell mobility , 1987, Nature.