DOCUMENT: a system for classifying drug-related problems in community pharmacy

Background Drug-related problems (DRPs) are a major burden on the Australian healthcare system. Community pharmacists are in an ideal position to detect, prevent, and resolve these DRPs. Objective To develop and validate an easy-to-use documentation system for pharmacists to classify and record DRPs, and to investigate the nature and frequency of clinical interventions undertaken by Australian community pharmacists to prevent or resolve them. Setting Australian community pharmacies. Method The DOCUMENT classification system was developed, validated and refined during two pilot studies. The system was then incorporated into software installed in 185 Australian pharmacies to record DRPs and clinical interventions undertaken by pharmacists during a 12-week trial. Main outcome measure The number and nature of DRPs detected within Australian community pharmacies. Results A total of 5,948 DRPs and clinical interventions were documented from 2,013,923 prescriptions dispensed during the trial (intervention frequency 0.3%). Interventions were commonly related to Drug selection problems (30.7%) or Educational issues (23.7%). Pharmacists made an average of 1.6 recommendations per intervention, commonly relating to A change in therapy (40.1%) and Provision of information (34.7%). Almost half of interventions (42.6%) were classified by recording pharmacists as being at a higher level of clinical significance. Conclusion The DOCUMENT system provided pharmacists with a useful and easy-to-use tool for recording DRPs and clinical interventions. Results from the trial have provided a better understanding of the frequency and nature of clinical interventions performed in Australian community pharmacies, and lead to a national implementation of the system.

[1]  Florence T. Bourgeois,et al.  Adverse drug events in the outpatient setting: an 11‐year national analysis , 2010, Pharmacoepidemiology and drug safety.

[2]  M. J. Martín-Calero,et al.  Pharmaceutical care: past, present and future. , 2004, Current pharmaceutical design.

[3]  J. Hernández,et al.  Adverse drug events in ambulatory care. , 2003, The New England journal of medicine.

[4]  E. Roughead,et al.  Australia and New Zealand Health Policy Open Access Medication Safety in Acute Care in Australia: Where Are We Now? Part 1: a Review of the Extent and Causes of Medication Problems 2002– 2008 , 2022 .

[5]  V. Hjellvik,et al.  Evaluating categorisation and clinical relevance of drug-related problems in medication reviews , 2010, Pharmacy World & Science.

[6]  C. Hepler,et al.  Opportunities and responsibilities in pharmaceutical care. , 1990, American journal of hospital pharmacy.

[7]  G. Laekeman,et al.  Frequency and trends of interventions of prescriptions in Flemish community pharmacies , 2003, Pharmacy World and Science.

[8]  A. Melander,et al.  Drug‐related problems and pharmacy interventions in community practice , 1999 .

[9]  K. Hersberger,et al.  Classification of drug-related problems with new prescriptions using a modified PCNE classification system , 2010, Pharmacy World & Science.

[10]  G. Peterson Documenting clinical interventions in community pharmacy: PROMISe III , 2010 .

[11]  B. Hug,et al.  Drug-related problems: evaluation of a classification system in the daily practice of a Swiss University Hospital , 2008, Pharmacy World & Science.

[12]  D. Ashcroft,et al.  Prevalence of Adverse Drug Events in Ambulatory Care: A Systematic Review , 2011, The Annals of pharmacotherapy.

[13]  M. Bouvy,et al.  Effects of Medication Review on Drug-Related Problems in Patients Using Automated Drug-Dispensing Systems , 2011, Drugs & aging.

[14]  Azeem Majeed,et al.  Ten-year trends in hospital admissions for adverse drug reactions in England 1999–2009 , 2010, Journal of the Royal Society of Medicine.

[15]  M. Schaefer Discussing basic principles for a coding system of drug-related problems: the case of PI-Doc® , 2002, Pharmacy World and Science.

[16]  L. Westerlund,et al.  Pharmaceutical Care in Community Pharmacies: Practice and Research in Sweden , 2006, The Annals of pharmacotherapy.

[17]  C. Poole,et al.  Preventable Drug-Related Hospital Admissions , 2002, The Annals of pharmacotherapy.

[18]  M. Pirmohamed,et al.  Which drugs cause preventable admissions to hospital? A systematic review. , 2007, British journal of clinical pharmacology.