A Survey of Missing Value Imputation for Gene Expression Data Using Deep Learning Models

ion Gene expression analysis is essential for transcriptomics studies. However, due to unintended noise generation by the device or an insufficient number of mRNA molecules, the rate of missing values, which are false zero, is high. Therefore, a number of deep learning-based studies have been conducted to impute missing values. In this paper, we will overview the state-of-the-art deep learning-based models: DeepImpute, AutoImpute, Deep Count Autoencoder Network (DCA), scGAIN, scIGANs.