论文信息 - Alcohol Dependence Produced in Mice by Inhalation of Ethanol: Grading the Withdrawal Reaction

Alcohol Dependence Produced in Mice by Inhalation of Ethanol: Grading the Withdrawal Reaction

Intoxicating blood levels of ethanol are maintained for several days in mice housed in an atmosphere of ethanol vapor. On removal from the alcohol, all the mice develop withdrawal signs. The signs can be graded to indicate the time course and intensity of the withdrawal reaction.

D. B. Goldstein | Nandita Pal

[1] A. Goldstein,et al. Alcohol Dependence and Opiate Dependence: Lack of Relationship in Mice , 1971, Science.

[2] C. Lieber,et al. Effects of pyrazole on hepatic function and structure. , 1970, Laboratory investigation; a journal of technical methods and pathology.

[3] U. Rydberg,et al. Inhibition of ethanol metabolism in vivo by administration of pyrazole. , 1969, Biochemical pharmacology.

[4] G. Freund. Alcohol withdrawal syndrome in mice. , 1969, Archives of neurology.

[5] C. F. Essig,et al. Convulsions and Hallucinatory Behavior , 1968 .

[6] T. Yonetani,et al. On the effects of some heterocyclic compounds on the enzymic activity of liver alcohol dehydrogenase. , 1969, Acta chemica Scandinavica.