Mutational alteration of the breakage/resealing subunit of bacteriophage T4 DNA topoisomerase confers resistance to antitumor agent m-AMSA

[1]  T. Andoh,et al.  [Inhibitors of DNA topoisomerases]. , 1990, Gan to kagaku ryoho. Cancer & chemotherapy.

[2]  D. Sullivan,et al.  Purification and characterization of an altered topoisomerase II from a drug-resistant Chinese hamster ovary cell line. , 1989, Biochemistry.

[3]  T J O'Donnell,et al.  Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug--DNA binding model. , 1989, Biochemistry.

[4]  H. Bernstein,et al.  Bacteriophage T4 genetic homologies with bacteria and eucaryotes , 1989, Journal of bacteriology.

[5]  W. Kohlbrenner,et al.  Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes. , 1989, The Journal of biological chemistry.

[6]  J. Leatherwood,et al.  Bacteriophage T4 DNA topoisomerase is the target of antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) in T4-infected Escherichia coli. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[7]  W. Ross,et al.  DNA binding by epipodophyllotoxins and N-acyl anthracyclines: implications for mechanism of topoisomerase II inhibition. , 1988, Molecular pharmacology.

[8]  C. Lutz,et al.  Syrinx 2A: an improved lambda phage vector designed for screening DNA libraries by recombination in vivo. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[9]  W. M. Huang,et al.  Nucleotide sequence of a type II DNA topoisomerase gene. Bacteriophage T4 gene 39. , 1986, Nucleic acids research.

[10]  W. Huang The 52-protein subunit of T4 DNA topoisomerase is homologous to the gyrA-protein of gyrase. , 1986, Nucleic acids research.

[11]  J. Yamagishi,et al.  Nalidixic acid-resistant mutations of the gyrB gene of Escherichia coli , 1986, Molecular and General Genetics MGG.

[12]  M. Waring,et al.  DNA sequence preferences for the anti‐cancer drug mitoxanthrone and related anthraquinones revealed by DNase I footprinting , 1986, FEBS letters.

[13]  L. Liu,et al.  Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. , 1984, The Journal of biological chemistry.

[14]  L. Liu,et al.  Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II. , 1984, Science.

[15]  L. Liu,et al.  Identification of the breakage-reunion subunit of T4 DNA topoisomerase. , 1984, The Journal of biological chemistry.

[16]  B. Alberts,et al.  Site-specific recognition of bacteriophage T4 DNA by T4 type II DNA topoisomerase and Escherichia coli DNA gyrase. , 1984, The Journal of biological chemistry.

[17]  R. Wilkins,et al.  Identification of the specific sites of interaction between intercalating drugs and DNA. , 1984, Chemico-biological interactions.

[18]  L. Liu,et al.  Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[19]  J. Dabrowiak Sequence specificity of drug-DNA interactions. , 1983, Life sciences.

[20]  A. Seasholtz,et al.  Identification of bacteriophage T4 gene 60 product and a role for this protein in DNA topoisomerase. , 1983, The Journal of biological chemistry.

[21]  J. Wang,et al.  Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA. , 1980, The Journal of biological chemistry.

[22]  N. Cozzarelli DNA gyrase and the supercoiling of DNA. , 1980, Science.

[23]  N. Cozzarelli,et al.  Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[24]  M. Gellert,et al.  Nalidixic acid resistance: a second genetic character involved in DNA gyrase activity. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[25]  J. Vinograd,et al.  The problems of eukaryotic and prokaryotic DNA packaging and in vivo conformation posed by superhelix density heterogeneity. , 1977, Nucleic acids research.

[26]  M. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[27]  M. Waring,et al.  Variation of the supercoils in closed circular DNA by binding of antibiotics and drugs: evidence for molecular models involving intercalation. , 1970, Journal of molecular biology.

[28]  J. Yamagishi,et al.  Quinolone-resistant mutations of the gyrA gene of Escherichia coli , 2004, Molecular and General Genetics MGG.

[29]  W. Ross,et al.  DNA topoisomerase II: a primer on the enzyme and its unique role as a multidrug target in cancer chemotherapy. , 1987, Pharmacology & therapeutics.

[30]  M. Gellert,et al.  Mechanistic aspects of DNA topoisomerases. , 1986, Advances in protein chemistry.

[31]  Sutton Sm,et al.  DNA sequence preferences for the anti-cancer drug mitoxanthrone and related anthraquinones revealed by DNase I footprinting , 1986 .

[32]  C. Yanisch-Perron,et al.  Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. , 1985, Gene.

[33]  L. Liu,et al.  Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. , 1984, The Journal of biological chemistry.

[34]  C. Jongeneel,et al.  Escherichia coli phage T4 topoisomerase. , 1983, Methods in enzymology.

[35]  L. Liu,et al.  DNA topoisomerases--enzymes that catalyse the breaking and rejoining of DNA. , 1983, CRC critical reviews in biochemistry.

[36]  M. Gellert,et al.  DNA gyrase: site-specific interactions and transient double-strand breakage of DNA. , 1981, Cold Spring Harbor symposia on quantitative biology.

[37]  M. Waring,et al.  DNA modification and cancer. , 1981, Annual review of biochemistry.