Role of the IL-33-ST2 axis in sepsis

[1]  F. Liew,et al.  Interleukin-33 in health and disease , 2016, Nature Reviews Immunology.

[2]  A. Lehuen,et al.  Ablation of interaction between IL-33 and ST2+ regulatory T cells increases immune cell-mediated hepatitis and activated NK cell liver infiltration. , 2016, American journal of physiology. Gastrointestinal and liver physiology.

[3]  H. Turnquist,et al.  Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD. , 2016, Blood.

[4]  E. Seeley,et al.  Therapeutic Targets in Sepsis: Past, Present, and Future. , 2016, Clinics in chest medicine.

[5]  G. Martin,et al.  The Changing Epidemiology and Definitions of Sepsis. , 2016, Clinics in chest medicine.

[6]  Yunjun Liu,et al.  Interleukin-33 facilitates neutrophil recruitment and bacterial clearance in S. aureus-caused peritonitis. , 2016, Molecular immunology.

[7]  H. Castro-Faria-Neto,et al.  Sepsis: in search of cure , 2016, Inflammation Research.

[8]  P. Foster,et al.  MicroRNA-487b Is a Negative Regulator of Macrophage Activation by Targeting IL-33 Production , 2016, The Journal of Immunology.

[9]  D. Landsittel,et al.  Elevated ST2 Distinguishes Incidences of Pediatric Heart and Small Bowel Transplant Rejection , 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[10]  Christopher W Seymour,et al.  Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). , 2016, JAMA.

[11]  C. Benoist,et al.  Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells. , 2016, Immunity.

[12]  A. Bayat,et al.  IL-33-dependent group 2 innate lymphoid cells promote cutaneous wound healing , 2015, The Journal of investigative dermatology.

[13]  M. Hur,et al.  Soluble ST2 Has a Prognostic Role in Patients With Suspected Sepsis , 2015, Annals of laboratory medicine.

[14]  C. Akdis,et al.  An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers. , 2015, Immunity.

[15]  H. Fukui,et al.  Production of interleukin (IL)-33 in the lungs during multiple antigen challenge-induced airway inflammation in mice, and its modulation by a glucocorticoid. , 2015, European journal of pharmacology.

[16]  Bettina L. Lee,et al.  Caspase‐11: arming the guards against bacterial infection , 2015, Immunological reviews.

[17]  S. Opal,et al.  Sepsis: a roadmap for future research. , 2015, The Lancet. Infectious diseases.

[18]  F. Takei,et al.  Lung ILC2s link innate and adaptive responses in allergic inflammation. , 2015, Trends in immunology.

[19]  B. Ryffel,et al.  IL-33-Mediated Protection against Experimental Cerebral Malaria Is Linked to Induction of Type 2 Innate Lymphoid Cells, M2 Macrophages and Regulatory T Cells , 2015, PLoS pathogens.

[20]  J. Girard,et al.  IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy. , 2014, Current opinion in immunology.

[21]  H. Turnquist,et al.  IL-33 Is an Unconventional Alarmin That Stimulates IL-2 Secretion by Dendritic Cells To Selectively Expand IL-33R/ST2+ Regulatory T Cells , 2014, The Journal of Immunology.

[22]  Yasmine Belkaid,et al.  The Alarmin IL-33 Promotes Regulatory T Cell Function in the Intestine , 2014, Nature.

[23]  D. Weiner,et al.  Interleukin 33: a switch-hitting cytokine. , 2014, Current opinion in immunology.

[24]  Hassane Njimi,et al.  Assessment of the worldwide burden of critical illness: the intensive care over nations (ICON) audit. , 2014, The Lancet. Respiratory medicine.

[25]  S. Li,et al.  Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis , 2014, Cell Death and Differentiation.

[26]  R. Bellomo,et al.  Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000-2012. , 2014, JAMA.

[27]  M. Gold,et al.  Group 2 Innate Lymphoid Cells Are Critical for the Initiation of Adaptive T Helper 2 Cell-Mediated Allergic Lung Inflammation , 2014, Immunity.

[28]  D. Weiner,et al.  Alarmin IL-33 acts as an immunoadjuvant to enhance antigen-specific tumor immunity. , 2014, Cancer research.

[29]  R. Peebles,et al.  Respiratory Syncytial Virus Induces IL-25 and IL-33 Production In The Lungs , 2014 .

[30]  Hui-Rong Jiang,et al.  Emerging role of interleukin‐33 in autoimmune diseases , 2014, Immunology.

[31]  J. Rello,et al.  Human mesenchymal stem cells overexpressing the IL-33 antagonist soluble IL-1 receptor-like-1 attenuate endotoxin-induced acute lung injury. , 2013, American journal of respiratory cell and molecular biology.

[32]  T. van der Poll,et al.  Role of Interleukin 1 Receptor Like 1 (ST2) in Gram-Negative and Gram-Positive Sepsis in Mice , 2013, Shock.

[33]  J. Bernhagen,et al.  Cytokines in Sepsis: Potent Immunoregulators and Potential Therapeutic Targets—An Updated View , 2013, Mediators of inflammation.

[34]  T. van der Poll,et al.  Host innate immune responses to sepsis , 2013, Virulence.

[35]  B. Carr,et al.  Benchmarking the Incidence and Mortality of Severe Sepsis in the United States* , 2013, Critical care medicine.

[36]  C. Hrusch,et al.  IL-33-dependent induction of allergic lung inflammation by FcγRIII signaling. , 2013, The Journal of clinical investigation.

[37]  Dirk E. Smith,et al.  IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms , 2012, Proceedings of the National Academy of Sciences.

[38]  A. McKenzie,et al.  IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation , 2012, European journal of immunology.

[39]  S. Nakae,et al.  Interleukin‐33 in allergy , 2012, Allergy.

[40]  S. Tominaga,et al.  Soluble ST2 protein inhibits LPS stimulation on monocyte-derived dendritic cells , 2012, Cellular and Molecular Immunology.

[41]  F. Liew,et al.  Interleukin-33 and the function of innate lymphoid cells. , 2012, Trends in immunology.

[42]  S. Baldus,et al.  Depletion of neutrophil extracellular traps in vivo results in hypersusceptibility to polymicrobial sepsis in mice , 2012, Critical Care.

[43]  P. Zhu,et al.  Interleukin-33 Ameliorates Experimental Colitis through Promoting Th2/Foxp3+ Regulatory T-Cell Responses in Mice , 2012, Molecular medicine.

[44]  S. Leppla,et al.  Rapid induction of inflammatory lipid mediators by the inflammasome in vivo , 2012, Nature.

[45]  N. Arsenijević,et al.  IL-33/ST2 axis in inflammation and immunopathology , 2012, Immunologic research.

[46]  T. Lagu,et al.  Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007 , 2012, Critical care medicine.

[47]  H. Kita,et al.  IL-33–Responsive Lineage−CD25+CD44hi Lymphoid Cells Mediate Innate Type 2 Immunity and Allergic Inflammation in the Lungs , 2012, The Journal of Immunology.

[48]  A. McKenzie,et al.  Nuocytes: expanding the innate cell repertoire in type‐2 immunity , 2011, Journal of leukocyte biology.

[49]  Xinchun Chen,et al.  IL‐33 synergizes with TCR and IL‐12 signaling to promote the effector function of CD8+ T cells , 2011, European journal of immunology.

[50]  K. Isse,et al.  IL-33 Expands Suppressive CD11b+ Gr-1int and Regulatory T Cells, including ST2L+ Foxp3+ Cells, and Mediates Regulatory T Cell-Dependent Promotion of Cardiac Allograft Survival , 2011, The Journal of Immunology.

[51]  H. Redmond,et al.  Increased Susceptibility of ST2-Deficient Mice to Polymicrobial Sepsis Is Associated with an Impaired Bactericidal Function , 2011, The Journal of Immunology.

[52]  L. O’Neill.  A critical role for citrate metabolism in LPS signalling. , 2011, The Biochemical journal.

[53]  Ya-Jen Chang,et al.  Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity , 2011, Nature Immunology.

[54]  B. Ryffel,et al.  IL‐33‐activated dendritic cells are critical for allergic airway inflammation , 2011, European journal of immunology.

[55]  G. Rogler,et al.  A role for interleukin-33 in TH2-polarized intestinal inflammation? , 2011, Mucosal Immunology.

[56]  Jiayong Zhu,et al.  Adenovirus‐mediated overexpression of soluble ST2 provides a protective effect on lipopolysaccharide‐induced acute lung injury in mice , 2011, Clinical and experimental immunology.

[57]  C. Gabay,et al.  Interleukin-33 biology with potential insights into human diseases , 2011, Nature Reviews Rheumatology.

[58]  T. van der Poll,et al.  Loss of suppression of tumorigenicity 2 (ST2) gene reverses sepsis-induced inhibition of lung host defense in mice. , 2011, American journal of respiratory and critical care medicine.

[59]  J. Inoue,et al.  Paracrine IL-33 Stimulation Enhances Lipopolysaccharide-Mediated Macrophage Activation , 2011, PloS one.

[60]  Lyle L. Moldawer,et al.  A Paradoxical Role for Myeloid-Derived Suppressor Cells in Sepsis and Trauma , 2011, Molecular medicine.

[61]  Shoko Iwaki,et al.  Amplification of cytokine production through synergistic activation of NFAT and AP‐1 following stimulation of mast cells with antigen and IL‐33 , 2011, European journal of immunology.

[62]  S. Nakae,et al.  IL-33 and Airway Inflammation , 2011, Allergy, asthma & immunology research.

[63]  I. McInnes,et al.  Interleukin‐33: a novel mediator with a role in distinct disease pathologies , 2011, Journal of internal medicine.

[64]  S. Opal.  New perspectives on immunomodulatory therapy for bacteraemia and sepsis. , 2010, International journal of antimicrobial agents.

[65]  A. Matsuda,et al.  IL-33 Mediates Inflammatory Responses in Human Lung Tissue Cells , 2010, The Journal of Immunology.

[66]  F. Liew,et al.  Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection , 2010, Nature Medicine.

[67]  H. Redmond,et al.  ST2 Negatively Regulates TLR2 Signaling, but Is Not Required for Bacterial Lipoprotein-Induced Tolerance , 2010, The Journal of Immunology.

[68]  S. Akira,et al.  The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors , 2010, Nature Immunology.

[69]  A. Margulis,et al.  IL-33 synergizes with IgE-dependent and IgE-independent agents to promote mast cell and basophil activation , 2010, Inflammation Research.

[70]  A. McKenzie,et al.  Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity , 2010, Nature.

[71]  T. van der Poll,et al.  Soluble ST2 plasma concentrations predict mortality in severe sepsis , 2010, Intensive Care Medicine.

[72]  I. McInnes,et al.  Disease-associated functions of IL-33: the new kid in the IL-1 family , 2010, Nature Reviews Immunology.

[73]  M. Hayakawa,et al.  ST2 gene expression is proliferation-dependent and its ligand, IL-33, induces inflammatory reaction in endothelial cells , 2010, Molecular and Cellular Biochemistry.

[74]  I. McInnes,et al.  IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation1 , 2009, The Journal of Immunology.

[75]  Bo-Jeong Pyun,et al.  Interleukin-33 induces angiogenesis and vascular permeability through ST2/TRAF6-mediated endothelial nitric oxide production. , 2009, Blood.

[76]  J. Kanellopoulos,et al.  IL-33 Enhances Lipopolysaccharide-Induced Inflammatory Cytokine Production from Mouse Macrophages by Regulating Lipopolysaccharide Receptor Complex1 , 2009, The Journal of Immunology.

[77]  H. Kita,et al.  IL-33-activated dendritic cells induce an atypical TH2-type response. , 2009, The Journal of allergy and clinical immunology.

[78]  P. Gourdy,et al.  The pro‐Th2 cytokine IL‐33 directly interacts with invariant NKT and NK cells to induce IFN‐γ production , 2009, European journal of immunology.

[79]  C. Dahinden,et al.  Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. , 2009, Blood.

[80]  M. Teixeira,et al.  IL-33 induced Ag-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4 , 2008, The Journal of Immunology.

[81]  K. Ohta,et al.  An IL-1 Cytokine Member, IL-33, Induces Human Basophil Activation via Its ST2 Receptor1 , 2008, The Journal of Immunology.

[82]  J. Girard,et al.  The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’? , 2008, PloS one.

[83]  Peter A. Ward,et al.  Harmful molecular mechanisms in sepsis , 2008, Nature Reviews Immunology.

[84]  L. Roussel,et al.  Molecular mimicry between IL‐33 and KSHV for attachment to chromatin through the H2A–H2B acidic pocket , 2008, EMBO reports.

[85]  M. Hayakawa,et al.  TRAF6 is a critical signal transducer in IL-33 signaling pathway. , 2008, Cellular signalling.

[86]  K. Ohta,et al.  Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils , 2008, Laboratory Investigation.

[87]  Dirk E. Smith,et al.  IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells. , 2008, International immunology.

[88]  H. Kita,et al.  A novel IL-1 family cytokine, IL-33, potently activates human eosinophils. , 2008, The Journal of allergy and clinical immunology.

[89]  C. Chung,et al.  Regulatory T cell populations in sepsis and trauma , 2008, Journal of leukocyte biology.

[90]  Ashley M. Miller,et al.  IL-33 reduces the development of atherosclerosis , 2008, The Journal of experimental medicine.

[91]  O. Donzé,et al.  Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells. , 2007, Cytokine.

[92]  M. Huber,et al.  IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells , 2007, Proceedings of the National Academy of Sciences.

[93]  S. Opal.  The host response to endotoxin, antilipopolysaccharide strategies, and the management of severe sepsis. , 2007, International journal of medical microbiology : IJMM.

[94]  Dirk E. Smith,et al.  Cutting Edge: The ST2 Ligand IL-33 Potently Activates and Drives Maturation of Human Mast Cells1 , 2007, The Journal of Immunology.

[95]  S. Galli,et al.  IL-33 can promote survival, adhesion and cytokine production in human mast cells , 2007, Laboratory Investigation.

[96]  Richard T. Lee,et al.  IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system. , 2007, The Journal of clinical investigation.

[97]  R. D. Hatton,et al.  IL-17 family cytokines and the expanding diversity of effector T cell lineages. , 2007, Annual review of immunology.

[98]  R. Hotchkiss,et al.  Apoptosis and caspases regulate death and inflammation in sepsis , 2006, Nature Reviews Immunology.

[99]  M. Hayakawa,et al.  ST2 suppresses IL-6 production via the inhibition of IkappaB degradation induced by the LPS signal in THP-1 cells. , 2006, Biochemical and biophysical research communications.

[100]  J Fernando Bazan,et al.  IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. , 2005, Immunity.

[101]  J. Younger,et al.  HARMFUL AND PROTECTIVE ROLES OF NEUTROPHILS IN SEPSIS , 2005, Shock.

[102]  Shizuo Akira,et al.  Toll-like receptor signalling , 2004, Nature Reviews Immunology.

[103]  F. Liew,et al.  ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance , 2004, Nature Immunology.

[104]  A. Spittler,et al.  Increased levels of soluble ST2 protein and IgG1 production in patients with sepsis and trauma , 2004, Intensive Care Medicine.

[105]  Shizuo Akira,et al.  Toll-like Receptor Signaling* , 2003, Journal of Biological Chemistry.

[106]  S. Tominaga,et al.  The increase in serum soluble ST2 protein upon acute exacerbation of idiopathic pulmonary fibrosis. , 2003, Chest.

[107]  E. S. Baekkevold,et al.  Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules. , 2003, The American journal of pathology.

[108]  S. Lakhani,et al.  Toll-like receptor signaling in sepsis , 2003, Current opinion in pediatrics.

[109]  Richard T. Lee,et al.  Identification of Serum Soluble ST2 Receptor as a Novel Heart Failure Biomarker , 2003, Circulation.

[110]  Jonathan Cohen.  The immunopathogenesis of sepsis , 2002, Nature.

[111]  Y. Sugiyama,et al.  Expression and function of the ST2 gene in a murine model of allergic airway inflammation , 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[112]  D. Smith,et al.  A survey of non-depolarising muscle relaxants used in cardiac anaesthesia and surgery , 2002, Critical Care.

[113]  S. Opal,et al.  Bench-to-bedside review: Toll-like receptors and their role in septic shock , 2002, Critical care.

[114]  L. Moldawer,et al.  SEPSIS SYNDROMES: UNDERSTANDING THE ROLE OF INNATE AND ACQUIRED IMMUNITY , 2001, Shock.

[115]  S. Tominaga,et al.  Elevated soluble ST2 protein levels in sera of patients with asthma with an acute exacerbation. , 2001, American journal of respiratory and critical care medicine.

[116]  S. Tominaga,et al.  Identification of human ST2 protein in the sera of patients with autoimmune diseases. , 2001, Biochemical and biophysical research communications.

[117]  M. Sweet,et al.  A Novel Pathway Regulating Lipopolysaccharide-Induced Shock by ST2/T1 Via Inhibition of Toll-Like Receptor 4 Expression1 , 2001, The Journal of Immunology.

[118]  S. Opal,et al.  Anti-inflammatory cytokines. , 2000, Chest.

[119]  Shinobu Tominaga.  A putative protein of a growth specific cDNA from BALB/C‐3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor , 1989, FEBS letters.

[120]  T. Hagelberg.  [Military medical research]. , 1951, Svenska lakartidningen.

[121]  Y. An,et al.  The immunoprotective activity of interleukin-33 in mouse model of cecal ligation and puncture-induced sepsis. , 2016, Immunology letters.

[122]  A. Karaoğlu,et al.  Diagnostic Value of Upar, IL-33, and ST2 Levels in Childhood Sepsis. , 2016, Clinical laboratory.

[123]  H. Turnquist,et al.  Expansion of Regulatory T Cells In Vitro and In Vivo by IL-33. , 2016, Methods in molecular biology.

[124]  A. McKenzie,et al.  Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity. , 2012, The Journal of allergy and clinical immunology.

[125]  J. Litzman,et al.  Soluble ST2 levels in patients with cardiogenic and septic shock are not predictors of mortality. , 2012, Experimental and clinical cardiology.

[126]  S. Zanotti,et al.  Severe Sepsis and Septic Shock , 2011 .

[127]  S. Nakae,et al.  IL-33 and IL-33 receptors in host defense and diseases. , 2010, Allergology international : official journal of the Japanese Society of Allergology.

[128]  T. van der Poll,et al.  Host-pathogen interactions in sepsis. , 2008, The Lancet. Infectious diseases.

[129]  Nevenka Laban-Gučeva,et al.  Serum concentrations of interleukin (IL-)1alpha, 1beta, 6 and tumor necrosis factor (TNF-) alpha in patients with thyroid eye disease (TED). , 2007, Medicinski arhiv.

[130]  M. Bhatia,et al.  Inflammatory mediators in sepsis: Cytokines, chemokines, adhesion molecules and gases , 2006 .