Deep learning approaches for natural product discovery from plant endophytic microbiomes
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[1] Peter D. Karp,et al. Pathway Tools version 23.0 update: software for pathway/genome informatics and systems biology , 2019, Briefings Bioinform..
[2] Uwe Ohler,et al. Deep learning for genomics using Janggu , 2020, Nature Communications.
[3] M. Abdelhamid,et al. Linking Endophytic Fungi to Medicinal Plants Therapeutic Activity. A Case Study on Asteraceae , 2020 .
[4] Hai-Wei Zhou,et al. Anti-cervical cancer activity of secondary metabolites of endophytic fungi from Ginkgo biloba. , 2020, Cancer biomarkers : section A of Disease markers.
[5] S. Kembel,et al. Adaptive matching between phyllosphere bacteria and their tree hosts in a neotropical forest , 2020, Microbiome.
[6] Byung-Kwan Cho,et al. Repurposing Modular Polyketide Synthases and Non-ribosomal Peptide Synthetases for Novel Chemical Biosynthesis , 2020, Frontiers in Molecular Biosciences.
[7] A. Siddique. Viruses of endophytic and pathogenic forest fungi , 2020, Virus Genes.
[8] J. Kalaitzis,et al. Genome mining of a fungal endophyte of Taxus yunnanensis (Chinese yew) leads to the discovery of a novel azaphilone polyketide, lijiquinone , 2020, Microbial biotechnology.
[9] L. Albarano,et al. Genome Mining as New Challenge in Natural Products Discovery , 2020, Marine drugs.
[10] Scott A. Walper,et al. Bacterial Membrane Vesicles as Mediators of Microbe – Microbe and Microbe – Host Community Interactions , 2020, Frontiers in Microbiology.
[11] A. Baten,et al. Genome and secretome analysis of jute endophyte Grammothele lineata strain SDL-CO-2015-1: Insights into its lignocellulolytic structure and secondary metabolite profile. , 2020, Genomics.
[12] D. Thakur,et al. Phylogenetic and Functional Characterization of Culturable Endophytic Actinobacteria Associated With Camellia spp. for Growth Promotion in Commercial Tea Cultivars , 2020, Frontiers in Microbiology.
[13] A. Brakhage,et al. Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin , 2020, eLife.
[14] P. Gundel,et al. Simulated folivory increases vertical transmission of fungal endophytes that deter herbivores and alter tolerance to herbivory in Poa autumnalis. , 2020, Annals of botany.
[15] S. Moineau,et al. Phage diversity, genomics and phylogeny , 2020, Nature Reviews Microbiology.
[16] Emma J. Chory,et al. A Deep Learning Approach to Antibiotic Discovery , 2020, Cell.
[17] Yongmei Li,et al. Unraveling the metabolite signature of citrus showing defense response towards Candidatus Liberibacter asiaticus after application of endophyte Bacillus subtilis L1-21. , 2020, Microbiological research.
[18] Gerald Maggiora,et al. The impact of chemoinformatics on drug discovery in the pharmaceutical industry , 2020, Expert opinion on drug discovery.
[19] E. Čellárová,et al. Computational screening of miRNAs and their targets in leaves of Hypericum spp. by transcriptome-mining: a pilot study , 2020, Planta.
[20] J. Harrison,et al. The diversity and distribution of endophytes across biomes, plant phylogeny, and host tissues-how far have we come and where do we go from here? , 2020, Environmental microbiology.
[21] J. van Staden,et al. A critical review on exploiting the pharmaceutical potential of plant endophytic fungi. , 2020, Biotechnology advances.
[22] Hideki Takahashi,et al. Virus Latency and the Impact on Plants , 2019, Front. Microbiol..
[23] Joseph N. Paulson,et al. Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome , 2019, Science.
[24] P. Zhu,et al. Advances in targeting and heterologous expression of genes involved in the synthesis of fungal secondary metabolites , 2019, RSC advances.
[25] R. Seidl,et al. Harnessing Deep Learning in Ecology: An Example Predicting Bark Beetle Outbreaks , 2019, Front. Plant Sci..
[26] J. Lipuma,et al. Loci Encoding Compounds Potentially Active against Drug-Resistant Pathogens amidst a Decreasing Pool of Novel Antibiotics , 2019, Applied and Environmental Microbiology.
[27] Mohammad Alanjary,et al. Applied evolution: phylogeny-based approaches in natural products research. , 2019, Natural product reports.
[28] A. Deutschbauer,et al. Genome-wide identification of Pseudomonas syringae genes required for fitness during colonization of the leaf surface and apoplast , 2019, Proceedings of the National Academy of Sciences.
[29] Danny A. Bitton,et al. A deep learning genome-mining strategy for biosynthetic gene cluster prediction , 2019, Nucleic acids research.
[30] M. Sitohy,et al. Restoring the Taxol biosynthetic machinery of Aspergillus terreus by Podocarpus gracilior Pilger microbiome, with retrieving the ribosome biogenesis proteins of WD40 superfamily , 2019, Scientific Reports.
[31] P. A. Caicedo,et al. Antioxidant activity of exo‐metabolites produced by Fusarium oxysporum: An endophytic fungus isolated from leaves of Otoba gracilipes , 2019, MicrobiologyOpen.
[32] F. Vinale,et al. The Shifting Mycotoxin Profiles of Endophytic Fusarium Strains: A Case Study , 2019, Agriculture.
[33] G. Ravikanth,et al. How and why do endophytes produce plant secondary metabolites? , 2019, Symbiosis.
[34] M. Kurina-Sanz,et al. Natural trypanocidal product produced by endophytic fungi through co-culturing , 2019, Folia Microbiologica.
[35] M. Seidl,et al. Chromatin-dependent regulation of secondary metabolite biosynthesis in fungi: is the picture complete? , 2019, FEMS microbiology reviews.
[36] C. Gutjahr,et al. Systems Biology of Plant-Microbiome Interactions. , 2019, Molecular plant.
[37] Ying Li,et al. Iso-Seq analysis of the Taxus cuspidata transcriptome reveals the complexity of Taxol biosynthesis , 2019, BMC Plant Biology.
[38] J. Koricheva,et al. Meta‐analysis of the role of entomopathogenic and unspecialized fungal endophytes as plant bodyguards , 2019, The New phytologist.
[39] Seokhwan Hwang,et al. Development of an interspecies interaction model: An experiment on Clostridium cadaveris and Clostridium sporogenes under anaerobic condition. , 2019, Journal of environmental management.
[40] S. Lee,et al. antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline , 2019, Nucleic Acids Res..
[41] J. Nielsen,et al. Comparative Transcriptome Analysis Shows Conserved Metabolic Regulation during Production of Secondary Metabolites in Filamentous Fungi , 2019, mSystems.
[42] Jiang,et al. Cross-Kingdom Small RNAs among Animals, Plants and Microbes , 2019, Cells.
[43] Elizabeth J. Skellam. Strategies for Engineering Natural Product Biosynthesis in Fungi. , 2019, Trends in biotechnology.
[44] Yun Jin,et al. A fungal milRNA mediates epigenetic repression of a virulence gene in Verticillium dahliae , 2019, Philosophical Transactions of the Royal Society B.
[45] M. Mano,et al. MicroRNAs at the Host-Bacteria Interface: Host Defense or Bacterial Offense. , 2019, Trends in microbiology.
[46] R. Pan,et al. Exploring Structural Diversity of Microbe Secondary Metabolites Using OSMAC Strategy: A Literature Review , 2019, Front. Microbiol..
[47] M. Zong,et al. Immune enhancement activity of a novel polysaccharide produced by Dendrobium officinale endophytic fungus Fusarium solani DO7 , 2019, Journal of Functional Foods.
[48] L. Blank,et al. Investigating metabolic interactions in a microbial co-culture through integrated modelling and experiments , 2019, bioRxiv.
[49] S. Riyaz-Ul-Hassan,et al. Endohyphal bacteria; the prokaryotic modulators of host fungal biology , 2019, Fungal Biology Reviews.
[50] Wenbo Liu,et al. Corrigendum: Powdery Mildews Are Characterized by Contracted Carbohydrate Metabolism and Diverse Effectors to Adapt to Obligate Biotrophic Lifestyle , 2018, Front. Microbiol..
[51] K. Davis,et al. A Genetics-Free Method for High-Throughput Discovery of Cryptic Microbial Metabolites , 2018, Nature Chemical Biology.
[52] J. Ludwig-Mller. Interplay between endophyte and host plant in the synthesis and modification of metabolites. , 2019, Endophyte biotechnology: potential for agriculture and pharmacology.
[53] A. Schouten. Saving resources: the exploitation of endophytes by plants for the biosynthesis of multi-functional defence compounds. , 2019, Endophyte biotechnology: potential for agriculture and pharmacology.
[54] A. Schouten. Endophytic fungi: definitions, diversity, distribution and their significance in plant life. , 2019, Endophyte biotechnology: potential for agriculture and pharmacology.
[55] M. Rashmi,et al. Secondary Metabolite Production by Endophytic Fungi: The Gene Clusters, Nature, and Expression , 2019, Reference Series in Phytochemistry.
[56] M. S. Mukhtar,et al. Systems Biology and Machine Learning in Plant-Pathogen Interactions. , 2019, Molecular plant-microbe interactions : MPMI.
[57] A. Shaytan,et al. Linking chromatin composition and structural dynamics at the nucleosome level. , 2019, Current opinion in structural biology.
[58] N. Keller. Fungal secondary metabolism: regulation, function and drug discovery , 2018, Nature Reviews Microbiology.
[59] J. Carlson,et al. Microbiome interactions shape host fitness , 2018, Proceedings of the National Academy of Sciences.
[60] A. Salamov,et al. Uncovering secondary metabolite evolution and biosynthesis using gene cluster networks and genetic dereplication , 2018, Scientific Reports.
[61] T. Liu,et al. Integrated microRNA and mRNA analysis in the pathogenic filamentous fungus Trichophyton rubrum , 2018, BMC Genomics.
[62] P. Proksch,et al. Epigenetic modification, co-culture and genomic methods for natural product discovery , 2018, Physical Sciences Reviews.
[63] N. Arora,et al. Multifaceted Interactions Between Endophytes and Plant: Developments and Prospects , 2018, Front. Microbiol..
[64] Huimin Zhao,et al. Activation of silent biosynthetic gene clusters using transcription factor decoys , 2018, Nature Chemical Biology.
[65] Daniel A. Jacobson,et al. Exploration of the Biosynthetic Potential of the Populus Microbiome , 2018, mSystems.
[66] Hao Wang,et al. RAVEN 2.0: A versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor , 2018, bioRxiv.
[67] Yihan Wu,et al. Recent advances in activating silent biosynthetic gene clusters in bacteria. , 2018, Current opinion in microbiology.
[68] Ingo Bauer,et al. A Class 1 Histone Deacetylase as Major Regulator of Secondary Metabolite Production in Aspergillus nidulans , 2018, Front. Microbiol..
[69] B. Baral,et al. Activation of microbial secondary metabolic pathways: Avenues and challenges , 2018, Synthetic and systems biotechnology.
[70] C. Schadt,et al. Phylogenomics Reveal the Dynamic Evolution of Fungal Nitric Oxide Reductases and Their Relationship to Secondary Metabolism , 2018, Genome biology and evolution.
[71] Xiang-Hua Wang,et al. Novel natural compounds from endophytic fungi with anticancer activity. , 2018, European journal of medicinal chemistry.
[72] H. Toju,et al. Beneficial associations between Brassicaceae plants and fungal endophytes under nutrient-limiting conditions: evolutionary origins and host-symbiont molecular mechanisms. , 2018, Current opinion in plant biology.
[73] M. Medema,et al. A standardized workflow for submitting data to the Minimum Information about a Biosynthetic Gene cluster (MIBiG) repository: prospects for research-based educational experiences , 2018, Standards in Genomic Sciences.
[74] Karthik Raman,et al. Enumerating all possible biosynthetic pathways in metabolic networks , 2018, Scientific Reports.
[75] Chunyuan Li,et al. Fusarihexins A and B: Novel Cyclic Hexadepsipeptides from the Mangrove Endophytic Fungus Fusarium sp. R5 with Antifungal Activities , 2018, Planta Medica.
[76] Akifumi S. Tanabe,et al. Network hubs in root-associated fungal metacommunities , 2018, Microbiome.
[77] Dana L. Carper,et al. Bacterial endophyte communities in Pinus flexilis are structured by host age, tissue type, and environmental factors , 2018, Plant and Soil.
[78] R. Milo,et al. The biomass distribution on Earth , 2018, Proceedings of the National Academy of Sciences.
[79] Jarosław Grządziel,et al. The identification and genetic diversity of endophytic bacteria isolated from selected crops , 2018, The Journal of Agricultural Science.
[80] V. Gupta,et al. Endophytic Fungi—Alternative Sources of Cytotoxic Compounds: A Review , 2018, Front. Pharmacol..
[81] Jingyun Fang,et al. Patterns of plant carbon, nitrogen, and phosphorus concentration in relation to productivity in China’s terrestrial ecosystems , 2018, Proceedings of the National Academy of Sciences.
[82] T. Wubet,et al. Direct comparison of culture-dependent and culture-independent molecular approaches reveal the diversity of fungal endophytic communities in stems of grapevine (Vitis vinifera) , 2018, Fungal Diversity.
[83] Diane O. Inglis,et al. HEx: A heterologous expression platform for the discovery of fungal natural products , 2018, Science Advances.
[84] R. Sorek,et al. Contemporary Phage Biology: From Classic Models to New Insights , 2018, Cell.
[85] H. Lou,et al. Structural Diversity and Biological Activities of Novel Secondary Metabolites from Endophytes , 2018, Molecules.
[86] Micheal C. Wilson,et al. Single-bacterial genomics validates rich and varied specialized metabolism of uncultivated Entotheonella sponge symbionts , 2018, Proceedings of the National Academy of Sciences.
[87] J. Maciá‐Vicente,et al. Facultative root-colonizing fungi dominate endophytic assemblages in roots of nonmycorrhizal Microthlaspi species. , 2018, The New phytologist.
[88] P. Poole,et al. Rhizobia: from saprophytes to endosymbionts , 2018, Nature Reviews Microbiology.
[89] R. Quinn,et al. Annual Review of Pharmacology and Toxicology Harnessing the Properties of Natural Products , 2017 .
[90] C. Hua,et al. Trans-Kingdom RNA Silencing in Plant-Fungal Pathogen Interactions. , 2017, Molecular plant.
[91] M. Rashmi,et al. Secondary Metabolite Production by Endophytic Fungi : The Gene Clusters , Nature , and Expression , 2018 .
[92] M. Krings,et al. Fungi and fungal interactions in the Rhynie chert: a review of the evidence, with the description of Perexiflasca tayloriana gen. et sp. nov.† , 2018, Philosophical Transactions of the Royal Society B: Biological Sciences.
[93] E. Brzuszkiewicz,et al. Comparative genome and phenotypic analysis of three Clostridioides difficile strains isolated from a single patient provide insight into multiple infection of C. difficile , 2018, BMC Genomics.
[94] C. Pieterse,et al. Inner Plant Values: Diversity, Colonization and Benefits from Endophytic Bacteria , 2017, Front. Microbiol..
[95] Huimin Zhao,et al. Breaking the silence: new strategies for discovering novel natural products. , 2017, Current opinion in biotechnology.
[96] Anwar Rayan,et al. Nature is the best source of anticancer drugs: Indexing natural products for their anticancer bioactivity , 2017, PloS one.
[97] Ying Huang,et al. Genetic Manipulation of the COP9 Signalosome Subunit PfCsnE Leads to the Discovery of Pestaloficins in Pestalotiopsis fici. , 2017, Organic letters.
[98] Robert Lücking,et al. Fungal Diversity Revisited: 2.2 to 3.8 Million Species , 2017, Microbiology spectrum.
[99] J. Stajich. Fungal Genomes and Insights into the Evolution of the Kingdom , 2017, Microbiology spectrum.
[100] M. Vainstein,et al. Genome-Wide Analysis of Secondary Metabolite Gene Clusters in Ophiostoma ulmi and Ophiostoma novo-ulmi Reveals a Fujikurin-Like Gene Cluster with a Putative Role in Infection , 2017, Front. Microbiol..
[101] O. Eriksson,et al. Specificity of fungal associations of Pyroleae and Monotropa hypopitys during germination and seedling development , 2017, Molecular ecology.
[102] T. Schwander,et al. Patterns and mechanisms in instances of endosymbiont‐induced parthenogenesis , 2017, Journal of evolutionary biology.
[103] William H. Gerwick,et al. Retrospective analysis of natural products provides insights for future discovery trends , 2017, Proceedings of the National Academy of Sciences.
[104] J. Lennon,et al. A macroecological theory of microbial biodiversity , 2017, Nature Ecology &Evolution.
[105] M. Anandaraj,et al. Endophytic actinobacteria: Diversity, secondary metabolism and mechanisms to unsilence biosynthetic gene clusters , 2017, Critical reviews in microbiology.
[106] Galen P. Miley,et al. A Scalable Platform to Identify Fungal Secondary Metabolites and Their Gene Clusters , 2017, Nature chemical biology.
[107] R. Malheiro,et al. Antimicrobial activity of endophytic fungi from olive tree leaves , 2017, World journal of microbiology & biotechnology.
[108] I-Min A. Chen,et al. IMG-ABC: new features for bacterial secondary metabolism analysis and targeted biosynthetic gene cluster discovery in thousands of microbial genomes , 2016, Nucleic Acids Res..
[109] V. Maheshwari,et al. Endophytes: Potential Source of Therapeutically Important Secondary Metabolites of Plant Origin , 2017 .
[110] D. Maheshwari. Endophytes: Biology and Biotechnology , 2017, Sustainable Development and Biodiversity.
[111] Richard H. Baltz,et al. Gifted microbes for genome mining and natural product discovery , 2017, Journal of Industrial Microbiology & Biotechnology.
[112] A. Chaubey,et al. An Insight into the Secondary Metabolism of Muscodor yucatanensis: Small-Molecule Epigenetic Modifiers Induce Expression of Secondary Metabolism-Related Genes and Production of New Metabolites in the Endophyte , 2017, Microbial Ecology.
[113] V. Barbe,et al. Modeling trophic dependencies and exchanges among insects’ bacterial symbionts in a host-simulated environment , 2016, bioRxiv.
[114] M. Afzal,et al. Ecology of bacterial endophytes associated with wetland plants growing in textile effluent for pollutant-degradation and plant growth-promotion potentials , 2016 .
[115] W. Carson,et al. Foliar bacteria and soil fertility mediate seedling performance: a new and cryptic dimension of niche differentiation. , 2016, Ecology.
[116] J. Wandji,et al. Anticancer and antibacterial secondary metabolites from the endophytic fungus Penicillium sp. CAM64 against multi-drug resistant Gram-negative bacteria. , 2016, African health sciences.
[117] P. Proksch,et al. Inducing secondary metabolite production by the endophytic fungus Chaetomium sp. through fungal–bacterial co-culture and epigenetic modification , 2016 .
[118] P. K. Agrawal,et al. Evaluation of bioactive secondary metabolites from endophytic fungus Pestalotiopsis neglecta BAB-5510 isolated from leaves of Cupressus torulosa D.Don , 2016, 3 Biotech.
[119] H. Tan,et al. A New Approach to Analyzing Endophytic Actinobacterial Population in the Roots of Banana Plants (Musa sp., AAA) , 2016 .
[120] M. Andersen,et al. Linker Flexibility Facilitates Module Exchange in Fungal Hybrid PKS-NRPS Engineering , 2016, PloS one.
[121] Georgios A. Pavlopoulos,et al. Uncovering Earth’s virome , 2016, Nature.
[122] A. Willis. Extrapolating abundance curves has no predictive power for estimating microbial biodiversity , 2016, Proceedings of the National Academy of Sciences.
[123] J. Lennon,et al. Reply to Willis: Powerful predictions of biodiversity from ecological models and scaling laws , 2016, Proceedings of the National Academy of Sciences.
[124] J. Flexas,et al. Alterations in primary and secondary metabolism in Vitis vinifera 'Malvasía de Banyalbufar' upon infection with Grapevine leafroll-associated virus 3. , 2016, Physiologia plantarum.
[125] C. Llave. Dynamic cross-talk between host primary metabolism and viruses during infections in plants. , 2016, Current opinion in virology.
[126] M. Jia,et al. A Friendly Relationship between Endophytic Fungi and Medicinal Plants: A Systematic Review , 2016, Front. Microbiol..
[127] J. Lennon,et al. Scaling laws predict global microbial diversity , 2016, Proceedings of the National Academy of Sciences.
[128] J. Soltani,et al. Endohyphal bacteria from fungal endophytes of the Mediterranean cypress (Cupressus sempervirens) exhibit in vitro bioactivity , 2016 .
[129] Marnix H Medema,et al. Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products. , 2016, Fungal genetics and biology : FG & B.
[130] David A. Baltrus,et al. Absence of genome reduction in diverse, facultative endohyphal bacteria , 2016, bioRxiv.
[131] A. Arnold,et al. Isolation of Endohyphal Bacteria from Foliar Ascomycota and In Vitro Establishment of Their Symbiotic Associations , 2016, Applied and Environmental Microbiology.
[132] D. Nuss,et al. Engineering super mycovirus donor strains of chestnut blight fungus by systematic disruption of multilocus vic genes , 2016, Proceedings of the National Academy of Sciences.
[133] D. Newman,et al. Natural Products as Sources of New Drugs from 1981 to 2014. , 2016, Journal of natural products.
[134] A. Hemerly,et al. Nice to meet you: genetic, epigenetic and metabolic controls of plant perception of beneficial associative and endophytic diazotrophic bacteria in non-leguminous plants , 2016, Plant Molecular Biology.
[135] Detlef Weigel,et al. Microbial Hub Taxa Link Host and Abiotic Factors to Plant Microbiome Variation , 2016, PLoS biology.
[136] M. Jia,et al. Endophytic fungi with antitumor activities: Their occurrence and anticancer compounds , 2014, Critical reviews in microbiology.
[137] P. Mariani,et al. Microbiome profiling in fresh-cut products , 2015 .
[138] A. Venugopalan,et al. Endophytes as in vitro production platforms of high value plant secondary metabolites. , 2015, Biotechnology advances.
[139] Kook Hyung Kim,et al. Five Questions about Mycoviruses , 2015, PLoS pathogens.
[140] Carla S. Jones,et al. Minimum Information about a Biosynthetic Gene cluster. , 2015, Nature chemical biology.
[141] Mingshu Cao,et al. A QTL analysis of host plant effects on fungal endophyte biomass and alkaloid expression in perennial ryegrass , 2015, Molecular Breeding.
[142] G. Challis,et al. Discovery of microbial natural products by activation of silent biosynthetic gene clusters , 2015, Nature Reviews Microbiology.
[143] E. Bedmar,et al. Bacterial Associations with Legumes , 2015 .
[144] Philippe Vandenkoornhuyse,et al. The importance of the microbiome of the plant holobiont. , 2015, The New phytologist.
[145] E. Radhakrishnan,et al. Effect of endophytic Bacillus sp. from selected medicinal plants on growth promotion and diosgenin production in Trigonella foenum-graecum , 2015, Plant Cell, Tissue and Organ Culture (PCTOC).
[146] O. Kayser,et al. Implications of endophyte-plant crosstalk in light of quorum responses for plant biotechnology , 2015, Applied Microbiology and Biotechnology.
[147] Nowsheen Shameem,et al. Fungal endophytes as prolific source of phytochemicals and other bioactive natural products: A review. , 2015, Microbial pathogenesis.
[148] M. Roossinck. Plants, viruses and the environment: Ecology and mutualism. , 2015, Virology.
[149] N. Suzuki,et al. 50-plus years of fungal viruses. , 2015, Virology.
[150] J. Fischer,et al. Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters , 2015, Front. Microbiol..
[151] Y. Kraepiel,et al. A straightforward and reliable method for bacterial in planta transcriptomics: application to the Dickeya dadantii/Arabidopsis thaliana pathosystem. , 2015, The Plant journal : for cell and molecular biology.
[152] J. Ludwig-Müller. Plants and endophytes: equal partners in secondary metabolite production? , 2015, Biotechnology Letters.
[153] M. Metsä-Ketelä,et al. Targeted activation of silent natural product biosynthesis pathways by reporter-guided mutant selection. , 2015, Metabolic engineering.
[154] U. Mortensen,et al. Heterologous production of fungal secondary metabolites in Aspergilli , 2015, Front. Microbiol..
[155] Mathias Dunkel,et al. Super Natural II—a database of natural products , 2014, Nucleic Acids Res..
[156] S. Ekesi,et al. Colonization of Onions by Endophytic Fungi and Their Impacts on the Biology of Thrips tabaci , 2014, PloS one.
[157] G. Bills,et al. New insights into the echinocandins and other fungal non-ribosomal peptides and peptaibiotics. , 2014, Natural product reports.
[158] H. Thordal-Christensen,et al. Trans-kingdom Cross-Talk: Small RNAs on the Move , 2014, PLoS genetics.
[159] D. Jiāng,et al. New insights into mycoviruses and exploration for the biological control of crop fungal diseases. , 2014, Annual review of phytopathology.
[160] Roger G. Linington,et al. Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters , 2014, Cell.
[161] F. Trognitz,et al. Metabolic potential of endophytic bacteria , 2014, Current opinion in biotechnology.
[162] Satpal Singh,et al. Rethinking production of Taxol® (paclitaxel) using endophyte biotechnology. , 2014, Trends in biotechnology.
[163] John B. O. Mitchell. Machine learning methods in chemoinformatics , 2014, Wiley interdisciplinary reviews. Computational molecular science.
[164] G. Hoffman. Correction: Correcting for Population Structure and Kinship Using the Linear Mixed Model: Theory and Extensions , 2013, PloS one.
[165] L. Espindola,et al. Antimicrobial and cytotoxic secondary metabolites from tropical leaf endophytes: Isolation of antibacterial agent pyrrocidine C from Lewia infectoria SNB-GTC2402. , 2013, Phytochemistry.
[166] A. Arnold,et al. Endohyphal Bacterium Enhances Production of Indole-3-Acetic Acid by a Foliar Fungal Endophyte , 2013, PloS one.
[167] W. Holben,et al. Bacterial endophytes enhance competition by invasive plants. , 2013, American journal of botany.
[168] Pierre Baldi,et al. Deep Architectures and Deep Learning in Chemoinformatics: The Prediction of Aqueous Solubility for Drug-Like Molecules , 2013, J. Chem. Inf. Model..
[169] P. Proksch,et al. Fungal endophytes - secret producers of bioactive plant metabolites. , 2013, Die Pharmazie.
[170] M. Spiteller,et al. Untapped mutualistic paradigms linking host plant and endophytic fungal production of similar bioactive secondary metabolites. , 2013, Phytochemistry.
[171] E. Prinsen,et al. Distribution of the cardiotoxin pavettamine in the coffee family (Rubiaceae) and its significance for gousiekte, a fatal poisoning of ruminants. , 2013, Plant physiology and biochemistry : PPB.
[172] Martha B. Arnaud,et al. Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae , 2013, BMC Microbiology.
[173] Intawat Nookaew,et al. The RAVEN Toolbox and Its Use for Generating a Genome-scale Metabolic Model for Penicillium chrysogenum , 2013, PLoS Comput. Biol..
[174] J. Leveau,et al. Isolation of Arthrobacter species from the phyllosphere and demonstration of their epiphytic fitness , 2013, MicrobiologyOpen.
[175] M. Raizada,et al. Interactions between Co-Habitating fungi Elicit Synthesis of Taxol from an Endophytic Fungus in Host Taxus Plants , 2012, Front. Microbio..
[176] Axel A. Brakhage,et al. Regulation of fungal secondary metabolism , 2012, Nature Reviews Microbiology.
[177] Nobuyuki Fujita,et al. DoBISCUIT: a database of secondary metabolite biosynthetic gene clusters , 2012, Nucleic Acids Res..
[178] Kyle R. Conway,et al. ClusterMine360: a database of microbial PKS/NRPS biosynthesis , 2012, Nucleic Acids Res..
[179] M. Roossinck,et al. Multiplexed interactions: viruses of endophytic fungi. , 2013, Advances in virus research.
[180] Mikael R. Andersen,et al. Accurate prediction of secondary metabolite gene clusters in filamentous fungi , 2012, Proceedings of the National Academy of Sciences.
[181] S. Kaul,et al. Endophytic fungi from medicinal plants: a treasure hunt for bioactive metabolites , 2012, Phytochemistry Reviews.
[182] J. V. van Elsas,et al. Endophytic bacterial communities in three arctic plants from low arctic fell tundra are cold-adapted and host-plant specific. , 2012, FEMS microbiology ecology.
[183] L. Eberl,et al. The eroded genome of a Psychotria leaf symbiont: hypotheses about lifestyle and interactions with its plant host. , 2012, Environmental microbiology.
[184] Simon P. Wilson,et al. Predicting total global species richness using rates of species description and estimates of taxonomic effort. , 2012, Systematic biology.
[185] In-Jung Lee,et al. Endophytic Fungi Produce Gibberellins and Indoleacetic Acid and Promotes Host-Plant Growth during Stress , 2012, Molecules.
[186] M. Pärtel,et al. Plant species richness: the world records , 2012 .
[187] F. Chang,et al. Highly oxidized ergosterols and isariotin analogs from an entomopathogenic fungus, Gibellula formosana, cultivated in the presence of epigenetic modifying agents , 2012 .
[188] J. Strauss,et al. The chromatin code of fungal secondary metabolite gene clusters , 2012, Applied Microbiology and Biotechnology.
[189] J. Raes,et al. Microbial interactions: from networks to models , 2012, Nature Reviews Microbiology.
[190] A. M. Gonzalez,et al. Compounds derived from endophytes: a review of phytochemistry and pharmacology. , 2012, Current medicinal chemistry.
[191] Ute Roessner,et al. A Historical Overview of Natural Products in Drug Discovery , 2012, Metabolites.
[192] W. Bains,et al. A combinatorial approach to biochemical space: description and application to the redox distribution of metabolism. , 2012, Astrobiology.
[193] V. Venturi,et al. Incoming pathogens team up with harmless 'resident' bacteria. , 2012, Trends in microbiology.
[194] M. Roossinck,et al. Are communities of microbial symbionts more diverse than communities of macrobial hosts? , 2012, Fungal biology.
[195] Hongyan Zhu,et al. Symbiosis specificity in the legume – rhizobial mutualism , 2012, Cellular microbiology.
[196] Peter D. Karp,et al. Construction and completion of flux balance models from pathway databases , 2012, Bioinform..
[197] R. Krska,et al. Heterochromatin influences the secondary metabolite profile in the plant pathogen Fusarium graminearum , 2012, Fungal genetics and biology : FG & B.
[198] Soizic Prado,et al. Diversity and Ecological Significance of Fungal Endophyte Natural Products , 2012 .
[199] G. Turner,et al. Fungal Secondary Metabolism , 2012, Methods in Molecular Biology.
[200] C. Rosa,et al. Endophytic Fungi of Tropical Forests: A Promising Source of Bioactive Prototype Molecules for the Treatment of Neglected Diseases , 2011 .
[201] S. Ghabrial,et al. A novel mycovirus closely related to hypoviruses that infects the plant pathogenic fungus Sclerotinia sclerotiorum. , 2011, Virology.
[202] Andrea Porras‐Alfaro,et al. Hidden fungi, emergent properties: endophytes and microbiomes. , 2011, Annual review of phytopathology.
[203] Jingyan Gu,et al. Antiviral isoindolone derivatives from an endophytic fungus Emericella sp. associated with Aegiceras corniculatum. , 2011, Phytochemistry.
[204] Kai Blin,et al. antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences , 2011, Nucleic Acids Res..
[205] P. Proksch,et al. Fungal endophytes: unique plant inhabitants with great promises , 2011, Applied Microbiology and Biotechnology.
[206] E. Smets,et al. Endophytic Bacteria in Toxic South African Plants: Identification, Phylogeny and Possible Involvement in Gousiekte , 2011, PloS one.
[207] M. Wingfield,et al. Characterization of a novel dsRNA element in the pine endophytic fungus Diplodia scrobiculata , 2011, Archives of Virology.
[208] M. Blackwell. The fungi: 1, 2, 3 ... 5.1 million species? , 2011, American journal of botany.
[209] M. Cox,et al. What triggers grass endophytes to switch from mutualism to pathogenism? , 2011, Plant science : an international journal of experimental plant biology.
[210] M. Roossinck. The good viruses: viral mutualistic symbioses , 2011, Nature Reviews Microbiology.
[211] G. Pastore,et al. The Use of Endophytes to Obtain Bioactive Compounds and Their Application in Biotransformation Process , 2010, Biotechnology research international.
[212] H. Izumi. Diversity of Endophytic Bacteria in Forest Trees , 2011 .
[213] Axel A Brakhage,et al. Fungal secondary metabolites - strategies to activate silent gene clusters. , 2011, Fungal genetics and biology : FG & B.
[214] Wenjun Li,et al. Biodiversity, bioactive natural products and biotechnological potential of plant-associated endophytic actinobacteria , 2011, Applied Microbiology and Biotechnology.
[215] R. Jeewon,et al. Endophytic Pestalotiopsis species associated with plants of Palmae, Rhizophoraceae, Planchonellae and Podocarpaceae in Hainan, China , 2010 .
[216] E. Favela-Torres,et al. A comparative study of Taxol production in liquid and solid‐state fermentation with Nigrospora sp. a fungus isolated from Taxus globosa , 2010, Journal of applied microbiology.
[217] Ji He,et al. Teasing apart a three-way symbiosis: transcriptome analyses of Curvularia protuberata in response to viral infection and heat stress. , 2010, Biochemical and biophysical research communications.
[218] D. Haft,et al. SMURF: Genomic mapping of fungal secondary metabolite clusters. , 2010, Fungal genetics and biology : FG & B.
[219] M. Roossinck. Lifestyles of plant viruses , 2010, Philosophical Transactions of the Royal Society B: Biological Sciences.
[220] A. Arnold,et al. Diverse Bacteria Inhabit Living Hyphae of Phylogenetically Diverse Fungal Endophytes , 2010, Applied and Environmental Microbiology.
[221] James Francis White,et al. Is plant endophyte-mediated defensive mutualism the result of oxidative stress protection? , 2010, Physiologia plantarum.
[222] K. Tang,et al. A review: recent advances and future prospects of taxol-producing endophytic fungi , 2010, Applied Microbiology and Biotechnology.
[223] A. Carroll,et al. Pestalactams A-C: novel caprolactams from the endophytic fungus Pestalotiopsis sp. , 2010, Organic & biomolecular chemistry.
[224] P. Proksch,et al. Methods for isolation of marine-derived endophytic fungi and their bioactive secondary products , 2010, Nature Protocols.
[225] F. Pedrosa,et al. Diversity of endophytic bacteria in Brazilian sugarcane. , 2010, Genetics and molecular research : GMR.
[226] Oliver Kayser,et al. Taxomyces andreanae: a presumed paclitaxel producer demystified? , 2009, Planta medica.
[227] N. Lorenz,et al. The ergot alkaloid gene cluster: functional analyses and evolutionary aspects. , 2009, Phytochemistry.
[228] P. Thomas,et al. Endophytic Bacteria Associated with Growing Shoot Tips of Banana (Musa sp.) cv. Grand Naine and the Affinity of Endophytes to the Host , 2009, Microbial Ecology.
[229] C. Hertweck,et al. Triggering cryptic natural product biosynthesis in microorganisms. , 2009, Organic & biomolecular chemistry.
[230] A. Arnold,et al. Fungal endophytes: diversity and functional roles. , 2009, The New phytologist.
[231] J. Muthumary,et al. A Novel Endophytic Taxol-Producing Fungus Chaetomella raphigera Isolated From a Medicinal Plant, Terminalia arjuna , 2009, Applied biochemistry and biotechnology.
[232] F. Sasse,et al. Fungal endophytes and bioprospecting , 2009 .
[233] G. Challis,et al. 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining , 2008, Proceedings of the National Academy of Sciences.
[234] J. Zucko,et al. ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures , 2008, Nucleic acids research.
[235] C. Tseng,et al. Cloning and characterization of monacolin K biosynthetic gene cluster from Monascus pilosus. , 2008, Journal of agricultural and food chemistry.
[236] H. J. Woerdenbag,et al. Endophytes: exploiting biodiversity for the improvement of natural product-based drug discovery , 2008 .
[237] D. Sinclair,et al. Xenohormesis: Sensing the Chemical Cues of Other Species , 2008, Cell.
[238] Yong-guan Zhu,et al. Positive correlation between soil bacterial metabolic and plant species diversity and bacterial and fungal diversity in a vegetation succession on Karst , 2008, Plant and Soil.
[239] K. Tang,et al. Bioactive natural products from endophytes: A review , 2008, Applied Biochemistry and Microbiology.
[240] M. Spiteller,et al. An endophytic fungus from Hypericum perforatum that produces hypericin. , 2008, Journal of natural products.
[241] Xiuzhu Dong,et al. Endophytic Bacterial Diversity in Rice (Oryza sativa L.) Roots Estimated by 16S rDNA Sequence Analysis , 2008, Microbial Ecology.
[242] Xuemin Zhang,et al. Evidence that RNA silencing functions as an antiviral defense mechanism in fungi , 2007, Proceedings of the National Academy of Sciences.
[243] M. Tribus,et al. Histone Deacetylase Activity Regulates Chemical Diversity in Aspergillus , 2007, Eukaryotic Cell.
[244] D. Hoffmeister,et al. Natural products of filamentous fungi: enzymes, genes, and their regulation. , 2007, Natural product reports.
[245] D. Stahl,et al. Metabolic modeling of a mutualistic microbial community , 2007, Molecular systems biology.
[246] B. Scott,et al. A Complex Ergovaline Gene Cluster in Epichloë Endophytes of Grasses , 2007, Applied and Environmental Microbiology.
[247] F. Lutzoni,et al. Phylogenetic relationships, host affinity, and geographic structure of boreal and arctic endophytes from three major plant lineages. , 2007, Molecular phylogenetics and evolution.
[248] R. Redman,et al. A Virus in a Fungus in a Plant: Three-Way Symbiosis Required for Thermal Tolerance , 2007, Science.
[249] G. Spangenberg,et al. A complex gene cluster for indole-diterpene biosynthesis in the grass endophyte Neotyphodium lolii. , 2006, Fungal genetics and biology : FG & B.
[250] R. Hückelhoven,et al. Endophyte or parasite--what decides? , 2006, Current opinion in plant biology.
[251] E. Martínez-Romero,et al. Bacterial endophytes and their interactions with hosts. , 2006, Molecular plant-microbe interactions : MPMI.
[252] M. Tarkka,et al. Auxofuran, a Novel Metabolite That Stimulates the Growth of Fly Agaric, Is Produced by the Mycorrhiza Helper Bacterium Streptomyces Strain AcH 505 , 2006, Applied and Environmental Microbiology.
[253] János Bérdy,et al. Bioactive microbial metabolites. , 2005, The Journal of antibiotics.
[254] M. Arakawa,et al. A Reovirus Causes Hypovirulence of Rosellinia necatrix. , 2004, Phytopathology.
[255] J. Stelling,et al. Combinatorial Complexity of Pathway Analysis in Metabolic Networks , 2004, Molecular Biology Reports.
[256] G. Strobel. Endophytes as sources of bioactive products. , 2003, Microbes and infection.
[257] Peter Vandamme,et al. 'Candidatus glomeribacter gigasporarum' gen. nov., sp. nov., an endosymbiont of arbuscular mycorrhizal fungi. , 2003, International journal of systematic and evolutionary microbiology.
[258] Hilde van der Togt,et al. Publisher's Note , 2003, J. Netw. Comput. Appl..
[259] B. Schulz,et al. Endophytic fungi: a source of novel biologically active secondary metabolites * * Paper presented at , 2002 .
[260] Axel Zeeck,et al. Big Effects from Small Changes: Possible Ways to Explore Nature's Chemical Diversity , 2002, Chembiochem : a European journal of chemical biology.
[261] A. Arnold,et al. Fungal endophytes in dicotyledonous neotropical trees: patterns of abundance and diversity , 2001 .
[262] C. Young,et al. Elimination of ergovaline from a grass–Neotyphodium endophyte symbiosis by genetic modification of the endophyte , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[263] Z. Zheng,et al. Antitumor and antifungal activities in endophytic fungi isolated from pharmaceutical plants Taxus mairei, Cephalataxus fortunei and Torreya grandis. , 2001, FEMS immunology and medical microbiology.
[264] D. Redecker,et al. Glomalean fungi from the Ordovician. , 2000, Science.
[265] P. Coley,et al. Are tropical fungal endophytes hyperdiverse , 2000 .
[266] I. Chapela,et al. Potential of fungi in the discovery of novel, low-molecular weight pharmaceuticals. , 1994, Biotechnology.
[267] V. Gullo. The discovery of natural products with therapeutic potential. , 1994, Biotechnology.
[268] A. Stierle,et al. Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew. , 1993, Science.
[269] R. M. Macdonald,et al. THE OCCURRENCE OF BACTERIUM‐LIKE ORGANELLES IN VESICULAR‐ARBUSCULAR MYCORRHIZAL FUNGI , 1982 .
[270] F. W. Preston. The Commonness, And Rarity, of Species , 1948 .