Clinical Results of Platelet-Rich Plasma for Partial Thickness Rotator Cuff Tears: A Case Series.

Partial thickness rotator cuff tears (PTRCTs) are a common pathology among shoulder disorders in people over 50 years. Treatment of PTRCTs remains controversial. Most studies on the treatment of PTRCTs have explained surgical techniques or outcomes; few studies have centralized on the conservative and new management of PTRCTs, like treatment with Platelet-rich plasma (PRP). These case series study have been conducted on Platelet-rich plasma (PRP) injection, as a concentrated source of cytokines that can stimulate healing of soft tissue. PRP injection showed positive effect on improving PTRCTs complains. This method improved pain, function, DASH score and shoulder joint range motion in. Because of PRP products are safe and easy to prepare and apply, and also according to improving patient's condition, this method can be used to treat PTRCTs.

[1]  T. Ackland,et al.  Do Postoperative Platelet-Rich Plasma Injections Accelerate Early Tendon Healing and Functional Recovery After Arthroscopic Supraspinatus Repair? A Randomized Controlled Trial , 2017 .

[2]  Chun-jiang Fu,et al.  Evaluation of platelet-rich plasma and fibrin matrix to assist in healing and repair of rotator cuff injuries: a systematic review and meta-analysis , 2017, Clinical rehabilitation.

[3]  Peter D. Fabricant,et al.  Utilization of Platelet-Rich Plasma for Musculoskeletal Injuries , 2016, Orthopaedic journal of sports medicine.

[4]  K. Yoon,et al.  Corrigendum. Platelet-rich plasma for arthroscopic repair of medium to large rotator cuff tears: a randomized controlled trial. , 2016, The American journal of sports medicine.

[5]  N. Maffulli,et al.  Muscle and tendon injuries: the role of biological interventions to promote and assist healing and recovery. , 2015, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[6]  P. Zhang,et al.  Platelet-rich plasma in arthroscopic rotator cuff repair: a meta-analysis of randomized controlled trials. , 2015, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[7]  A. Carr,et al.  Advances in biology and mechanics of rotator cuff repair , 2015, Knee Surgery, Sports Traumatology, Arthroscopy.

[8]  G. Banfi,et al.  Regenerative Medicine in Rotator Cuff Injuries , 2014, BioMed research international.

[9]  S. Rodeo,et al.  The basic science behind biologic augmentation of tendon-bone healing: a scientific review. , 2014, Instructional course lectures.

[10]  A. Carr,et al.  PARot – assessing platelet-rich plasma plus arthroscopic subacromial decompression in the treatment of rotator cuff tendinopathy: study protocol for a randomized controlled trial , 2013, Trials.

[11]  R. Barco,et al.  Platelet-rich fibrin in arthroscopic repair of massive rotator cuff tears: a prospective randomized pilot clinical trial. , 2013, Acta orthopaedica Belgica.

[12]  Anjuman-i Jarrāḥān-i Urtūpidī-i Īrān,et al.  The archives of bone and joint surgery , 2013 .

[13]  D. Mainardb,et al.  Current concept for the use of PRP in arthroscopic surgery , 2013 .

[14]  M. Lenza,et al.  Platelet-rich therapies for musculoskeletal soft tissue injuries. , 2013, The Cochrane database of systematic reviews.

[15]  P. Tonino,et al.  The Biomechanical and Histologic Effects of Platelet-Rich Plasma on Rat Rotator Cuff Repairs , 2012, The American journal of sports medicine.

[16]  N. Simunovic,et al.  Efficacy of autologous platelet-rich plasma use for orthopaedic indications: a meta-analysis. , 2012, The Journal of bone and joint surgery. American volume.

[17]  A. Watts,et al.  Cell- and gene-based approaches to tendon regeneration. , 2012, Journal of shoulder and elbow surgery.

[18]  V. Denaro,et al.  Tissue Engineering for Rotator Cuff Repair: An Evidence-Based Systematic Review , 2011, Stem cells international.

[19]  F. Barber,et al.  Platelet-Rich Plasma Products in Sports Medicine , 2011, The Physician and sportsmedicine.

[20]  S. Snyder,et al.  Rotator cuff repair healing influenced by platelet-rich plasma construct augmentation. , 2011, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[21]  M. Hendry,et al.  A Systematic Review of the Use of Platelet-Rich Plasma in Sports Medicine as a New Treatment for Tendon and Ligament Injuries , 2011, Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine.

[22]  Jeffrey Yao,et al.  Delivered growth factor therapy to improve healing after rotator cuff repair , 2010, Stem cells and cloning : advances and applications.

[23]  J. Sperling,et al.  Strategies in Biologic Augmentation of Rotator Cuff Repair: A Review , 2010, Clinical orthopaedics and related research.

[24]  P. Maniscalco,et al.  The "Cascade" membrane: a new PRP device for tendon ruptures. Description and case report on rotator cuff tendon. , 2008, Acta bio-medica : Atenei Parmensis.

[25]  N. Maffulli,et al.  Autologous platelet rich plasma for arthroscopic rotator cuff repair. A pilot study , 2008, Disability and rehabilitation.

[26]  E. Anitua Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants. , 1999, The International journal of oral & maxillofacial implants.

[27]  H Ellman,et al.  Diagnosis and treatment of incomplete rotator cuff tears. , 1990, Clinical orthopaedics and related research.