Abdominelle Sonografie bei Patienten mit Diabetes mellitus. Teil 1: Leber

Zusammenfassung Die abdominelle Sonografie ist geeignet, Folgeschäden und Begleiterkrankungen des Diabetes mellitus an Leber, Pankreas, Nieren, Gastrointestinaltrakt und abdominell-retroperitonealen arteriellen Gefäßen zu erfassen und zu verfolgen. Darüber hinaus ermöglicht die abdominelle Sonografie die Erfassung von Pankreas- und Lebererkrankungen, die ursächlich für einen Diabetes mellitus sind. Auf der Grundlage einer systematischen Literaturanalyse wird in einer 3-teiligen Übersichtsarbeit der Stellenwert der abdominellen Sonografie bei Patienten mit Diabetes mellitus dargestellt. Teil 1 beschreibt die Relevanz und konkrete Befunde sonografischer Methoden für die Diagnostik der hepatischen Manifestationen und Komplikationen des Diabetes mellitus.

[1]  Anthony Gamst,et al.  Noninvasive Diagnosis of Nonalcoholic Fatty Liver Disease and Quantification of Liver Fat Using a New Quantitative Ultrasound Technique. , 2015, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[2]  B. Wang,et al.  Effect of type 2 diabetes mellitus on the risk for hepatocellular carcinoma in chronic liver diseases: a meta-analysis of cohort studies , 2015, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[3]  N. B. Topal,et al.  Effects of fat accumulation in the liver on hemodynamic variables assessed by doppler ultrasonography , 2014, Journal of clinical ultrasound : JCU.

[4]  F. Nascimbeni,et al.  Performance and limitations of steatosis biomarkers in patients with nonalcoholic fatty liver disease , 2014, Alimentary pharmacology & therapeutics.

[5]  C. Dietrich,et al.  Ultrasound in Rare Diffuse Liver Disease , 2014, Zeitschrift für Gastroenterologie.

[6]  Ding‐Shinn Chen,et al.  Increased risk of cirrhosis and its decompensation in chronic hepatitis C patients with new‐onset diabetes: A nationwide cohort study , 2014, Hepatology.

[7]  P. Nilsson,et al.  Increased risk of cirrhosis and hepatocellular cancer during long-term follow-up of patients with biopsy-proven NAFLD , 2014, Scandinavian journal of gastroenterology.

[8]  L. Marzio,et al.  CEUS and Fibroscan in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. , 2014, World journal of hepatology.

[9]  G. Firneisz Non-alcoholic fatty liver disease and type 2 diabetes mellitus: the liver disease of our age? , 2014, World journal of gastroenterology.

[10]  E. Brunt,et al.  Role of liver biopsy in nonalcoholic fatty liver disease. , 2014, World journal of gastroenterology.

[11]  G. Salles,et al.  Non-alcoholic fatty liver disease and diabetes: from physiopathological interplay to diagnosis and treatment. , 2014, World journal of gastroenterology.

[12]  Mafalda Bourbon,et al.  How good is controlled attenuation parameter and fatty liver index for assessing liver steatosis in general population: correlation with ultrasound , 2014, Liver international : official journal of the International Association for the Study of the Liver.

[13]  M. Rau,et al.  Non-alcoholic fatty liver disease: epidemiology, clinical course, investigation, and treatment. , 2014, Deutsches Arzteblatt international.

[14]  S. Park,et al.  Radiologic evaluation of nonalcoholic fatty liver disease. , 2014, World journal of gastroenterology.

[15]  Yi-Min Zhu,et al.  Diabetes and cancer: Associations, mechanisms, and implications for medical practice. , 2014, World journal of diabetes.

[16]  T. Riley,et al.  Bedside ultrasound in the diagnosis of nonalcoholic fatty liver disease. , 2014, World journal of gastroenterology.

[17]  I. de Sio,et al.  Optimized contrast-enhanced ultrasonography for characterization of focal liver lesions in cirrhosis: A single-center retrospective study , 2014, United European gastroenterology journal.

[18]  Li Ying,et al.  Controlled attenuation parameter for the detection of steatosis severity in chronic liver disease: A meta‐analysis of diagnostic accuracy , 2014, Journal of gastroenterology and hepatology.

[19]  V. de Lédinghen,et al.  Controlled attenuation parameter (CAP) for the diagnosis of steatosis: a prospective study of 5323 examinations. , 2014, Journal of hepatology.

[20]  S. Baik,et al.  Invasive and non-invasive diagnosis of cirrhosis and portal hypertension. , 2014, World journal of gastroenterology.

[21]  Tae Kyoung Kim,et al.  Contrast-enhanced ultrasound in the diagnosis of nodules in liver cirrhosis. , 2014, World journal of gastroenterology.

[22]  S. Azar,et al.  Liver disease and diabetes: association, pathophysiology, and management. , 2014, Diabetes research and clinical practice.

[23]  K. Kowdley,et al.  Controversies in the Diagnosis and Management of NAFLD and NASH. , 2014, Gastroenterology & hepatology.

[24]  Amit G. Singal,et al.  Early Detection, Curative Treatment, and Survival Rates for Hepatocellular Carcinoma Surveillance in Patients with Cirrhosis: A Meta-analysis , 2014, PLoS medicine.

[25]  D. McClain,et al.  Diabetes and Hemochromatosis , 2014, Current Diabetes Reports.

[26]  C. Dietrich,et al.  Challenges for the German Health Care System – Pharmaceuticals , 2014, Endoskopie heute.

[27]  C. Byrne,et al.  Risk of cardiovascular, cardiac and arrhythmic complications in patients with non-alcoholic fatty liver disease. , 2014, World journal of gastroenterology.

[28]  J. Allard,et al.  Clinical approaches to non-alcoholic fatty liver disease. , 2014, World journal of gastroenterology.

[29]  M. Ngu,et al.  Systematic review with meta‐analysis: non‐invasive assessment of non‐alcoholic fatty liver disease – the role of transient elastography and plasma cytokeratin‐18 fragments , 2014, Alimentary pharmacology & therapeutics.

[30]  X. Cui,et al.  Artifacts and Pitfalls in Contrast-Enhanced Ultrasound of the Liver , 2014, Ultraschall in der Medizin.

[31]  Yoshito Itoh,et al.  Limitations of liver biopsy and non-invasive diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. , 2014, World journal of gastroenterology.

[32]  T. Berg,et al.  Non-Invasive Assessment of Hepatic Steatosis in Patients with NAFLD Using Controlled Attenuation Parameter and 1 HMR Spectroscopy , 2014 .

[33]  M. Cole,et al.  Hepatocellular cancer: the impact of obesity, type 2 diabetes and a multidisciplinary team. , 2014, Journal of hepatology.

[34]  R. Ehman,et al.  Liver stiffness is associated with risk of decompensation, liver cancer, and death in patients with chronic liver diseases: a systematic review and meta-analysis. , 2013, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[35]  S. Shin,et al.  Ultrasonographic scoring system score versus liver stiffness measurement in prediction of cirrhosis , 2013, Clinical and molecular hepatology.

[36]  W. Schepp,et al.  Diabetes und Leberzirrhose , 2013, Der Diabetologe.

[37]  Ioan Sporea,et al.  Acoustic radiation force impulse and supersonic shear imaging versus transient elastography for liver fibrosis assessment. , 2013, Ultrasound in medicine & biology.

[38]  A. Diehl,et al.  NAFLD, NASH and liver cancer , 2013, Nature Reviews Gastroenterology &Hepatology.

[39]  M. Friedrich-Rust,et al.  Spectrum and complications of percutaneous ultrasound guided intraabdominal interventions - results of the prospective multicenter DEGUM study , 2013 .

[40]  X. Cui,et al.  Liver elastography, comments on EFSUMB elastography guidelines 2013. , 2013, World journal of gastroenterology.

[41]  E. Bjornsson,et al.  Simple noninvasive systems predict long-term outcomes of patients with nonalcoholic fatty liver disease. , 2013, Gastroenterology.

[42]  S. Verma,et al.  Predictive value of ALT levels for non‐alcoholic steatohepatitis (NASH) and advanced fibrosis in non‐alcoholic fatty liver disease (NAFLD) , 2013, Liver international : official journal of the International Association for the Study of the Liver.

[43]  Ioan Sporea,et al.  Meta‐analysis: ARFI elastography versus transient elastography for the evaluation of liver fibrosis , 2013, Liver international : official journal of the International Association for the Study of the Liver.

[44]  Xin Gao,et al.  Liver Fat Content, Evaluated through Semi-Quantitative Ultrasound Measurement, Is Associated with Impaired Glucose Profiles: A Community-Based Study in Chinese , 2013, PloS one.

[45]  F. Lian,et al.  Contrast-enhanced ultrasonography for the diagnosis of small hepatocellular carcinoma: a meta-analysis and meta-regression analysis , 2013, Tumor Biology.

[46]  G. Labbadia,et al.  Ultrasound evaluation of liver fibrosis: preliminary experience with acoustic structure quantification (ASQ) software , 2013, La radiologia medica.

[47]  G. Tarantino,et al.  Liver-spleen axis: intersection between immunity, infections and metabolism. , 2013, World journal of gastroenterology.

[48]  H. Makhlouf,et al.  Predictors of All-Cause Mortality and Liver-Related Mortality in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD) , 2013, Digestive Diseases and Sciences.

[49]  G. Tarantino,et al.  What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome? , 2013, World journal of gastroenterology.

[50]  D. Schreiber-Dietrich,et al.  Fortuitously discovered liver lesions. , 2013, World journal of gastroenterology.

[51]  S. Bota,et al.  Can transient elastography be a reliable method for assessing liver fibrosis in non alcoholic steatohepatitis (NASH)? , 2013, Medical ultrasonography.

[52]  G. Wong,et al.  Transient elastography: Kill two birds with one stone? , 2013, World journal of hepatology.

[53]  H. Cortez‐Pinto,et al.  Non-invasive diagnosis of non-alcoholic fatty liver disease. A critical appraisal. , 2013, Journal of hepatology.

[54]  W. Rathmann,et al.  Type 2 diabetes: prevalence and relevance of genetic and acquired factors for its prediction. , 2013, Deutsches Arzteblatt international.

[55]  L. Bolondi,et al.  Characterization of Primary and Recurrent Nodules in Liver Cirrhosis Using Contrast-Enhanced Ultrasound: Which Vascular Criteria Should Be Adopted? , 2013, Ultraschall in der Medizin.

[56]  O H Gilja,et al.  EFSUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography.Part 2: Clinical Applications , 2013, Ultraschall in der Medizin.

[57]  M. Friedrich-Rust,et al.  Acoustic radiation force impulse imaging for non‐invasive assessment of liver fibrosis in chronic hepatitis B , 2013, Journal of viral hepatitis.

[58]  F. Schaefer,et al.  EFSUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography. Part 1: Basic Principles and Technology , 2013, Ultraschall in der Medizin.

[59]  P. Malfertheiner,et al.  Clinical Characteristics and Time Trends in Etiology of Hepatocellular Cancer in Germany , 2013, Digestion.

[60]  R. Ramakrishna,et al.  Phenotypic and clinical manifestations of compound heterozygous genetic haemochromatosis (CHGH): a non‐invasive approach to clinical management , 2013, Internal medicine journal.

[61]  Odd Helge Gilja,et al.  Quantitative measurement of ultrasound attenuation and Hepato-Renal Index in Non-Alcoholic Fatty Liver Disease. , 2013, Medical ultrasonography.

[62]  S. E. Park,et al.  Increased risk of type 2 diabetes in subjects with both elevated liver enzymes and ultrasonographically diagnosed nonalcoholic fatty liver disease: a 4-year longitudinal study. , 2013, Archives of medical research.

[63]  S. Twigg,et al.  Diabetes and nonalcoholic Fatty liver disease: a pathogenic duo. , 2013, Endocrine reviews.

[64]  B. Goldberg,et al.  Radiological Clinical Practice Guidelines Published in the Last Decade: A Bibliometric Analysis , 2019, Journal of the Belgian Society of Radiology.

[65]  R. Schiumerini,et al.  Review article: the diagnosis of non‐alcoholic fatty liver disease – availability and accuracy of non‐invasive methods , 2013, Alimentary pharmacology & therapeutics.

[66]  Moshe Leshno,et al.  Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification. , 2013, World journal of gastroenterology.

[67]  H. Cotrim,et al.  Sonographic hepatorenal ratio: A noninvasive method to diagnose nonalcoholic steatosis , 2013, Journal of clinical ultrasound : JCU.

[68]  A. Khorana,et al.  Diabetes Mellitus Is Associated With the Presence of Metastatic Spread at Disease Presentation in Hepatocellular Carcinoma , 2012, Cancer investigation.

[69]  H. El‐Serag,et al.  Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review. , 2012, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[70]  E. Bluth,et al.  Hepatorenal index as an accurate, simple, and effective tool in screening for steatosis. , 2012, AJR. American journal of roentgenology.

[71]  F. Loria,et al.  Contrast-enhanced ultrasound of hepatocellular carcinoma: correlation between enhancement pattern and cellular differentiation on histopathlogy , 2012, Updates in Surgery.

[72]  C. Dietrich,et al.  [Focal liver lesion, incidental finding]. , 2012, Deutsche medizinische Wochenschrift.

[73]  Y. Hiasa,et al.  Real‐time tissue elastography for evaluation of hepatic fibrosis and portal hypertension in nonalcoholic fatty liver diseases , 2012, Hepatology.

[74]  Y. Zheng,et al.  Evaluation of liver fibrosis by investigation of hepatic parenchymal perfusion using contrast‐enhanced ultrasound: An animal study , 2012, Journal of clinical ultrasound : JCU.

[75]  A. Lonardo,et al.  Ultrasonographic fatty liver indicator, a novel score which rules out NASH and is correlated with metabolic parameters in NAFLD , 2012, Liver international : official journal of the International Association for the Study of the Liver.

[76]  F. Han,et al.  Contrast-enhanced ultrasonography of hepatocellular carcinoma: correlation between quantitative parameters and histological grading. , 2012, The British journal of radiology.

[77]  H. Dai,et al.  Risk of development of acute pancreatitis with pre-existing diabetes: a meta-analysis , 2012, European journal of gastroenterology & hepatology.

[78]  Y. Takikawa,et al.  Non-invasive determination of hepatic steatosis by acoustic structure quantification from ultrasound echo amplitude. , 2012, World journal of gastroenterology.

[79]  C. Dietrich,et al.  An EFSUMB Introduction into Dynamic Contrast-Enhanced Ultrasound (DCE-US) for Quantification of Tumour Perfusion , 2012, Ultraschall in der Medizin.

[80]  I. Sporea,et al.  Hepatic Elastography for the Assessment of Liver Fibrosis – Present and Future , 2012, Ultraschall in der Medizin.

[81]  Hui Zhu,et al.  Performance of magnetic resonance elastography and diffusion‐weighted imaging for the staging of hepatic fibrosis: A meta‐analysis , 2012, Hepatology.

[82]  A. Pollett,et al.  Controlled Attenuation Parameter (CAP): a noninvasive method for the detection of hepatic steatosis based on transient elastography , 2012, Liver international : official journal of the International Association for the Study of the Liver.

[83]  X. Cui,et al.  Contrast-Enhanced Ultrasound (CEUS) in the Diagnostic Algorithm of Hepatocellular and Cholangiocellular Carcinoma, Comments on the AASLD Guidelines , 2012, Ultraschall in der Medizin.

[84]  Li Zhang,et al.  Artificial neural network aided non-invasive grading evaluation of hepatic fibrosis by duplex ultrasonography , 2012, BMC Medical Informatics and Decision Making.

[85]  L. Adams,et al.  A prospective evaluation of the role of transient elastography for the detection of hepatic fibrosis in type 2 diabetes without overt liver disease , 2012, Scandinavian journal of gastroenterology.

[86]  C. Dietrich,et al.  Challenges for the German Health Care System , 2012, Zeitschrift für Gastroenterologie.

[87]  H-X Xu,et al.  Discrimination between neoplastic and non-neoplastic lesions in cirrhotic liver using contrast-enhanced ultrasound. , 2012, The British journal of radiology.

[88]  C. Trautwein,et al.  Doppler Ultrasound of Hepatic Blood Flow for Noninvasive Evaluation of Liver Fibrosis Compared with Liver Biopsy and Transient Elastography , 2012, Digestive Diseases and Sciences.

[89]  Giovanni Simonetti,et al.  Liver elasticity in NASH patients evaluated with real-time elastography (RTE). , 2012, Ultrasound in medicine & biology.

[90]  Qiwen Ben,et al.  Increased risk of hepatocellular carcinoma in patients with diabetes mellitus: A systematic review and meta‐analysis of cohort studies , 2012, International journal of cancer.

[91]  M. Friedrich-Rust,et al.  Acoustic radiation force impulse-imaging and transient elastography for non-invasive assessment of liver fibrosis and steatosis in NAFLD. , 2012, European journal of radiology.

[92]  J. Marrero,et al.  Effectiveness of Hepatocellular Carcinoma Surveillance in Patients with Cirrhosis , 2012, Cancer Epidemiology, Biomarkers & Prevention.

[93]  Zhiwen Liu,et al.  Diabetes mellitus and risk of hepatocellular carcinoma: a systematic review and meta‐analysis , 2012, Diabetes/metabolism research and reviews.

[94]  F. Sung,et al.  Risk of Hepatocellular Carcinoma in Diabetic Patients and Risk Reduction Associated With Anti-Diabetic Therapy: A Population-Based Cohort Study , 2012, The American Journal of Gastroenterology.

[95]  Meng-Su Zeng,et al.  Standardized Ultrasound Hepatic/Renal Ratio and Hepatic Attenuation Rate to Quantify Liver Fat Content: An Improvement Method , 2011, Obesity.

[96]  F. Piscaglia,et al.  Ultrasound in portal hypertension--part 2--and EFSUMB recommendations for the performance and reporting of ultrasound examinations in portal hypertension. , 2012, Ultraschall in der Medizin.

[97]  T. Ando,et al.  A case of glycogenic hepatopathy developed in a patient with new-onset fulminant type 1 diabetes: the role of image modalities in diagnosing hepatic glycogen deposition including gradient-dual-echo MRI. , 2012, Endocrine journal.

[98]  H. Garg,et al.  Liver Stiffness Measurements in Patients with Different Stages of Nonalcoholic Fatty Liver Disease: Diagnostic Performance and Clinicopathological Correlation , 2012, Digestive Diseases and Sciences.

[99]  T. Kim,et al.  Does hepatic vein transit time performed with contrast-enhanced ultrasound predict the severity of hepatic fibrosis? , 2011, Ultrasound in medicine & biology.

[100]  C. Dietrich,et al.  Frequency of Tumor Entities among Liver Tumors of Unclear Etiology Initially Detected by Sonography in the Noncirrhotic or Cirrhotic Livers of 1349 Patients , 2011, Ultraschall in der Medizin.

[101]  G. Musso,et al.  Meta-analysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity , 2011, Annals of medicine.

[102]  Eliseo Guallar,et al.  Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: A meta‐analysis , 2011, Hepatology.

[103]  Ned C. Rouze,et al.  Noninvasive evaluation of hepatic fibrosis using acoustic radiation force-based shear stiffness in patients with nonalcoholic fatty liver disease. , 2011, Journal of hepatology.

[104]  F. Joukar,et al.  Comparison of Portal Vein Doppler Indices and Hepatic Vein Doppler Waveform in Patients with Nonalcoholic Fatty Liver Disease with Healthy Control , 2011, Hepatitis monthly.

[105]  A. Baranova,et al.  Systematic review: the epidemiology and natural history of non‐alcoholic fatty liver disease and non‐alcoholic steatohepatitis in adults , 2011, Alimentary pharmacology & therapeutics.

[106]  Jia Fan,et al.  Prognostic role of diabetes mellitus in hepatocellular carcinoma patients after curative treatments: a meta-analysis. , 2011, Hepatobiliary & pancreatic diseases international : HBPD INT.

[107]  M. Manns,et al.  Grading of hypervascular hepatocellular carcinoma using late phase of contrast enhanced sonography - a prospective study. , 2011, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[108]  A. Ignee,et al.  Pitfalls and artefacts using contrast enhanced ultrasound. , 2011, Zeitschrift fur Gastroenterologie.

[109]  I. de Sio,et al.  Which Clinical and Sonographic Parameters May Be Useful to Discriminate NASH from Steatosis? , 2011, Journal of clinical gastroenterology.

[110]  G. Simonetti,et al.  Liver contrast enhanced ultrasound perfusion imaging in the evaluation of chronic hepatitis C fibrosis: preliminary results. , 2011, Ultrasound in medicine & biology.

[111]  V. de Lédinghen,et al.  Controlled attenuation parameter (CAP): a novel VCTE™ guided ultrasonic attenuation measurement for the evaluation of hepatic steatosis: preliminary study and validation in a cohort of patients with chronic liver disease from various causes. , 2010, Ultrasound in medicine & biology.

[112]  O. Yokosuka,et al.  Assessment of hepatic fibrosis by analysis of the dynamic behaviour of microbubbles during contrast ultrasonography , 2010, Liver international : official journal of the International Association for the Study of the Liver.

[113]  E. Bonora,et al.  Prevalence of non-alcoholic fatty liver disease and its association with cardiovascular disease in patients with type 1 diabetes. , 2010, Journal of hepatology.

[114]  S. Fereshtehnejad,et al.  Correlation of hepatic vein Doppler waveform and hepatic artery resistance index with the severity of nonalcoholic fatty liver disease , 2010, Journal of clinical ultrasound : JCU.

[115]  Chris Day,et al.  A position statement on NAFLD/NASH based on the EASL 2009 special conference. , 2010, Journal of hepatology.

[116]  J. Stoker,et al.  The diagnostic accuracy of US, CT, MRI and 1H-MRS for the evaluation of hepatic steatosis compared with liver biopsy: a meta-analysis , 2010, European Radiology.

[117]  W. Jochum,et al.  Glykogen-Hepatopathie bei Diabetes mellitus Typ 1 , 2010 .

[118]  R. Allan,et al.  Accuracy of ultrasound to identify chronic liver disease. , 2010, World journal of gastroenterology.

[119]  Wenping Wang,et al.  Intrahepatic transit time predicts liver fibrosis in patients with chronic hepatitis B: quantitative assessment with contrast-enhanced ultrasonography. , 2010, Ultrasound in medicine & biology.

[120]  Scott Harmsen,et al.  Nonalcoholic Fatty Liver Disease Increases Risk of Death Among Patients With Diabetes: A Community-Based Cohort Study , 2010, The American Journal of Gastroenterology.

[121]  Rocio Lopez,et al.  The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis , 2010, Hepatology.

[122]  G. Wong,et al.  Development of a non‐invasive algorithm with transient elastography (Fibroscan) and serum test formula for advanced liver fibrosis in chronic hepatitis B , 2010, Alimentary pharmacology & therapeutics.

[123]  S. Caldwell,et al.  The Natural History of Non-Alcoholic Fatty Liver Disease , 2010, Digestive Diseases.

[124]  Hirokazu Takahashi,et al.  Measurement of spleen volume is useful for distinguishing between simple steatosis and early‐stage non‐alcoholic steatohepatitis , 2010, Hepatology research : the official journal of the Japan Society of Hepatology.

[125]  D. Charytan,et al.  Cardiovascular Complications in Diabetic Kidney Disease , 2010, Seminars in dialysis.

[126]  S. Delorme,et al.  [Costs of clinical ultrasound examinations - an economical cost calculation and analysis]. , 2010, Ultraschall in der Medizin.

[127]  B. Boehm,et al.  Prevalence and Risk Factors of Focal Sparing in Hepatic Steatosis , 2010, Ultraschall in der Medizin.

[128]  Chia-Yang Hsu,et al.  Diabetes mellitus as an independent prognostic predictor and its association with renal dysfunction in patients with hepatocellular carcinoma , 2010, Liver international : official journal of the International Association for the Study of the Liver.

[129]  A. McCullough,et al.  Validity of real time ultrasound in the diagnosis of hepatic steatosis: a prospective study. , 2009, Journal of hepatology.

[130]  Marco Salvatore,et al.  Sonographic hepatic-renal ratio as indicator of hepatic steatosis: comparison with (1)H magnetic resonance spectroscopy. , 2009, Metabolism: clinical and experimental.

[131]  K. Washington,et al.  Assessment of Hepatic Steatosis by Expert Pathologists: The End of a Gold Standard , 2009, Annals of surgery.

[132]  Hiroyuki Hachiya,et al.  B-mode ultrasound with algorithm based on statistical analysis of signals: evaluation of liver fibrosis in patients with chronic hepatitis C. , 2009, AJR. American journal of roentgenology.

[133]  F. Schick,et al.  Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance. , 2009, Journal of hepatology.

[134]  J. Marrero,et al.  Meta‐analysis: surveillance with ultrasound for early‐stage hepatocellular carcinoma in patients with cirrhosis , 2009, Alimentary pharmacology & therapeutics.

[135]  W. Schepp,et al.  [Hepatogenous diabetes - diagnostics and treatment]. , 2009, Zeitschrift fur Gastroenterologie.

[136]  G. Tarantino,et al.  Could inflammatory markers help diagnose nonalcoholic steatohepatitis? , 2009, European journal of gastroenterology & hepatology.

[137]  Zamir Halpern,et al.  Diagnostic value of a computerized hepatorenal index for sonographic quantification of liver steatosis. , 2009, AJR. American journal of roentgenology.

[138]  P. Couzigou,et al.  Liver fibrosis staging with contrast-enhanced ultrasonography: prospective multicenter study compared with METAVIR scoring , 2009, European Radiology.

[139]  A. Avogaro,et al.  Nonalcoholic fatty liver disease (NAFLD) in nonobese patients with diabetes: Prevalence and relationships with hemodynamic alterations detected with Doppler sonography(). , 2009, Journal of ultrasound.

[140]  L. N. Valenti,et al.  Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes , 2008, Hepatology.

[141]  F. Marra,et al.  Accuracy and reproducibility of transient elastography for the diagnosis of fibrosis in pediatric nonalcoholic steatohepatitis , 2008, Hepatology.

[142]  J. Buckels,et al.  Needle track seeding following biopsy of liver lesions in the diagnosis of hepatocellular cancer: a systematic review and meta-analysis , 2008, Gut.

[143]  I. Sporea,et al.  Why, who and how should perform liver biopsy in chronic liver diseases. , 2008, World journal of gastroenterology.

[144]  M. Kudo,et al.  Diagnostic Accuracy of Imaging for Liver Cirrhosis Compared to Histologically Proven Liver Cirrhosis , 2008, Intervirology.

[145]  C. Schmieder,et al.  [What's the price of routine sonography--results of an analysis of costs and processes in a district hospital]. , 2008, Ultraschall in der Medizin.

[146]  B. Hillner,et al.  A decision analysis study of the value of a liver biopsy in nonalcoholic steatohepatitis , 2008, Liver international : official journal of the International Association for the Study of the Liver.

[147]  Alessandro de Moura Almeida,et al.  Fatty liver disease in severe obese patients: diagnostic value of abdominal ultrasound. , 2008, World journal of gastroenterology.

[148]  A. Schuler,et al.  Klinische Sonographie und sonographische Differenzialdiagnose , 2008 .

[149]  L. Katsnelson,et al.  Interobserver and intraobserver variability in the sonographic assessment of fatty liver. , 2007, AJR. American journal of roentgenology.

[150]  Yuichi Harano,et al.  The Severity of Ultrasonographic Findings in Nonalcoholic Fatty Liver Disease Reflects the Metabolic Syndrome and Visceral Fat Accumulation , 2007, The American Journal of Gastroenterology.

[151]  Jeong Won Lee,et al.  The echotextural characteristics for the diagnosis of the liver cirrhosis using the sonographic images , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[152]  A. Ignee,et al.  Evaluation of hepatic steatosis by ultrasound in patients with chronic hepatitis C virus infection. , 2007, Liver international : official journal of the International Association for the Study of the Liver.

[153]  F. Moriyasu,et al.  Decrease in accumulation of ultrasound contrast microbubbles in non‐alcoholic steatohepatitis , 2007, Hepatology research : the official journal of the Japan Society of Hepatology.

[154]  H-X Xu,et al.  Correlation between enhancement pattern of hepatocellular carcinoma on real-time contrast-enhanced ultrasound and tumour cellular differentiation on histopathology. , 2007, The British journal of radiology.

[155]  T. Therneau,et al.  The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD , 2007, Hepatology.

[156]  Jaw-Town Lin,et al.  Diagnostic Value of Ultrasonographic Examination for Nonalcoholic Steatohepatitis in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery , 2007, Obesity surgery.

[157]  L. Ferrell,et al.  Correlation of paired liver biopsies in morbidly obese patients with suspected nonalcoholic fatty liver disease , 2006, Hepatology.

[158]  R. Torella,et al.  The role of bright liver echo pattern on ultrasound B-mode examination in the diagnosis of liver steatosis. , 2006, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[159]  O. Cummings,et al.  Glycogenic Hepatopathy: An Underrecognized Hepatic Complication of Diabetes Mellitus , 2006, The American journal of surgical pathology.

[160]  Lungen Lu,et al.  Correlation between ultrasonographic and pathologic diagnosis of liver fibrosis due to chronic virus hepatitis. , 2006, World journal of gastroenterology.

[161]  R. Pozzi Mucelli,et al.  Accuracy of ultrasound in the detection of liver fibrosis in chronic viral hepatitis. , 2005, La Radiologia medica.

[162]  P. Giral,et al.  Sampling variability of liver biopsy in nonalcoholic fatty liver disease. , 2005, Gastroenterology.

[163]  H. Sugimoto,et al.  Signal intensity of the liver parenchyma in microbubble contrast agent in the late liver phase reflects advanced fibrosis of the liver , 2005, Liver international : official journal of the International Association for the Study of the Liver.

[164]  A. Ignee,et al.  Sonographic Characterisation of Hepatocellular Carcinoma at Time of Diagnosis , 2005, Zeitschrift fur Gastroenterologie.

[165]  G. Radaelli,et al.  Abdominal ultrasonography in inheredited diseases of carbohydrate metabolism. , 2005, La Radiologia medica.

[166]  Guitao Cao,et al.  Liver Fibrosis Identification Based on Ultrasound Images , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[167]  Jonathan C. Cohen,et al.  Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity , 2004, Hepatology.

[168]  C. Aubé,et al.  New Doppler ultrasound signs improve the non-invasive diagnosis of cirrhosis or severe liver fibrosis , 2004, European journal of gastroenterology & hepatology.

[169]  C. Mottin,et al.  The Role of Ultrasound in the Diagnosis of Hepatic Steatosis in Morbidly Obese Patients , 2004, Obesity surgery.

[170]  M. Pompili,et al.  Hepatocellular carcinomas <2 cm in diameter complicating cirrhosis: ultrasound and clinical features in 153 consecutive patients , 2004, Liver international : official journal of the International Association for the Study of the Liver.

[171]  Yoshito Tsushima,et al.  Spleen Enlargement in Patients with Nonalcoholic Fatty Liver , 2004, Digestive Diseases and Sciences.

[172]  Pai-Chi Li,et al.  Liver fibrosis grade classification with B-mode ultrasound. , 2003, Ultrasound in medicine & biology.

[173]  T. Sauerbruch,et al.  Bleeding complications after percutaneous liver biopsy. An analysis of risk factors. , 2003, Digestion.

[174]  Erick M Remer,et al.  The utility of radiological imaging in nonalcoholic fatty liver disease. , 2002, Gastroenterology.

[175]  G Bodemar,et al.  Increased liver echogenicity at ultrasound examination reflects degree of steatosis but not of fibrosis in asymptomatic patients with mild/moderate abnormalities of liver transaminases. , 2002, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[176]  M. Horowitz,et al.  Prevalence of gastrointestinal symptoms associated with diabetes mellitus: a population-based survey of 15,000 adults. , 2001, Archives of internal medicine.

[177]  P. Bedossa,et al.  Ultrasonographic diagnosis of hepatic fibrosis or cirrhosis. , 1999, Journal of hepatology.

[178]  C. Dietrich,et al.  Hepatic and portal vein flow pattern in correlation with intrahepatic fat deposition and liver histology in patients with chronic hepatitis C. , 1998, AJR. American journal of roentgenology.

[179]  L. Bolondi,et al.  What is the criterion for differentiating chronic hepatitis from compensated cirrhosis? A prospective study comparing ultrasonography and percutaneous liver biopsy. , 1997, Journal of hepatology.

[180]  C. Dietrich,et al.  Sonographic detection of focal changes in the liver hilus in patients receiving corticosteroid therapy. , 1997, Zeitschrift fur Gastroenterologie.

[181]  H. Reinwald [Diagnosis and therapy of hepatocellular carcinoma]. , 1997, Medizinische Klinik.

[182]  C. Dicks-Mireaux,et al.  Hepatic ultrasound findings in the glycogen storage diseases. , 1994, The British journal of radiology.

[183]  L. Solbiati,et al.  240 Hepatocellular Carcinomas: Ultrasound Features, Tumor Size, Cytologic and Histologic Patterns, Serum Alpha-Fetoprotein and HBs Ag , 1987, Tumori.