Autophagy and acetaminophen hepatotoxicity: how useful are Atg7-deficient mice?

[1]  H. Jaeschke,et al.  Activation of autophagy protects against acetaminophen‐induced hepatotoxicity , 2012, Hepatology.

[2]  Hartmut Jaeschke,et al.  Current issues with acetaminophen hepatotoxicity--a clinically relevant model to test the efficacy of natural products. , 2011, Life sciences.

[3]  M. Komatsu,et al.  Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy , 2009, Aging.

[4]  T. Fujimura,et al.  Comprehensive proteomics analysis of autophagy-deficient mouse liver. , 2008, Biochemical and biophysical research communications.

[5]  Masaaki Komatsu,et al.  Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice , 2007, Cell.

[6]  H. Jaeschke,et al.  Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: protection by N-acetyl cysteine. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.

[7]  H. Jaeschke,et al.  Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis? , 2002, Toxicological sciences : an official journal of the Society of Toxicology.

[8]  P. G. Wells,et al.  Biphasic modulation of acetaminophen bioactivation and hepatotoxicity by pretreatment with the interferon inducer polyinosinic-polycytidylic acid. , 1990, Journal of Pharmacology and Experimental Therapeutics.

[9]  井草 祐樹.  Loss of autophagy promotes murine acetaminophen hepatotoxicity , 2011 .

[10]  Hartmut Jaeschke,et al.  Intracellular signaling mechanisms of acetaminophen-induced liver cell death. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.