Critical role for peripherally-derived interleukin-10 in mediating the thermoregulatory manifestations of fever and hypothermia in severe forms of lipopolysaccharide-induced inflammation

[1]  W. Cheadle,et al.  Poor outcome in bacterial peritonitis is associated with dysregulated microRNAs and an increased inflammatory response. , 2013, Surgery.

[2]  A. Hao,et al.  Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia , 2013, Journal of Neuroinflammation.

[3]  H. Qian,et al.  Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells. , 2012, Endocrinology.

[4]  A. Planas,et al.  Induction of COX-2 Enzyme and Down-regulation of COX-1 Expression by Lipopolysaccharide (LPS) Control Prostaglandin E2 Production in Astrocytes* , 2012, The Journal of Biological Chemistry.

[5]  J. Roth,et al.  Differences in the relative involvement of peripherally released interleukin (IL)-6, brain IL-1β and prostanoids in mediating lipopolysaccharide-induced fever and sickness behavior , 2011, Psychoneuroendocrinology.

[6]  J. Roth,et al.  Spatiotemporal nuclear factor interleukin‐6 expression in the rat brain during lipopolysaccharide‐induced fever is linked to sustained hypothalamic inflammatory target gene induction , 2011, The Journal of comparative neurology.

[7]  R. Sabat.  IL-10 family of cytokines. , 2010, Cytokine & growth factor reviews.

[8]  Manuel D. Díaz-Muñoz,et al.  Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages. , 2010, Cellular Signalling.

[9]  J. Pestka,et al.  Induction of suppressors of cytokine signaling by the trichothecene deoxynivalenol in the mouse. , 2009, Toxicological sciences : an official journal of the Society of Toxicology.

[10]  A. A. Romanovsky,et al.  Cyclooxygenase-1 or -2--which one mediates lipopolysaccharide-induced hypothermia? , 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

[11]  Rodney W. Johnson,et al.  Cognitive deficits in interleukin-10-deficient mice after peripheral injection of lipopolysaccharide , 2009, Brain, Behavior, and Immunity.

[12]  S. Poole,et al.  Interleukin (IL)-6 and IL-1β act synergistically within the brain to induce sickness behavior and fever in rats , 2008, Brain, Behavior, and Immunity.

[13]  S. Poole,et al.  Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain. , 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

[14]  J. Roth,et al.  Nuclear STAT3 translocation in guinea pig and rat brain endothelium during systemic challenge with lipopolysaccharide and interleukin‐6 , 2005, The Journal of comparative neurology.

[15]  P. Murray.  The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[16]  C. Blatteis,et al.  Cytokines, PGE2 and endotoxic fever: a re-assessment. , 2005, Prostaglandins & other lipid mediators.

[17]  R. Tisch,et al.  Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity. , 2004, Blood.

[18]  I. Chaudry,et al.  The role of interleukin-10 in the regulation of the systemic inflammatory response following trauma-hemorrhage. , 2004, Biochimica et Biophysica Acta.

[19]  A. A. Romanovsky,et al.  Prostaglandin E2 as a mediator of fever: synthesis and catabolism. , 2004, Frontiers in bioscience : a journal and virtual library.

[20]  Anders Blomqvist,et al.  Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis , 2003, Nature Neuroscience.

[21]  Lei-Chin Chen,et al.  Functional Cooperation of Simian Virus 40 Promoter Factor 1 and CCAAT/Enhancer-Binding Protein β and δ in Lipopolysaccharide-Induced Gene Activation of IL-10 in Mouse Macrophages1 , 2003, The Journal of Immunology.

[22]  C. Ball,et al.  Endogenous Interleukin‐10 is Required for the Defervescence of Fever Evoked by Local Lipopolysaccharide‐Induced and Staphylococcus Aureus‐Induced Inflammation in Rats , 2003, The Journal of physiology.

[23]  A. Yoshimura,et al.  Regulation of cytokine signaling and inflammation. , 2002, Cytokine & growth factor reviews.

[24]  Makoto Murakami,et al.  Prostaglandin E synthase. , 2002, Prostaglandins & other lipid mediators.

[25]  A. Yoshimura,et al.  Involvement of Suppressor of Cytokine Signaling-3 as a Mediator of the Inhibitory Effects of IL-10 on Lipopolysaccharide-Induced Macrophage Activation1 , 2002, The Journal of Immunology.

[26]  J. Bol,et al.  Site-specific modulation of LPS-induced fever and interleukin-1 beta expression in rats by interleukin-10. , 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

[27]  Warren S. Alexander,et al.  Suppressors of cytokine signalling (SOCS) in the immune system , 2002, Nature Reviews Immunology.

[28]  L. Leon.  Invited review: cytokine regulation of fever: studies using gene knockout mice. , 2002, Journal of applied physiology.

[29]  I. Udalova,et al.  Evidence for a Dual Mechanism for IL-10 Suppression of TNF-α Production That Does Not Involve Inhibition of p38 Mitogen-Activated Protein Kinase or NF-κB in Primary Human Macrophages1 , 2002, The Journal of Immunology.

[30]  L. Crofford,et al.  Microsomal Prostaglandin E Synthase Is Regulated by Proinflammatory Cytokines and Glucocorticoids in Primary Rheumatoid Synovial Cells1 , 2001, The Journal of Immunology.

[31]  S. Saccani,et al.  Two Waves of Nuclear Factor κb Recruitment to Target Promoters , 2001, The Journal of experimental medicine.

[32]  D. Berg,et al.  IL-10 Is a Central Regulator of Cyclooxygenase-2 Expression and Prostaglandin Production1 , 2001, The Journal of Immunology.

[33]  D. Riendeau,et al.  Cloning, Expression, and Up-regulation of Inducible Rat Prostaglandin E Synthase during Lipopolysaccharide-induced Pyresis and Adjuvant-induced Arthritis* , 2001, The Journal of Biological Chemistry.

[34]  M. Kluger,et al.  Molecular Mechanisms of Fever and Endogenous Antipyresis , 2000, Annals of the New York Academy of Sciences.

[35]  M. Mayo,et al.  Interleukin-10 Signaling Blocks Inhibitor of κB Kinase Activity and Nuclear Factor κB DNA Binding* , 1999, The Journal of Biological Chemistry.

[36]  A. Yoshimura,et al.  Interleukin-10 (IL-10) selectively enhances CIS3/SOCS3 mRNA expression in human neutrophils: evidence for an IL-10-induced pathway that is independent of STAT protein activation. , 1999, Blood.

[37]  H. Dickensheets,et al.  The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes. , 1999, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

[38]  Y. Wang,et al.  The febrile response to lipopolysaccharide is blocked in cyclooxygenase-2−/−, but not in cyclooxygenase-1−/− mice , 1999, Brain Research.

[39]  H. Dickensheets,et al.  Interleukin-10 Inhibits Expression of Both Interferon – and Interferon γ– Induced Genes by Suppressing Tyrosine Phosphorylation of STAT1 , 1999 .

[40]  C. Ball,et al.  Rat interleukin 6: expression in recombinant Escherichia coli, purification and development of a novel ELISA. , 1999, Cytokine.

[41]  P. Lipsky,et al.  Cyclooxygenase in biology and disease , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[42]  Lisa R Leon,et al.  Role of IL-6 and TNF in thermoregulation and survival during sepsis in mice. , 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

[43]  L. Leon,et al.  Exacerbated febrile responses to LPS, but not turpentine, in TNF double receptor-knockout mice. , 1997, The American journal of physiology.

[44]  William L. Smith,et al.  Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2* , 1996, The Journal of Biological Chemistry.

[45]  T. Evans,et al.  Differential regulation of cyclo-oxygenase-1 and cyclo-oxygenase-2 gene expression by lipopolysaccharide treatment in vivo in the rat. , 1996, Clinical science.

[46]  G. Wong,et al.  TNF soluble receptor and antiserum against TNF enhance lipopolysaccharide fever in mice. , 1995, The American journal of physiology.

[47]  M. Billah,et al.  IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells. , 1994, Journal of immunology.

[48]  S. Akira,et al.  Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[49]  R. Cooper,et al.  Relationships between local inflammation, interleukin‐6 concentration and the acute phase protein response in arthritis patients , 1991, European journal of clinical investigation.

[50]  T. Espevik,et al.  A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. , 1986, Journal of immunological methods.

[51]  S. Iyer,et al.  Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease. , 2012, Critical reviews in immunology.

[52]  J. B. Tatro,et al.  Endogenous antipyretics. , 2000, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[53]  L. Leon,et al.  An antipyretic role for interleukin-10 in LPS fever in mice. , 1999, American journal of physiology. Regulatory, integrative and comparative physiology.

[54]  M. Mayo,et al.  Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. , 1999, The Journal of biological chemistry.

[55]  H. Dickensheets,et al.  Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma- induced genes by suppressing tyrosine phosphorylation of STAT1. , 1999, Blood.

[56]  L. Leon,et al.  Fever and Antipyresis , 1994 .

[57]  L. Leon,et al.  Chapter 22 Fever and antipyresis , 1998 .

[58]  A. Baldwin,et al.  The NF-kappa B and I kappa B proteins: new discoveries and insights. , 1996, Annual review of immunology.

[59]  A. Baldwin,et al.  THE NF-κB AND IκB PROTEINS: New Discoveries and Insights , 1996 .

[60]  P. Lansdorp,et al.  Production of hybridoma growth factor by human monocytes , 1987, European journal of immunology.

[61]  G. Paxinos,et al.  The Rat Brain in Stereotaxic Coordinates , 1983 .