Hepatic Stellate Cells Inhibit T Cells through Active TGF-b1 from a Cell Surface–Bound Latent TGF-b1/GARP Complex

[1]  P. Anderson,et al.  Mesenchymal Stromal Cells Express GARP/LRRC32 on Their Surface: Effects on Their Biology and Immunomodulatory Capacity , 2014, Stem cells.

[2]  E. Shevach,et al.  Release of Active TGF-β1 from the Latent TGF-β1/GARP Complex on T Regulatory Cells Is Mediated by Integrin β8 , 2014, The Journal of Immunology.

[3]  S. Markowitz,et al.  Myeloid-Derived Suppressor Cells as a Potential Therapy for Experimental Autoimmune Myasthenia Gravis , 2014, The Journal of Immunology.

[4]  R. Schwabe,et al.  Fate-tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its etiology , 2013, Nature Communications.

[5]  B. Sangro,et al.  Trial of complete weaning from immunosuppression for liver transplant recipients: Factors predictive of tolerance , 2013, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[6]  J. Fung,et al.  Human Hepatic Stellate Cells Inhibit T-Cell Response Through B7-H1 Pathway , 2013, Transplantation.

[7]  E. Shevach,et al.  Regulation of the Expression of GARP/Latent TGF-β1 Complexes on Mouse T Cells and Their Role in Regulatory T Cell and Th17 Differentiation , 2013, The Journal of Immunology.

[8]  T. Springer,et al.  GARP regulates the bioavailability and activation of TGFβ , 2012, Molecular biology of the cell.

[9]  J. Fung,et al.  Hepatic stellate cells regulate immune response by way of induction of myeloid suppressor cells in mice , 2011, Hepatology.

[10]  A. Dhawan,et al.  Human hepatocyte transplantation: current experience and future challenges , 2010, Nature Reviews Gastroenterology &Hepatology.

[11]  P. Coulie,et al.  Membrane protein GARP is a receptor for latent TGF‐β on the surface of activated human Treg , 2009, European journal of immunology.

[12]  E. Shevach,et al.  GARP (LRRC32) is essential for the surface expression of latent TGF-β on platelets and activated FOXP3+ regulatory T cells , 2009, Proceedings of the National Academy of Sciences.

[13]  D. Unutmaz,et al.  Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells , 2009, Proceedings of the National Academy of Sciences.

[14]  S. Dooley,et al.  IFN-γ abrogates profibrogenic TGF-β signaling in liver by targeting expression of inhibitory and receptor Smads , 2007 .

[15]  B. John,et al.  Cellular and molecular mechanisms of liver tolerance , 2006, Immunological reviews.

[16]  C. Gandhi,et al.  Inhibition of T‐cell responses by hepatic stellate cells via B7‐H1–mediated T‐cell apoptosis in mice , 2004, Hepatology.

[17]  S. Qian,et al.  Liver stellate cells suppress dendritic cells through IL-10. , 2004, Transplantation proceedings.

[18]  G. Zhu,et al.  B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes. , 2004, Immunity.

[19]  Justin P. Annes,et al.  Making sense of latent TGFβ activation , 2003, Journal of Cell Science.

[20]  A. Reith,et al.  SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. , 2002, Molecular pharmacology.

[21]  Katsunori Yoshida,et al.  Differential regulation of TGF‐β signal in hepatic stellate cells between acute and chronic rat liver injury , 2002, Hepatology.

[22]  K. Dittmann,et al.  Irradiated homozygous TGF- β 1 knockout fibroblasts show enhanced clonogenic survival as compared with TGF- β 1 wild-type fibroblasts , 2002, International journal of radiation biology.

[23]  D. Brenner,et al.  Hepatic Stellate Cells as a Target for the Treatment of Liver Fibrosis , 2001, Seminars in liver disease.

[24]  C. Orosz,et al.  Unusual patterns of alloimmunity evoked by allogeneic liver parenchymal cells , 2000, Immunological reviews.

[25]  C. H. Conrad,et al.  Myocardial Fibrosis in Transforming Growth Factor β1Heterozygous Mice , 2000 .

[26]  J. Graff,et al.  Smad3 Mutant Mice Develop Metastatic Colorectal Cancer , 1998, Cell.

[27]  B. Portmann,et al.  Defining the outcome of immunosuppression withdrawal after liver transplantation , 1998, Hepatology.

[28]  T. Starzl,et al.  Weaning of immunosuppression in liver transplant recipients. , 1997, Transplantation.

[29]  D M Bissell,et al.  Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation. , 1995, The Journal of clinical investigation.

[30]  T. Starzl,et al.  Murine liver allograft transplantation: Tolerance and donor cell chimerism , 1994, Hepatology.

[31]  M. Sporn,et al.  Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[32]  S. Friedman.  Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. , 2008, Physiological reviews.

[33]  P. Bioulac-Sage,et al.  [Mechanisms of hepatic fibrogenesis]. , 2002, Archives de pediatrie : organe officiel de la Societe francaise de pediatrie.

[34]  高槻 光寿.  Weaning of immunosuppression in living donor liver transplant recipients , 2002 .

[35]  J. Massagué,et al.  Controlling TGF- b signaling , 2000 .

[36]  S. Ebner,et al.  Increased levels of surgical adhesions in TGFbeta1 heterozygous mice. , 1999, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

[37]  A. Jezequel,et al.  The Lipocytes in Normal Human Liver , 1981 .

[38]  A. Jezequel,et al.  The lipocytes in normal human liver. A quantitative study. , 1981, Digestion.