DNA damage and mutation: contributors to the age-related alterations in T cell-mediated immune responses?
暂无分享,去创建一个
[1] L. Breimer. Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: The role of dna base damage , 2006, Molecular carcinogenesis.
[2] E. S. Gillespie,et al. In vivo antioxidant status, DNA damage, mutation and DNA repair capacity in cultured lymphocytes from healthy 75- to 80-year-old humans. , 1997, Mutation research.
[3] G. Pawelec,et al. The T cell in the ageing individual 1 This article is based on a presentation to the First International Conference on Aging and Immunology, Bethesda, MD, 16–19 June, 1996. 1 , 1997, Mechanisms of Ageing and Development.
[4] L. Rink,et al. Dysregulation between TH1 and TH2 T cell subpopulations in the elderly , 1996, Mechanisms of Ageing and Development.
[5] A. Fornace,et al. Mammalian DNA damage-inducible genes associated with growth arrest and apoptosis. , 1996, Mutation research.
[6] R. Effros. Insights on immunological aging derived from the T lymphocyte cellular senescence model , 1996, Experimental Gerontology.
[7] R. Paules,et al. DNA damage and cell cycle checkpoints , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[8] Y. Barnett,et al. An investigation of antioxidant status, DNA repair capacity and mutation as a function of age in humans. , 1995, Mutation research.
[9] A. McLean,et al. In vivo estimates of division and death rates of human T lymphocytes. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[10] L. Hartwell,et al. Cell cycle control and cancer. , 1994, Science.
[11] R. Effros,et al. Decline in CD28+ T cells in centenarians and in long-term T cell cultures: A possible cause for both in vivo and in vitro immunosenescence , 1994, Experimental Gerontology.
[12] E. S. Gillespie,et al. An investigation of mutation as a function of age in humans. , 1994, Mutation research.
[13] B. Ames,et al. Oxidants, antioxidants, and the degenerative diseases of aging. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[14] T. Lindahl. Instability and decay of the primary structure of DNA , 1993, Nature.
[15] R. Simmons,et al. Reactive nitrogen intermediates suppress the primary immunologic response to Listeria. , 1993, Journal of immunology.
[16] K. Kinzler,et al. The multistep nature of cancer. , 1993, Trends in genetics : TIG.
[17] D. Longo,et al. Overexpression of mitochondrial manganese superoxide dismutase promotes the survival of tumor cells exposed to interleukin‐1, tumor necrosis factor, selected anticancer drugs, and ionizing radiation , 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[18] Bunker Vw. Free radicals, antioxidants and ageing. , 1992 .
[19] A. McLean,et al. Lifespan of human lymphocyte subsets defined by CD45 isoforms , 1992, Nature.
[20] C B Harley,et al. Telomere length predicts replicative capacity of human fibroblasts. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[21] C. Franceschi,et al. Genomic Instability and Aging , 1992 .
[22] A. Zwinderman,et al. Use of the clonal assay for the measurement of frequencies of HPRT mutants in T-lymphocytes from five control populations. , 1991, Mutation research.
[23] C. Franceschi,et al. Aging, Longevity, and Cancer: Studies in Down's Syndrome and Centenarians a , 1991, Annals of the New York Academy of Sciences.
[24] Veikko Hayatsu. Mutagens in Food Detection and Prevention , 1991 .
[25] W. Dröge,et al. Interleukin-2 mRNA expression, lymphokine production and DNA synthesis in glutathione-depleted T cells. , 1990, Cellular immunology.
[26] C. Harley,et al. Telomeres shorten during ageing of human fibroblasts , 1990, Nature.
[27] D. Goeddel,et al. Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism , 1988, Science.
[28] E. Mullaart,et al. Age-dependent accumulation of alkali-labile sites in DNA of post-mitotic but not in that of mitotic rat liver cells , 1988, Mechanisms of Ageing and Development.
[29] M. Green,et al. A further assessment of factors influencing measurements of thioguanine-resistant mutant frequency in circulating T-lymphocytes. , 1988, Mutation research.
[30] Y. Nakatsuru,et al. Carcinogenic effect of the simultaneous administration of five heterocyclic amines to F344 rats. , 1987, Japanese journal of cancer research : Gann.
[31] T. Makinodan,et al. Frequency of 6-thioguanine-resistant T cells is inversely related to the declining T-cell activities in aging mice. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[32] Kevin J. Trainor,et al. Mutation frequency in human lymphocytes increases with age , 1984, Mechanisms of Ageing and Development.
[33] A. Morley,et al. Human lymphocytes resistant to 6-thioguanine increase with age , 1982, Mechanisms of Ageing and Development.
[34] J. Oppenheim,et al. Macrophage-mediated suppression. I. Evidence for participation of both hdyrogen peroxide and prostaglandins in suppression of murine lymphocyte proliferation. , 1980, Journal of immunology.
[35] L. Hayflick,et al. The serial cultivation of human diploid cell strains. , 1961, Experimental cell research.
[36] B. Lambert,et al. Reduced proliferation rate of hypoxanthine‐phosphoribosyl transferase mutant human T‐lymphocytes in vitro , 1996, Environmental and molecular mutagenesis.
[37] C. Franceschi,et al. The immunology of exceptional individuals: the lesson of centenarians. , 1995, Immunology today.
[38] T. Buttke,et al. Oxidative stress as a mediator of apoptosis. , 1994, Immunology today.
[39] I Hannet,et al. Developmental and maturational changes in human blood lymphocyte subpopulations. , 1992, Immunology today.
[40] R. Tice,et al. Basal DNA damage in individual human lymphocytes with age. , 1991, Mutation research.
[41] D. Beare,et al. Hprt mutant frequencies in circulating lymphocytes: population studies using normal donors, exposed groups and cancer-prone syndromes. , 1991, Progress in clinical and biological research.
[42] K. Davies,et al. Protein, lipid and DNA repair systems in oxidative stress: the free-radical theory of aging revisited. , 1991, Gerontology.
[43] T. Sugimura,et al. Successful use of short-term tests for academic purposes: their use in identification of new environmental carcinogens with possible risk for humans. , 1988, Mutation research.
[44] N. Berger. Poly(ADP-ribose) in the cellular response to DNA damage. , 1985, Radiation research.
[45] M. Fenech,et al. The effect of donor age on spontaneous and induced micronuclei. , 1985, Mutation research.
[46] Vijayalaxmi,et al. Measurement of spontaneous and X-irradiation-induced 6-thioguanine-resistant human blood lymphocytes using a T-cell cloning technique. , 1984, Mutation research.
[47] P. Lipsky,et al. Immunosuppression by D-penicillamine in vitro. Inhibition of human T lymphocyte proliferation by copper- or ceruloplasmin-dependent generation of hydrogen peroxide and protection by monocytes. , 1984, The Journal of clinical investigation.