Repeat length variations in polyglutamine disease-associated genes affect body mass index

[1]  M. Gymrek,et al.  A reference haplotype panel for genome-wide imputation of short tandem repeats , 2018, bioRxiv.

[2]  M. Spetter,et al.  Cognitive Control of Eating: the Role of Memory in Appetite and Weight Gain , 2018, Current Obesity Reports.

[3]  A. Hannan,et al.  Tandem repeats mediating genetic plasticity in health and disease , 2018, Nature Reviews Genetics.

[4]  B. Penninx,et al.  Eating styles in major depressive disorder: Results from a large-scale study. , 2018, Journal of psychiatric research.

[5]  Jennifer L. Derenne,et al.  Body Image, Media, and Eating Disorders—a 10-Year Update , 2018, Academic Psychiatry.

[6]  Robert A. Schoevers,et al.  Huntingtin gene repeat size variations affect risk of lifetime depression , 2017, Translational Psychiatry.

[7]  R. Noordam,et al.  Genetic variation in the obesity gene FTO is not associated with decreased fat oxidation: the NEO study , 2017, International Journal of Obesity.

[8]  A. Srivastava,et al.  A Complete Association of an intronic SNP rs6798742 with Origin of Spinocerebellar Ataxia Type 7‐CAG Expansion Loci in the Indian and Mexican Population , 2017, Annals of human genetics.

[9]  A. Beekman,et al.  Large normal-range TBP and ATXN7 CAG repeat lengths are associated with increased lifetime risk of depression , 2017, Translational psychiatry.

[10]  S. Carmo-Silva,et al.  Unraveling the Role of Ataxin-2 in Metabolism , 2017, Trends in Endocrinology & Metabolism.

[11]  D. Rubinsztein,et al.  Polyglutamine tracts regulate beclin 1-dependent autophagy , 2017, Nature.

[12]  J. Zaremba,et al.  High relative frequency of SCA1 in Poland reflecting a potential founder effect , 2016, Neurological Sciences.

[13]  J. McBride,et al.  Gene suppression strategies for dominantly inherited neurodegenerative diseases: lessons from Huntington's disease and spinocerebellar ataxia. , 2016, Human molecular genetics.

[14]  P. Holmans,et al.  DNA repair pathways underlie a common genetic mechanism modulating onset in polyglutamine diseases , 2016, Annals of neurology.

[15]  N. Kolchanov,et al.  Obesity-related known and candidate SNP markers can significantly change affinity of TATA-binding protein for human gene promoters , 2015, BMC Genomics.

[16]  Ross M. Fraser,et al.  Genetic studies of body mass index yield new insights for obesity biology , 2015, Nature.

[17]  S. Pulst,et al.  Modulation of the age at onset in spinocerebellar ataxia by CAG tracts in various genes. , 2014, Brain : a journal of neurology.

[18]  H. Harn,et al.  Polyglutamine (PolyQ) Diseases: Genetics to Treatments , 2014, Cell transplantation.

[19]  A. Jansen,et al.  Large-scale analysis of tandem repeat variability in the human genome , 2014, Nucleic acids research.

[20]  M. Endres,et al.  Increased Catabolic State in Spinocerebellar Ataxia Type 1 Patients , 2014, The Cerebellum.

[21]  L. Velázquez-Pérez,et al.  Origin of the Spinocerebellar Ataxia Type 7 Gene Mutation in Mexican Population , 2013, The Cerebellum.

[22]  J. Jankovic,et al.  Characterization of the Huntington intermediate CAG repeat expansion phenotype in PHAROS , 2013, Neurology.

[23]  Margreet Kloppenburg,et al.  The Netherlands Epidemiology of Obesity (NEO) study: study design and data collection , 2013, European Journal of Epidemiology.

[24]  Shinichi Nakagawa,et al.  A general and simple method for obtaining R2 from generalized linear mixed‐effects models , 2013 .

[25]  G. Ruxton,et al.  Review of alternative approaches to calculation of a confidence interval for the odds ratio of a 2 × 2 contingency table , 2013 .

[26]  M. Saraiva-Pereira,et al.  Body Mass Index is Inversely Correlated with the Expanded CAG Repeat Length in SCA3/MJD Patients , 2012, The Cerebellum.

[27]  N. Sattar,et al.  Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy , 2012, PloS one.

[28]  W. Chung.  An overview of mongenic and syndromic obesities in humans , 2012, Pediatric blood & cancer.

[29]  D. Souza,et al.  Serum insulin‐like system alterations in patients with spinocerebellar ataxia type 3 , 2011, Movement disorders : official journal of the Movement Disorder Society.

[30]  A. Hannan.  TRPing up the genome: Tandem repeat polymorphisms as dynamic sources of genetic variability in health and disease. , 2010, Discovery medicine.

[31]  J. Kaufman,et al.  Testosterone, androgen receptor gene CAG repeat length, mood and behaviour in adolescent males. , 2010, European journal of endocrinology.

[32]  Teri A Manolio,et al.  Genomewide association studies and assessment of the risk of disease. , 2010, The New England journal of medicine.

[33]  Theo Stijnen,et al.  Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. , 2010, Archives of general psychiatry.

[34]  A. Hannan.  Tandem repeat polymorphisms: modulators of disease susceptibility and candidates for 'missing heritability'. , 2010, Trends in genetics : TIG.

[35]  S. Bandinelli,et al.  Interleukin-1 Receptor Antagonist and Incident Depressive Symptoms Over 6 Years in Older Persons: The InCHIANTI Study , 2009, Biological Psychiatry.

[36]  L. Baliko,et al.  Spinocerebellar Ataxia Types 1, 2, 3 and 6: the Clinical Spectrum of Ataxia and Morphometric Brainstem and Cerebellar Findings , 2008, The Cerebellum.

[37]  B. Bloem,et al.  Weight loss in neurodegenerative disorders , 2008, Journal of Neurology.

[38]  Subhajyoti De,et al.  Common variants near MC4R are associated with fat mass, weight and risk of obesity , 2008, Nature Genetics.

[39]  J. Huber.  Diabetes, cognitive function, and the blood-brain barrier. , 2008, Current pharmaceutical design.

[40]  Georg Auburger,et al.  Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice. , 2008, Human molecular genetics.

[41]  Wei-Jei Lee,et al.  Improvement of Insulin Resistance After Obesity Surgery: A Comparison of Gastric Banding and Bypass Procedures , 2008, Obesity surgery.

[42]  A. Beekman,et al.  Inflammatory markers in late-life depression: results from a population-based study. , 2008, Journal of affective disorders.

[43]  P. Chinnery,et al.  Pathogenic expansions of the SCA6 locus are associated with a common CACNA1A haplotype across the globe: founder effect or predisposing chromosome? , 2008, European Journal of Human Genetics.

[44]  S. Reis,et al.  Depression, inflammation, and incident cardiovascular disease in women with suspected coronary ischemia: the National Heart, Lung, and Blood Institute-sponsored WISE study. , 2007, Journal of the American College of Cardiology.

[45]  L. Sharp,et al.  Total testosterone, androgen receptor polymorphism, and depressive symptoms in young black and white men: The CARDIA Male Hormone Study , 2007, Psychoneuroendocrinology.

[46]  W. Melvin,et al.  Gastric Bypass Surgery is Associated with Reduced Inflammation and Less Depression: a Preliminary Investigation , 2007, Obesity surgery.

[47]  Senthil Kumaran,et al.  Measurement of Brain Metabolites in Patients with type 2 Diabetes and Major Depression Using Proton Magnetic Resonance Spectroscopy , 2007, Neuropsychopharmacology.

[48]  M. Jarvelin,et al.  A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity , 2007, Science.

[49]  Edgar Erdfelder,et al.  G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences , 2007, Behavior research methods.

[50]  Laura Herrero,et al.  Obesity, inflammation, and insulin resistance. , 2007, Gastroenterology.

[51]  M. Zitzmann.  Mechanisms of Disease: pharmacogenetics of testosterone therapy in hypogonadal men , 2007, Nature Clinical Practice Urology.

[52]  A. Goldfine,et al.  Inflammation and insulin resistance. , 2006, The Journal of clinical investigation.

[53]  Y. Kashi,et al.  Simple sequence repeats as advantageous mutators in evolution. , 2006, Trends in genetics : TIG.

[54]  Tim-Rasmus Kiehl,et al.  Generation and characterization of Sca2 (ataxin-2) knockout mice. , 2006, Biochemical and biophysical research communications.

[55]  A. Srivastava,et al.  Insights into the mutational history and prevalence of SCA1 in the Indian population through anchored polymorphisms , 2005, Human Genetics.

[56]  D. Cramer,et al.  Androgen receptor cytosine, adenine, guanine repeats, and haplotypes in relation to ovarian cancer risk. , 2005, Cancer research.

[57]  P. Macfarlane,et al.  Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial , 2002, The Lancet.

[58]  A. Schatzberg,et al.  Cortisol activity and cognitive changes in psychotic major depression. , 2001, The American journal of psychiatry.

[59]  B. Walker.  Activation of the hypothalamic-pituitary-adrenal axis in obesity: cause or consequence? , 2001, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[60]  Florian Holsboer,et al.  The Corticosteroid Receptor Hypothesis of Depression , 2000, Neuropsychopharmacology.

[61]  R. Pasquali,et al.  Activity of the hypothalamic–pituitary–adrenal axis in different obesity phenotypes , 2000, International Journal of Obesity.

[62]  S. Pulst,et al.  A novel protein with RNA-binding motifs interacts with ataxin-2. , 2000, Human molecular genetics.

[63]  C. Bouchard,et al.  Familial aggregation of obesity, candidate genes and quantitative trait loci. , 1997, Current opinion in lipidology.

[64]  M. Goran.  Genetic Influences on Human Energy Expenditure and Substrate Utilization , 1997, Behavior genetics.

[65]  M. Höfler,et al.  Pain associated with specific anxiety and depressive disorders in a nationally representative population sample , 2009, Social Psychiatry and Psychiatric Epidemiology.

[66]  K. Ball,et al.  Association between weight perception and psychological distress , 2008, International Journal of Obesity.

[67]  L. Tora,et al.  Both normal and polyglutamine- expanded ataxin-7 are components of TFTC-type GCN5 histone acetyltransferase- containing complexes. , 2006, Biochemical Society symposium.

[68]  D. Gustafson,et al.  Androgen receptor gene repeats and indices of obesity in older adults , 2003, International Journal of Obesity.

[69]  A. von Eckardstein,et al.  The CAG repeat polymorphism in the androgen receptor gene modulates body fat mass and serum concentrations of leptin and insulin in men , 2002, Diabetologia.

[70]  Who Consultation on Obesity.  Obesity: preventing and managing the global epidemic. Report of a WHO consultation. , 2000, World Health Organization technical report series.

[71]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .