How does blood glucose control with insulin save lives in intensive care
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[1] A. Marette,et al. Regulation of expression of glucose transporters by glucose: a review of studies in vivo and in cell cultures , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[2] H. Harris,et al. Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice. , 1990, The Journal of clinical investigation.
[3] M. Fink. Clinical tests of gastrointestinal permeability that rely on the urinary recovery of enterally administered probes can yield invalid results in critically ill patients , 2002, Intensive Care Medicine.
[4] S. Zakynthinos,et al. Activation of the fibrinolytic system and utilization of the coagulation inhibitors in sepsis: comparison with severe sepsis and septic shock , 2001, Intensive Care Medicine.
[5] A. Aljada,et al. Insulin Inhibits Intranuclear Nuclear Factor κB and Stimulates IκB in Mononuclear Cells in Obese Subjects: Evidence for an Anti-inflammatory Effect? , 2001 .
[6] M. Quon,et al. Insulin-stimulated Activation of eNOS Is Independent of Ca2+ but Requires Phosphorylation by Akt at Ser1179 * , 2001, The Journal of Biological Chemistry.
[7] S. Wong,et al. Disturbances in the composition of plasma lipoproteins during gram-negative sepsis in the rat. , 1992, Biochimica et biophysica acta.
[8] R. Vettor,et al. Contact phase of blood coagulation in diabetes mellitus , 1982, European journal of clinical investigation.
[9] B A Mizock,et al. Alterations in fuel metabolism in critical illness: hyperglycaemia. , 2001, Best practice & research. Clinical endocrinology & metabolism.
[10] P. Gaffney,et al. Diabetes mellitus as a hypercoagulable state: its relationship with fibrin fragments and vascular damage. , 1987, Thrombosis research.
[11] R. Grimble. Inflammatory status and insulin resistance , 2002, Current opinion in clinical nutrition and metabolic care.
[12] A. K. Jonassen,et al. Glucose-Insulin-Potassium Reduces Infarct Size When Administered During Reperfusion , 2000, Cardiovascular Drugs and Therapy.
[13] G. Keusch,et al. Infection and diabetes: the case for glucose control. , 1982, The American journal of medicine.
[14] R. Krauss,et al. The hypertriglyceridemia of acquired immunodeficiency syndrome is associated with an increased prevalence of low density lipoprotein subclass pattern B. , 1993, The Journal of clinical endocrinology and metabolism.
[15] E. Ivers,et al. Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock , 2001 .
[16] A. Malhotra,et al. Stress-induced hyperglycemia. , 2001, Critical care clinics.
[17] M. Matthay,et al. Hypoxia regulates gene expression of alveolar epithelial transport proteins. , 2000, Journal of applied physiology.
[18] M. Carr. Diabetes mellitus: a hypercoagulable state. , 2001, Journal of diabetes and its complications.
[19] P. Watson,et al. Hyperinsulinemia enhances transcriptional activity of nuclear factor-kappaB induced by angiotensin II, hyperglycemia, and advanced glycosylation end products in vascular smooth muscle cells. , 2000, Circulation research.
[20] H. Lassen.. A preliminary report on the 1952 epidemic of poliomyelitis in Copenhagen with special reference to the treatment of acute respiratory insufficiency. , 1953, Lancet.
[21] R. Wolfe,et al. Glucose metabolism in man: responses to intravenous glucose infusion. , 1979, Metabolism: clinical and experimental.
[22] Y. Carpentier,et al. Changes in the concentration and composition of plasma lipoproteins during the acute phase response , 2002, Current opinion in clinical nutrition and metabolic care.
[23] D. Sodi-Pallares,et al. Effects of an intravenous infusion of a potassium-glucose-insulin solution on the electrocardiographic signs of myocardial infarction. A preliminary clinical report. , 1962, The American journal of cardiology.
[24] James Stephen Krinsley,et al. Effect of an intensive glucose management protocol on the mortality of critically ill adult patients. , 2004, Mayo Clinic proceedings.
[25] Rüdiger Klein,et al. Role of Brain Insulin Receptor in Control of Body Weight and Reproduction , 2000 .
[26] M. Fink. Cytopathic hypoxia. Mitochondrial dysfunction as mechanism contributing to organ dysfunction in sepsis. , 2001, Critical care clinics.
[27] J H Warner,et al. Science in Medicine , 1985, Osiris.
[28] M. White,et al. Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats. , 1999, The Journal of clinical investigation.
[29] J. Callés-Escandon,et al. Type 2 diabetes: one disease, multiple cardiovascular risk factors. , 1999, Coronary artery disease.
[30] Claude Bernard,et al. Leçons sur les phénomènes de la vie communs aux animaux et aux végétaux , 1878 .
[31] M. Lotz,et al. Cytokine Regulation of Facilitated Glucose Transport in Human Articular Chondrocytes1 , 2001, The Journal of Immunology.
[32] L. Opie. The glucose hypothesis: Relation to acute myocardial ischaemia , 1970 .
[33] G. Grunkemeier,et al. Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures. , 1999, The Annals of thoracic surgery.
[34] Miet Schetz,et al. Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control* , 2003, Critical care medicine.
[35] P. Kwiterovich. Lipoprotein heterogeneity: diagnostic and therapeutic implications. , 2002, The American journal of cardiology.
[36] G. Van den Berghe,et al. Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels. , 2003, The Journal of clinical endocrinology and metabolism.
[37] D. Yellon,et al. Myocardial Protection by Insulin at Reperfusion Requires Early Administration and Is Mediated via Akt and p70s6 Kinase Cell-Survival Signaling , 2001, Circulation research.
[38] John Land,et al. Association between mitochondrial dysfunction and severity and outcome of septic shock , 2002, The Lancet.
[39] Nielson Cp,et al. Inhibition of Polymorphonuclear Leukocyte Respiratory Burst by Elevated Glucose Concentrations in Vitro , 1989 .
[40] G. Van den Berghe,et al. Regulation of insulin-like growth factor binding protein-1 during protracted critical illness. , 2002, The Journal of clinical endocrinology and metabolism.
[41] T. Zimmers,et al. Suppressor of Cytokine Signaling-3 (SOCS-3), a Potential Mediator of Interleukin-6-dependent Insulin Resistance in Hepatocytes* , 2003, The Journal of Biological Chemistry.
[42] M. Quon,et al. Inhibition of Phosphatidylinositol 3-Kinase Enhances Mitogenic Actions of Insulin in Endothelial Cells* , 2002, The Journal of Biological Chemistry.
[43] F Bruyninckx,et al. Insulin therapy protects the central and peripheral nervous system of intensive care patients , 2005, Neurology.
[44] G. Van den Berghe,et al. Reactivation of pituitary hormone release and metabolic improvement by infusion of growth hormone-releasing peptide and thyrotropin-releasing hormone in patients with protracted critical illness. , 1999, The Journal of clinical endocrinology and metabolism.
[45] B A Mizock,et al. Alterations in carbohydrate metabolism during stress: a review of the literature. , 1995, The American journal of medicine.
[46] G. Van den Berghe,et al. A novel in vivo rabbit model of hypercatabolic critical illness reveals a biphasic neuroendocrine stress response. , 2002, Endocrinology.
[47] M. Brownlee. Biochemistry and molecular cell biology of diabetic complications , 2001, Nature.
[48] J. Ward,et al. Electron microscopical studies of vessels in diabetic peripheral neuropathy. , 1980, Journal of clinical pathology.
[49] O. McGuinness,et al. Infection impairs insulin-dependent hepatic glucose uptake during total parenteral nutrition. , 2003, American journal of physiology. Endocrinology and metabolism.
[50] M. Singer,et al. Mitochondrial Dysfunction in Sepsis. , 1999, Current infectious disease reports.
[51] H. Harris,et al. Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death. , 1993, The Journal of clinical investigation.
[52] J. Medina,et al. Endothelin‐1 stimulates the translocation and upregulation of both glucose transporter and hexokinase in astrocytes: relationship with gap junctional communication , 2004, Journal of neurochemistry.
[53] D. Powell,et al. Identification of an insulin-responsive element in the promoter of the human gene for insulin-like growth factor binding protein-1. , 1993, The Journal of biological chemistry.
[54] R. Wolfe,et al. Glucose metabolism in severely burned patients. , 1979, Metabolism: clinical and experimental.
[55] A. Sumner,et al. The physiology of lipoproteins , 2002, Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
[56] G. Van den Berghe,et al. A paradoxical gender dissociation within the growth hormone/insulin-like growth factor I axis during protracted critical illness. , 2000, The Journal of clinical endocrinology and metabolism.
[57] J. Rask-Madsen,et al. High glucose impairs superoxide production from isolated blood neutrophils , 2003, Intensive Care Medicine.
[58] D. Accili,et al. Effects of insulin on prenylation as a mechanism of potentially detrimental influence of hyperinsulinemia. , 2000, Endocrinology.
[59] M. Taskinen. Pathogenesis of dyslipidemia in type 2 diabetes. , 2001, Experimental and clinical endocrinology & diabetes.
[60] A. Marette. Mediators of cytokine-induced insulin resistance in obesity and other inflammatory settings , 2002, Current opinion in clinical nutrition and metabolic care.
[61] G. Schernthaner,et al. Decreased Protein C Levels in Patients With Insulin-Dependent Type I Diabetes Mellitus , 1986, Diabetes.
[62] G. Van den Berghe,et al. Metabolic, endocrine, and immune effects of stress hyperglycemia in a rabbit model of prolonged critical illness. , 2003, Endocrinology.
[63] W. Mccumbee,et al. Regulation of glucose transport by angiotensin II and glucose in cultured vascular smooth muscle cells , 1998, Journal of cellular physiology.
[64] A. Vincent,et al. Oxidative Stress and Programmed Cell Death in Diabetic Neuropathy , 2002, Annals of the New York Academy of Sciences.
[65] R. Wolfe,et al. Effect of severe burn injury on substrate cycling by glucose and fatty acids. , 1987, The New England journal of medicine.
[66] P. Pozzilli,et al. Infections and Diabetes: Mechanisms and Prospects for Prevention , 1994, Diabetic medicine : a journal of the British Diabetic Association.
[67] B. Mcverry,et al. Diabetes, a hypercoagulable state? Hemostatic variables in newly diagnosed type 2 diabetic patients. , 1983, Acta haematologica.
[68] Timothy W. Evans,et al. Glucose Control and Mortality in Critically Ill Patients , 2003 .
[69] M Schetz,et al. Intensive insulin therapy in critically ill patients. , 2001, The New England journal of medicine.
[70] M. White,et al. SOCS-1 and SOCS-3 Block Insulin Signaling by Ubiquitin-mediated Degradation of IRS1 and IRS2* , 2002, The Journal of Biological Chemistry.
[71] P. Barie,et al. Low lipid concentrations in critical illness: implications for preventing and treating endotoxemia. , 1996, Critical care medicine.
[72] G. Van den Berghe,et al. Regulation of the somatotropic axis by intensive insulin therapy during protracted critical illness. , 2004, The Journal of clinical endocrinology and metabolism.
[73] E. Crouser,et al. Endotoxin-induced mitochondrial damage correlates with impaired respiratory activity , 2002, Critical care medicine.
[74] C. Kahn,et al. Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. , 2000, The Journal of clinical investigation.
[75] D. Connolly,et al. Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-alpha, but not by insulin. , 1990, The Journal of biological chemistry.
[76] P. Gaffney,et al. Changes in fibrinolysis in the intensive care patient. , 1987, Thrombosis research.
[77] T. Evans,et al. Mechanisms of organ dysfunction in critical illness: report from a Round Table Conference held in Brussels , 2002, Intensive Care Medicine.
[78] C. Carvalho,et al. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. , 1998, The New England journal of medicine.
[79] U. Das. Is insulin an antiinflammatory molecule? , 2001, Nutrition.
[80] J Herlitz,et al. Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. , 1995, Journal of the American College of Cardiology.
[81] C. Wolf‐peeters,et al. Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients , 2005, The Lancet.
[82] M. Seppälä,et al. Insulin regulates the serum levels of low molecular weight insulin-like growth factor-binding protein. , 1988, The Journal of clinical endocrinology and metabolism.
[83] F. Gao,et al. Ischemia-Reperfusion : The Roles of PI 3-Kinase , Akt , and Endothelial Nitric Oxide Nitric Oxide Mediates the Antiapoptotic Effect of Insulin in Myocardial , 2002 .
[84] Dieter Mesotten,et al. Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy. , 2004, The Journal of clinical endocrinology and metabolism.
[85] Y. Mao,et al. Sustained endotoxemia leads to marked down-regulation of early steps in the insulin-signaling cascade , 2001, Critical care medicine.
[86] J Ean,et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. , 2001, The New England journal of medicine.
[87] D. Stuehr,et al. Dynamics of protein nitration in cells and mitochondria. , 2004, American journal of physiology. Heart and circulatory physiology.
[88] Bruce M. Spiegelman,et al. Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction , 2003, Nature.
[89] G. Mariani,et al. Coagulation and fibrinolytic system impairment in insulin dependent diabetes mellitus. , 1992, Thrombosis research.
[90] O. Ljungqvist,et al. Insulin resistance: a marker of surgical stress. , 1999, Current opinion in clinical nutrition and metabolic care.
[91] J. Wahren,et al. Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in insulin-dependent diabetes. , 1994, The Journal of clinical endocrinology and metabolism.
[92] K. Feingold,et al. Infection and inflammation-induced proatherogenic changes of lipoproteins. , 2000, The Journal of infectious diseases.