Effects of coagulation on the two-phase peristaltic pumping of magnetized prandtl biofluid through an endoscopic annular geometry containing a porous medium

Abstract In this article, motivated by more accurate simulation of electromagnetic blood flow in annular vessel geometries in intravascular thrombosis, a mathematical model is developed for elucidating the effects of coagulation (i.e., a blood clot) on peristaltically induced motion of an electrically-conducting (magnetized) Prandtl fluid physiological suspension through a non-uniform annulus containing a homogenous porous medium. Magnetohydrodynamics is included owing to the presence of iron in the hemoglobin molecule and also the presence of ions in real blood. Hall current which generates a secondary (cross) flow at stronger magnetic field is also considered in the present study. A small annular tube (endoscopic) with sinusoidal peristaltic waves traveling along the inner and outer walls at constant velocity with a clot present is analyzed. The governing conservation equations which comprise the continuity and momentum equations for the fluid phase and particle phase are simplified under lubrication approximations (long wavelength and creeping flow conditions). The moving boundary value problem is normalized and solved analytically (with appropriate wall conditions) for the fluid phase and particle phase using the homotopy perturbation method (HPM) with MATHEMATICA software. Validation is conducted with MAPLE numerical quadrature. A parametric study of the influence of clot height (δ), particle volume fraction (C), Prandtl fluid material parameters (α, β), Hartmann number (M), Hall parameter (m), permeability parameter (k), peristaltic wave amplitude (φ) and wave number ( δ ¯ ) on pressure difference and wall shear (friction forces) is included. Pressure rise is elevated with clot height, medium permeability and Prandtl rheological material parameters whereas it is reduced with increasing particle volume fraction and magnetic Hartmann number. Friction forces on the outer and inner tubes of the endoscope annulus are enhanced with clot height and particle volume fraction whereas they are decreased with Prandtl rheological material parameters, Hall parameter and permeability parameter. The simulations provide a good benchmark for more general computational fluid dynamics studies of magnetic endoscopic multi-phase peristaltic pumping.

[1]  Mohammad Mehdi Rashidi,et al.  HOMOTOPY SIMULATION OF TWO-PHASE THERMO-HEMODYNAMIC FILTRATION IN A HIGH PERMEABILITY BLOOD PURIFICATION DEVICE , 2013 .

[2]  Noreen Sher Akbar,et al.  MHD EYRING–PRANDTL FLUID FLOW WITH CONVECTIVE BOUNDARY CONDITIONS IN SMALL INTESTINES , 2013 .

[3]  Ahmed Hassanein,et al.  Multiphase hemodynamic simulation of pulsatile flow in a coronary artery. , 2006, Journal of biomechanics.

[4]  O. Bég,et al.  A Numerical Study of Oscillating Peristaltic Flow of Generalized Maxwell Viscoelastic Fluids Through a Porous Medium , 2012, Transport in Porous Media.

[5]  N. Akbar,et al.  Peristaltic flow of a Phan-Thien-Tanner nanofluid in a diverging tube , 2012 .

[6]  A. Hilton,et al.  Magnetic drive system for a new centrifugal rotary blood pump. , 2008, Artificial organs.

[7]  F. Carpi Magnetic capsule endoscopy: the future is around the corner , 2010, Expert review of medical devices.

[8]  S. Das,et al.  Peristaltic flow of viscoelastic fluid with fractional Maxwell model through a channel , 2010, Appl. Math. Comput..

[9]  A. Zeeshan,et al.  Mathematical study of peristaltic propulsion of solid-liquid multiphase flow with a biorheological fluid as the base fluid in a duct , 2017 .

[10]  W. Nichols,et al.  McDonald's Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles , 1998 .

[11]  Paolo Dario,et al.  Magnetically-driven medical robots: An analytical magnetic model for endoscopic capsules design , 2018 .

[12]  Jianfeng Li,et al.  Numerical flow simulation in the post-endoscopic sinus surgery nasal cavity , 2008, Medical & Biological Engineering & Computing.

[13]  Kh. S. Mekheimer,et al.  PARTICULATE SUSPENSION FLOW INDUCED BY SINUSOIDAL PERISTALTIC WAVES THROUGH ECCENTRIC CYLINDERS: THREAD ANNULAR , 2013 .

[14]  Scott Hagen,et al.  Hemodynamics , 2021, Pediatric Critical Care.

[15]  L. Wurfel Mcdonald S Blood Flow In Arteries Theoretical Experimental And Clinical Principles , 2016 .

[16]  T. Hayat,et al.  Homogeneous–heterogeneous reactions in peristaltic flow of Prandtl fluid with thermal radiation , 2017 .

[17]  Barbara M. Johnston,et al.  Non-Newtonian blood flow in human right coronary arteries: steady state simulations. , 2004, Journal of biomechanics.

[18]  Tasawar Hayat,et al.  Endoscope effects on MHD peristaltic flow of a power-law fluid , 2006 .

[19]  Kh. S. Mekheimer,et al.  Peristaltic Motion of a Particle-Fluid Suspension in a Planar Channel , 1998 .

[20]  Dharmendra Tripathi,et al.  Electrothermal transport of nanofluids via peristaltic pumping in a finite micro-channel: Effects of Joule heating and Helmholtz-Smoluchowski velocity , 2017 .

[21]  Ji-Huan He Homotopy perturbation technique , 1999 .

[22]  Subin Solomen,et al.  Biomechanics of Circulation , 2018 .

[23]  Dharmendra Tripathi,et al.  MAGNETOHYDRODYNAMIC PERISTALTIC FLOW OF A COUPLE STRESS FLUID THROUGH COAXIAL CHANNELS CONTAINING A POROUS MEDIUM , 2012 .

[24]  Domenic D'Ambrosio,et al.  Electromagnetic Fluid Dynamics for Aerospace Applications , 2007 .

[25]  O. Bég,et al.  Slip and Hall Current Effects on Jeffrey Fluid Suspension Flow in a Peristaltic Hydromagnetic Blood Micropump , 2018, Iranian Journal of Science and Technology, Transactions of Mechanical Engineering.

[26]  Rahmat Ellahi,et al.  Study of Heat Transfer with Nonlinear Thermal Radiation on Sinusoidal Motion of Magnetic Solid Particles in a Dusty Fluid , 2016 .

[27]  Muhammad Mubashir Bhatti,et al.  Slip effects and endoscopy analysis on blood flow of particle-fluid suspension induced by peristaltic wave , 2016 .

[28]  M. M. Bhatti,et al.  HEAT AND MASS TRANSFER ANALYSIS ON PERISTALTIC FLOW OF PARTICLE–FLUID SUSPENSION WITH SLIP EFFECTS , 2017 .

[29]  Dharmendra Tripathi,et al.  Electro-magneto-hydrodynamic peristaltic pumping of couple stress biofluids through a complex wavy micro-channel , 2017 .

[30]  K. Mekheimer,et al.  Peristaltic transport of a particle--fluid suspension through a uniform and non-uniform annulus , 2008 .

[31]  Shanbao Cheng,et al.  Miniaturization of a magnetically levitated axial flow blood pump. , 2010, Artificial organs.

[32]  Zhigang Yang,et al.  Heat and mass transfer analysis on MHD blood flow of Casson fluid model due to peristaltic wave , 2016 .

[33]  D. Tripathi Numerical study on peristaltic flow of generalized burgers' fluids in uniform tubes in the presence of an endoscope , 2011 .

[34]  Ahmet Yildirim,et al.  Effects of partial slip on the peristaltic flow of a MHD Newtonian fluid in an asymmetric channel , 2010, Math. Comput. Model..

[35]  Asim Siddiqui,et al.  Peristaltic flow of a second-order fluid in tubes , 1994 .

[36]  C. Higgins,et al.  MR measurement of blood flow in the cardiovascular system. , 1992, AJR. American journal of roentgenology.

[37]  Arshad Riaz,et al.  The influence of wall flexibility on unsteady peristaltic flow of Prandtl fluid in a three dimensional rectangular duct , 2014, Appl. Math. Comput..

[38]  Mohammad Mehdi Rashidi,et al.  Homotopy perturbation study of nonlinear vibration of Von Karman rectangular plates , 2012 .

[39]  Sohail Nadeem,et al.  Series Solutions of Magnetohydrodynamic Peristaltic Flow of a Jeffrey Fluid in Eccentric Cylinders , 2013 .

[40]  P. Nagarani,et al.  Peristaltic flow of a Casson fluid in an annulus , 2012, Korea-Australia Rheology Journal.

[41]  O. Bég,et al.  NUMERICAL SIMULATION OF MARANGONI MAGNETOHYDRODYNAMIC BIO-NANOFLUID CONVECTION FROM A NON-ISOTHERMAL SURFACE WITH MAGNETIC INDUCTION EFFECTS: A BIO-NANOMATERIAL MANUFACTURING TRANSPORT MODEL , 2014 .

[42]  Mohammad Mehdi Rashidi,et al.  Differential transform semi-numerical analysis of biofluid-particle suspension flow and heat transfer in non-Darcian porous media , 2013, Computer methods in biomechanics and biomedical engineering.

[43]  O. Anwar Bég,et al.  Network and Nakamura tridiagonal computational simulation of electrically-conducting biopolymer micro-morphic transport phenomena , 2014, Comput. Biol. Medicine.

[44]  M. J. Uddin,et al.  Computational solutions for non-isothermal, nonlinear magneto-convection in porous media with hall/ionslip currents and ohmic dissipation , 2016 .

[45]  Ahmed Zeeshan,et al.  Heat transfer analysis on peristaltically induced motion of particle-fluid suspension with variable viscosity: Clot blood model , 2016, Comput. Methods Programs Biomed..

[46]  K. Mekheimer,et al.  Peristaltic flow of a couple stress fluid in an annulus: Application of an endoscope , 2008 .

[47]  O. Bég,et al.  NETWORK NUMERICAL ANALYSIS OF OPTICALLY THICK HYDROMAGNETIC SLIP FLOW FROM A POROUS SPINNING DISK WITH RADIATION FLUX, VARIABLE THERMOPHYSICAL PROPERTIES, AND SURFACE INJECTION EFFECTS , 2010 .

[48]  M. J. Uddin,et al.  Radiative Convective Nanofluid Flow Past a Stretching/Shrinking Sheet with Slip Effects , 2015 .

[49]  Shyh-Hau Wang,et al.  Assessment of Blood Coagulation Under Various Flow Conditions With Ultrasound Backscattering , 2007, IEEE Transactions on Biomedical Engineering.

[50]  G. S. Sekhon,et al.  Pumping action on blood by a magnetic field , 1977 .

[51]  O. Bég,et al.  Numerical study of magnetohydrodynamic viscous plasma flow in rotating porous media with Hall currents and inclined magnetic field influence , 2010 .

[52]  C. L. Tien,et al.  Boundary and inertia effects on flow and heat transfer in porous media , 1981 .

[53]  N. S. Gad Effect of Hall currents on interaction of pulsatile and peristaltic transport induced flows of a particle-fluid suspension , 2011, Appl. Math. Comput..

[54]  Thomas D. Brown,et al.  Computational and experimental investigations of two-dimensional nonlinear peristaltic flows , 1977, Journal of Fluid Mechanics.

[55]  M. R. Kaimal,et al.  On Peristaltic Pumping , 1978 .

[56]  Keller Box and Smoothed Particle Hydrodynamic Numerical Simulation of Two-Phase Transport in Blood Purification Auto- Transfusion Dialysis Hybrid Device with Stokes and Darcy Number Effects , 2013 .

[57]  R. Carretta McDonaldʼs Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles , 1998 .

[58]  R. Schmid,et al.  Magnetic endoscope imaging in single‐balloon enteroscopy , 2015, Digestive Endoscopy.

[59]  D. Xia A Bionic Artificial Heart Blood Pump Driven by Permanent Magnet Located Outside Human Body , 2012, IEEE Transactions on Applied Superconductivity.

[60]  N. Akbar,et al.  Effects of heat and mass transfer on peristaltic flow of a nanofluid between eccentric cylinders , 2014, Applied Nanoscience.

[61]  Kuppalapalle Vajravelu,et al.  Peristaltic flow and heat transfer in a vertical porous annulus, with long wave approximation , 2007 .

[62]  Abd El Hakeem Abd El Naby,et al.  Effects of a Fluid with Variable Viscosity and an Endoscope on Peristaltic Motion , 2003 .

[63]  Mohammad Mehdi Rashidi,et al.  Magnetohydrodynamic biorheological transport phenomena in a porous medium: A simulation of magnetic blood flow control and filtration , 2011 .

[64]  J. C. Misra,et al.  PERISTALTIC TRANSPORT OF A COUPLE STRESS FLUID: SOME APPLICATIONS TO HEMODYNAMICS , 2010, 1006.0177.

[65]  M. M. Bhatti,et al.  Analytical study on liquid-solid particles interaction in the presence of heat and mass transfer through a wavy channel , 2018 .

[66]  T. Hayat,et al.  PERISTALTIC FLOW OF COUPLE-STRESS FLUID WITH HEAT AND MASS TRANSFER: AN APPLICATION IN BIOMEDICINE , 2015 .