EF-hand motifs of diacylglycerol kinase α interact intra-molecularly with its C1 domains

[1]  John Kuriyan,et al.  Structural studies on the regulation of Ca2+/calmodulin dependent protein kinase II. , 2013, Current opinion in structural biology.

[2]  Hiromichi Sakai,et al.  Calcium negatively regulates an intramolecular interaction between the N-terminal recoverin homology and EF-hand motif domains and the C-terminal C1 and catalytic domains of diacylglycerol kinase α. , 2012, Biochemical and biophysical research communications.

[3]  Y. Maehara,et al.  Diacylglycerol kinase alpha enhances hepatocellular carcinoma progression by activation of Ras-Raf-MEK-ERK pathway. , 2012, Journal of hepatology.

[4]  R. Epand,et al.  Regulation and functions of diacylglycerol kinases. , 2011, Chemical reviews.

[5]  Q. Wei,et al.  Calcineurin regulatory subunit B is a unique calcium sensor that regulates calcineurin in both calcium‐dependent and calcium‐independent manner , 2009, Proteins.

[6]  M. Kai,et al.  Diacylglycerol kinases as emerging potential drug targets for a variety of diseases. , 2008, Current drug targets.

[7]  I. Mérida,et al.  Diacylglycerol kinases: at the hub of cell signalling. , 2008, The Biochemical journal.

[8]  M. Kai,et al.  Phorbol ester and hydrogen peroxide synergistically induce the interaction of diacylglycerol kinase γ with the Src homology 2 and C1 domains of β2-chimaerin , 2008 .

[9]  I. Mérida,et al.  Role of the Diacylglycerol Kinase α-Conserved Domains in Membrane Targeting in Intact T Cells* , 2007, Journal of Biological Chemistry.

[10]  M. Kai,et al.  Diacylglycerol kinases: why so many of them? , 2007, Biochimica et biophysica acta.

[11]  M. Kai,et al.  Diacylglycerol kinase α suppresses tumor necrosis factor-α-induced apoptosis of human melanoma cells through NF-κB activation , 2007 .

[12]  I. Mérida,et al.  Role of the diacylglycerol kinase alpha-conserved domains in membrane targeting in intact T cells. , 2007, Journal of Biological Chemistry.

[13]  M. Topham,et al.  Disruption of diacylglycerol metabolism impairs the induction of T cell anergy , 2006, Nature Immunology.

[14]  J. Stone,et al.  T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-α , 2006, Nature Immunology.

[15]  M. Kazanietz,et al.  C1 domains exposed: from diacylglycerol binding to protein-protein interactions. , 2006, Biochimica et biophysica acta.

[16]  Y. Hozumi,et al.  Diacylglycerol, phosphatidic acid, and the converting enzyme, diacylglycerol kinase, in the nucleus. , 2006, Biochimica et biophysica acta.

[17]  M. Berchtold.  Evolution of EF-hand calcium-modulated proteins. V. The genes encoding EF-hand proteins are not clustered in mammalian genomes , 1993, Journal of Molecular Evolution.

[18]  Robert H. Kretsinger,et al.  Evolution of EF-hand calcium-modulated proteins. I. Relationships based on amino acid sequences , 1990, Journal of Molecular Evolution.

[19]  L. Saidi,et al.  Structural Mechanism for Lipid Activation of the Rac-Specific GAP, β2-Chimaerin , 2004, Cell.

[20]  K. Houkin,et al.  Diacylglycerol Kinase γ Serves as an Upstream Suppressor of Rac1 and Lamellipodium Formation* , 2004, Journal of Biological Chemistry.

[21]  Gaetano T Montelione,et al.  Cold-shock induced high-yield protein production in Escherichia coli , 2004, Nature Biotechnology.

[22]  Nils Brose,et al.  Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters , 2002, Journal of Cell Science.

[23]  M. Maki,et al.  ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner. , 2002, Biochemical and biophysical research communications.

[24]  J. P. Walsh,et al.  A Domain with Homology to Neuronal Calcium Sensors Is Required for Calcium-dependent Activation of Diacylglycerol Kinase α* , 2000, The Journal of Biological Chemistry.

[25]  W. V. van Blitterswijk,et al.  Properties and functions of diacylglycerol kinases. , 2000, Cellular signalling.

[26]  P. Comoglio,et al.  Src‐mediated activation of α‐diacylglycerol kinase is required for hepatocyte growth factor‐induced cell motility , 2000, The EMBO journal.

[27]  I. Mérida,et al.  Diacylglycerol kinase inhibition prevents IL-2-induced G1 to S transition through a phosphatidylinositol-3 kinase-independent mechanism. , 1999, Journal of immunology.

[28]  M. Wakelam,et al.  Diacylglycerols and phosphatidates: which molecular species are intracellular messengers? , 1998, Trends in biochemical sciences.

[29]  N. Matsushima,et al.  EF-hand motifs of alpha, beta and gamma isoforms of diacylglycerol kinase bind calcium with different affinities and conformational changes. , 1997, The Biochemical journal.

[30]  D. English,et al.  Phosphatidic acid: a lipid messenger involved in intracellular and extracellular signalling. , 1996, Cellular signalling.

[31]  N. Matsushima,et al.  EF-hand motifs of a , b and c isoforms of diacylglycerol kinase bind calcium with different affinities and conformational changes , 1996 .

[32]  J. Exton.  Phosphatidylcholine breakdown and signal transduction. , 1994, Biochimica et biophysica acta.

[33]  K. Goto,et al.  Gene cloning, sequence, expression and in situ localization of 80 kDa diacylglycerol kinase specific to oligodendrocyte of rat brain. , 1992, Brain research. Molecular brain research.

[34]  K. Yamada,et al.  The regulatory role of EF-hand motifs of pig 80K diacylglycerol kinase as assessed using truncation and deletion mutants. , 1991, Biochemical and biophysical research communications.

[35]  K. Yamada,et al.  Porcine 80-kDa diacylglycerol kinase is a calcium-binding and calcium/phospholipid-dependent enzyme and undergoes calcium-dependent translocation. , 1991, The Journal of biological chemistry.

[36]  A Bairoch,et al.  EF‐hand motifs in inositol phospholipid‐specific phospholipase C , 1990, FEBS letters.

[37]  C. Yokoyama,et al.  Porcine diacylglycerol kinase sequence has zinc finger and E–F hand motifs , 1990, Nature.

[38]  Keiko Yamada,et al.  Immunoquantitation of 80 kDa diacylglycerol kinase in pig and human lymphocytes and several other cells , 1989, FEBS letters.

[39]  H. Kanoh,et al.  Occurrence of immunoreactive 80 kDa and non-immunoreactive diacylglycerol kinases in different pig tissues. , 1988, Biochemical Journal.

[40]  H. Kawasaki,et al.  Evolutionary origin of a calcium-dependent protease by fusion of genes for a thiol protease and a calcium-binding protein? , 1984, Nature.

[41]  T. Murachi.  Calcium-dependent proteinases and specific inhibitors: calpain and calpastatin. , 1984, Biochemical Society symposium.

[42]  Kretsinger Rh.  The informational role of calcium in the cytosol. , 1979 .

[43]  R. Kretsinger.  The informational role of calcium in the cytosol. , 1979, Advances in cyclic nucleotide research.