论文信息 - Combined visible light optical coherence microscopy and fluorescence imaging setup to investigate 5-aminolevulinic acid postive glioma samples

Combined visible light optical coherence microscopy and fluorescence imaging setup to investigate 5-aminolevulinic acid postive glioma samples

5-aminolevulinic acid positive brain tumor samples were investigated with a multimodal visible light optical coherence microscope (OCM) and fluorescence imaging (FI) setup. Tumor specific contrast was achieved by the FI part while the three-dimensional tissue morphology was assessed by the OCM part of the setup.

[1] Daniela Prayer,et al. 5-Aminolevulinic Acid Induced Fluorescence Is a Powerful Intraoperative Marker for Precise Histopathological Grading of Gliomas with Non-Significant Contrast-Enhancement , 2013, PloS one.

[2] Harry Moseley,et al. Modelling fluorescence in clinical photodynamic therapy , 2012, Photochemical & Photobiological Sciences.

[3] Johannes E. Schindelin,et al. Fiji: an open-source platform for biological-image analysis , 2012, Nature Methods.

[4] Wolfgang Drexler,et al. Optical coherence tomography: Technology and applications , 2013, 2013 Conference on Lasers & Electro-Optics Europe & International Quantum Electronics Conference CLEO EUROPE/IQEC.

[5] D. Barone,et al. Image guided surgery for the resection of brain tumours. , 2014, The Cochrane database of systematic reviews.

[6] O. Gallego,et al. Nonsurgical treatment of recurrent glioblastoma. , 2015, Current oncology.

[7] Ke Si,et al. Optical Brain Imaging: A Powerful Tool for Neuroscience , 2017, Neuroscience Bulletin.

[8] Christoph K. Hitzenberger,et al. Spectroscopic imaging with spectral domain visible light optical coherence microscopy in Alzheimer’s disease brain samples , 2017, Biomedical optics express.

[9] Marco Augustin,et al. Assessment of pathological features in Alzheimer’s disease brain tissue with a large field-of-view visible-light optical coherence microscope , 2018, Neurophotonics.