Validation of an isotope dilution gas chromatography-mass spectrometry method for analysis of 7-oxygenated campesterol and sitosterol in human serum.

[1]  A. Maguire,et al.  Cytotoxic and apoptotic effects of the oxidized derivatives of stigmasterol in the U937 human monocytic cell line. , 2010, Journal of agricultural and food chemistry.

[2]  R. Mensink,et al.  Plant stanols dose-dependently decrease LDL-cholesterol concentrations, but not cholesterol-standardized fat-soluble antioxidant concentrations, at intakes up to 9 g/d. , 2010, The American journal of clinical nutrition.

[3]  K. Tan,et al.  ABCG1 mediated oxidized LDL-derived oxysterol efflux from macrophages. , 2009, Biochemical and biophysical research communications.

[4]  J. Jolles,et al.  Consuming functional foods enriched with plant sterol or stanol esters for 85 weeks does not affect neurocognitive functioning or mood in statin-treated hypercholesterolemic individuals. , 2009, The Journal of nutrition.

[5]  Masao Sato,et al.  A Comparison of the Potential Unfavorable Effects of Oxycholesterol and Oxyphytosterol in Mice: Different Effects, on Cerebral 24S-Hydroxychoelsterol and Serum Triacylglycerols Levels , 2008, Bioscience, biotechnology, and biochemistry.

[6]  U. Laufs,et al.  Controversial role of plant sterol esters in the management of hypercholesterolaemia , 2008, European heart journal.

[7]  M. Endres,et al.  Vascular effects of diet supplementation with plant sterols. , 2008, Journal of the American College of Cardiology.

[8]  D. Ansorena,et al.  Validation of a gas chromatography-mass spectrometry method for the analysis of sterol oxidation products in serum. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[9]  L. Johnsson,et al.  No evidence of genotoxic effect in vivo of the phytosterol oxidation products triols and epoxides. , 2007, Toxicology letters.

[10]  T. Sudhop,et al.  The lipid-lowering effect of ezetimibe in pure vegetarians Published, JLR Papers in Press, September 11, 2006. , 2006, Journal of Lipid Research.

[11]  F. Maxfield,et al.  Role of cholesterol and lipid organization in disease , 2005, Nature.

[12]  S. Grundy,et al.  History and development of plant sterol and stanol esters for cholesterol-lowering purposes. , 2005, The American journal of cardiology.

[13]  T. Sudhop,et al.  Cholesterol and plant sterol absorption: recent insights. , 2005, The American journal of cardiology.

[14]  T. Sudhop,et al.  Sterol transporters: targets of natural sterols and new lipid lowering drugs. , 2005, Pharmacology & therapeutics.

[15]  I. Ichi,et al.  Erratum: Phytosterol oxidation products are absorbed in the intestinal lymphatics in rats but do not accelerate atherosclerosis in apolipoprotein E-deficient mice (Journal of Nutrition (2004) 134 (1690-1696)) , 2004 .

[16]  I. Ichi,et al.  Phytosterol oxidation products are absorbed in the intestinal lymphatics in rats but do not accelerate atherosclerosis in apolipoprotein E-deficient mice. , 2004, The Journal of nutrition.

[17]  S. Métairon,et al.  Both free and esterified plant sterols reduce cholesterol absorption and the bioavailability of β-carotene and α-tocopherol in normocholesterolemic humans , 2004 .

[18]  L. Martine,et al.  Gas chromatographic separation and mass spectrometric identification of mixtures of oxyphytosterol and oxycholesterol derivatives application to a phytosterol-enriched food. , 2004, Journal of chromatography. A.

[19]  K. Fassbender,et al.  High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs , 2004, Steroids.

[20]  L. Martine,et al.  Oxyphytosterols are present in plasma of healthy human subjects , 2004, British Journal of Nutrition.

[21]  D. Townsend,et al.  Phytosterols in the prevention of human pathologies. , 2003, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[22]  L. Conte,et al.  Presence of phytosterol oxides in crude vegetable oils and their fate during refining. , 2003, Journal of agricultural and food chemistry.

[23]  K. H. Carpenter.  Good COP, bad COP: an unsolved murder. Are dietary cholesterol oxidation products guilty of atherogenicity? , 2002, British Journal of Nutrition.

[24]  K. Williams,et al.  Atherosclerosis and Inflammation , 2002, Science.

[25]  R. Mensink,et al.  Oxidized plant sterols in human serum and lipid infusions as measured by combined gas-liquid chromatography-mass spectrometry. , 2001, Journal of Lipid Research.

[26]  G. Fenner,et al.  Comparative effects of phytosterol oxides and cholesterol oxides in cultured macrophage-derived cell lines. , 2001, Journal of agricultural and food chemistry.

[27]  P. Dutta,et al.  Plant sterols in vegetables and fruits commonly consumed in Sweden , 1999, European journal of nutrition.

[28]  Andrew J. Brown,et al.  Oxysterols and atherosclerosis. , 1999, Atherosclerosis.

[29]  R. Ross,et al.  Atherosclerosis is an Inflammatory Disease , 1998 .

[30]  D. Lütjohann,et al.  Phytosterolaemia: diagnosis, characterization and therapeutical approaches. , 1997, Annals of medicine.

[31]  U. Diczfalusy,et al.  The oxysterols cholest-5-ene-3β,4α-diol, cholest-5-ene-3β,4β-diol and cholestane-3β,5α,6α-triol are formed during in vitro oxidation of low density lipoprotein, and are present in human atherosclerotic plaques , 1996 .

[32]  E. Vartiainen,et al.  Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population. , 1995, The New England journal of medicine.

[33]  T. Senge,et al.  Randomised, placebo-controlled, double-blind clinical trial of β-sitosterol in patients with benign prostatic hyperplasia , 1995, The Lancet.

[34]  P. J. Jones,et al.  Dietary phytosterols: a review of metabolism, benefits and side effects. , 1995, Life sciences.

[35]  K. Bloch.  Sterol molecule: structure, biosynthesis, and function , 1992, Steroids.

[36]  S. Grundy,et al.  Metabolism of β-sitosterol in man , 1970 .

[37]  R. Mensink,et al.  Biological effects of oxidized phytosterols: a review of the current knowledge. , 2008, Progress in lipid research.

[38]  R. Mensink,et al.  Effects of long-term plant sterol or stanol ester consumption on lipid and lipoprotein metabolism in subjects on statin treatment. , 2008, The British journal of nutrition.

[39]  Aldons J. Lusis,et al.  Atherosclerosis : Vascular biology , 2000 .