Solution structure of ERK2 binding domain of MAPK phosphatase MKP-3: structural insights into MKP-3 activation by ERK2.

[1]  J. Denu,et al.  Mechanistic Basis for Catalytic Activation of Mitogen-activated Protein Kinase Phosphatase 3 by Extracellular Signal-regulated Kinase* , 2000, The Journal of Biological Chemistry.

[2]  E. Nishida,et al.  A conserved docking motif in MAP kinases common to substrates, activators and regulators , 2000, Nature Cell Biology.

[3]  Bo Zhou,et al.  Mechanism of Mitogen-activated Protein Kinase Phosphatase-3 Activation by ERK2* , 1999, The Journal of Biological Chemistry.

[4]  Christian Griesinger,et al.  Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients , 1999 .

[5]  S. Keyse,et al.  Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation , 1999, Nature Structural Biology.

[6]  K Wüthrich,et al.  Single Transition-to-single Transition Polarization Transfer (ST2-PT) in [15N,1H]-TROSY , 1998, Journal of biomolecular NMR.

[7]  M. Muda,et al.  Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase. , 1998, Science.

[8]  Michael Nilges,et al.  Ambiguous NOEs and automated NOE assignment , 1998 .

[9]  M. Muda,et al.  The Mitogen-activated Protein Kinase Phosphatase-3 N-terminal Noncatalytic Region Is Responsible for Tight Substrate Binding and Enzymatic Specificity* , 1998, The Journal of Biological Chemistry.

[10]  S. Shoelson,et al.  Crystal Structure of the Tyrosine Phosphatase SHP-2 , 1998, Cell.

[11]  R. Riek,et al.  Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[12]  Elizabeth J. Goldsmith,et al.  Activation Mechanism of the MAP Kinase ERK2 by Dual Phosphorylation , 1997, Cell.

[13]  M. Cobb,et al.  Reconstitution of Mitogen-activated Protein Kinase Phosphorylation Cascades in Bacteria , 1997, The Journal of Biological Chemistry.

[14]  G. Nuovo,et al.  Hyperexpression of mitogen-activated protein kinase in human breast cancer. , 1997, The Journal of clinical investigation.

[15]  M. Cobb,et al.  Mitogen-activated protein kinase pathways. , 1997, Current opinion in cell biology.

[16]  A. Ashworth,et al.  The Dual Specificity Phosphatases M3/6 and MKP-3 Are Highly Selective for Inactivation of Distinct Mitogen-activated Protein Kinases* , 1996, The Journal of Biological Chemistry.

[17]  B. Neel,et al.  From Form to Function: Signaling by Protein Tyrosine Phosphatases , 1996, Cell.

[18]  J. Avruch,et al.  Sounding the Alarm: Protein Kinase Cascades Activated by Stress and Inflammation* , 1996, The Journal of Biological Chemistry.

[19]  D. Alessi,et al.  Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual‐specificity phosphatase. , 1996, The EMBO journal.

[20]  H. K. Sluss,et al.  Selective interaction of JNK protein kinase isoforms with transcription factors. , 1996, The EMBO journal.

[21]  Xiaozhong Wang,et al.  Stress-Induced Phosphorylation and Activation of the Transcription Factor CHOP (GADD153) by p38 MAP Kinase , 1996, Science.

[22]  R. Treisman,et al.  Regulation of transcription by MAP kinase cascades. , 1996, Current opinion in cell biology.

[23]  C. Der,et al.  The Mitogen-activated Protein Kinase Phosphatases PAC1, MKP-1, and MKP-2 Have Unique Substrate Specificities and Reduced Activity in Vivo toward the ERK2 sevenmaker Mutation (*) , 1996, The Journal of Biological Chemistry.

[24]  M. Muda,et al.  MKP-3, a Novel Cytosolic Protein-tyrosine Phosphatase That Exemplifies a New Class of Mitogen-activated Protein Kinase Phosphatase (*) , 1996, The Journal of Biological Chemistry.

[25]  S. Grzesiek,et al.  NMRPipe: A multidimensional spectral processing system based on UNIX pipes , 1995, Journal of biomolecular NMR.

[26]  A. Sharrocks,et al.  Integration of MAP kinase signal transduction pathways at the serum response element. , 1995, Science.

[27]  M. Karin The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases (*) , 1995, The Journal of Biological Chemistry.

[28]  E. Goldsmith,et al.  How MAP Kinases Are Regulated (*) , 1995, The Journal of Biological Chemistry.

[29]  J. Dixon,et al.  A catalytic mechanism for the dual-specific phosphatases. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[30]  S. Keyse An emerging family of dual specificity MAP kinase phosphatases. , 1995, Biochimica et biophysica acta.

[31]  L. Mahadevan,et al.  Parallel signal processing among mammalian MAPKs. , 1995, Trends in biochemical sciences.

[32]  C. Marshall,et al.  Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation , 1995, Cell.

[33]  B. Dérijard,et al.  Transcription factor ATF2 regulation by the JNK signal transduction pathway , 1995, Science.

[34]  Weontae Lee,et al.  A Suite of Triple Resonance NMR Experiments for the Backbone Assignment of 15N, 13C, 2H Labeled Proteins with High Sensitivity , 1994 .

[35]  Bruce A. Johnson,et al.  NMR View: A computer program for the visualization and analysis of NMR data , 1994, Journal of biomolecular NMR.

[36]  P. Clarke Signal Transduction: Switching off MAP kinases , 1994, Current Biology.

[37]  E. Hafen,et al.  A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways , 1994, Cell.

[38]  Kathleen Kelly,et al.  Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1 , 1994, Nature.

[39]  C. Moskaluk,et al.  PAC-1: a mitogen-induced nuclear protein tyrosine phosphatase. , 1993, Science.

[40]  M. Cobb,et al.  Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro. , 1993, The Journal of biological chemistry.

[41]  M. Carson RIBBONS 2.0 , 1991 .

[42]  J. Shabanowitz,et al.  Identification of the regulatory phosphorylation sites in pp42/mitogen‐activated protein kinase (MAP kinase). , 1991, The EMBO journal.

[43]  E. Krebs,et al.  Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. , 1991, The Journal of biological chemistry.

[44]  John G. McWhirter,et al.  Parallel signal processing , 1989 .

[45]  E. Goldsmith,et al.  Dimerization in MAP-kinase signaling. , 2000, Trends in biochemical sciences.

[46]  N. Ahn,et al.  Signal transduction through MAP kinase cascades. , 1998, Advances in cancer research.

[47]  A. Nordheim,et al.  Signalling pathways: Jack of all cascades , 1996, Current Biology.

[48]  Jonathan A. Cooper,et al.  Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast. , 1995, Current opinion in cell biology.

[49]  A. Gronenborn,et al.  Multidimensional heteronuclear nuclear magnetic resonance of proteins. , 1994, Methods in enzymology.

[50]  Axel T. Brunger,et al.  X-PLOR Version 3.1: A System for X-ray Crystallography and NMR , 1992 .

[51]  J. Richardson,et al.  The anatomy and taxonomy of protein structure. , 1981, Advances in protein chemistry.