Rs11892031[A] on chromosome 2q37 in an intronic region of the UGT1A locus is associated with urinary bladder cancer risk

[1]  Chawnshang Chang,et al.  Androgen receptor signals regulate UDP‐glucuronosyltransferases in the urinary bladder: A potential mechanism of androgen‐induced bladder carcinogenesis , 2013, Molecular carcinogenesis.

[2]  M. Thun,et al.  Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer. , 2012, Human molecular genetics.

[3]  Paolo Vineis,et al.  European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene. , 2011, Human molecular genetics.

[4]  Jian Gu,et al.  A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3. , 2011, Human molecular genetics.

[5]  Mikko Koskinen,et al.  N-glucuronidation of drugs and other xenobiotics by human and animal UDP-glucuronosyltransferases , 2011, Xenobiotica; the fate of foreign compounds in biological systems.

[6]  H. Miyamoto,et al.  1071 ANDROGEN RECEPTOR SIGNALS REGULATE UDP-GLUCURONOSYLTRANSFERASES: A POTENTIAL MECHANISM OF ANDROGEN-INDUCED BLADDER CARCINOGENESIS , 2011 .

[7]  K. Ickstadt,et al.  Genetic variants in urinary bladder cancer: collective power of the “wimp SNPs” , 2011, Archives of Toxicology.

[8]  C. Guillemette,et al.  Immunohistochemical expression of conjugating UGT1A‐derived isoforms in normal and tumoral drug‐metabolizing tissues in humans , 2011, The Journal of pathology.

[9]  William Wheeler,et al.  A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci , 2010, Nature Genetics.

[10]  Paolo Vineis,et al.  A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer , 2010, Nature Genetics.

[11]  Y. Fujii‐Kuriyama,et al.  Suppression of AhR signaling pathway is associated with the down-regulation of UDP-glucuronosyltransferases during BBN-induced urinary bladder carcinogenesis in mice. , 2010, Journal of biochemistry.

[12]  M. Manns,et al.  Interaction between Oxidative Stress Sensor Nrf2 and Xenobiotic-activated Aryl Hydrocarbon Receptor in the Regulation of the Human Phase II Detoxifying UDP-glucuronosyltransferase 1A10* , 2010, The Journal of Biological Chemistry.

[13]  Jan G. Hengstler,et al.  Susceptibility to urinary bladder cancer: relevance of rs9642880[T], GSTM1 0/0 and occupational exposure. , 2009, Pharmacogenetics and genomics.

[14]  Paolo Vineis,et al.  Sequence variants at the TERT-CLPTM1L locus associate with many cancer types , 2009, Nature Genetics.

[15]  Jian Gu,et al.  Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer , 2009, Nature Genetics.

[16]  Tony Fletcher,et al.  Sequence variant on 8q24 confers susceptibility to urinary bladder cancer , 2008, Nature Genetics.

[17]  R. Fujiwara,et al.  Expression of UGT1A and UGT2B mRNA in Human Normal Tissues and Various Cell Lines , 2008, Drug Metabolism and Disposition.

[18]  K. Golka,et al.  UDP-Glucuronosyltransferase 2B7 C802T (His268Tyr) Polymorphism in Bladder Cancer Cases , 2008, Journal of toxicology and environmental health. Part A.

[19]  T. Chakrabarti,et al.  Distribution of detoxifying genes polymorphism in Maharastrian population of central India. , 2008, Chemosphere.

[20]  H. Akaza,et al.  Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carcinogenesis. , 2007, Carcinogenesis.

[21]  G. Lemasters,et al.  The genetic and environmental factors involved in benzidine metabolism and bladder carcinogenesis in exposed workers. , 2006, Frontiers in bioscience : a journal and virtual library.

[22]  K. Golka,et al.  An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China. , 2005, Toxicological sciences : an official journal of the Society of Toxicology.

[23]  L. Frati,et al.  UDP-glucuronosyltransferases 1A expression in human urinary bladder and colon cancer by immunohistochemistry. , 2005, Oncology reports.

[24]  Mark Daly,et al.  Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..

[25]  H. Akaza,et al.  Nrf2 Is Essential for the Chemopreventive Efficacy of Oltipraz against Urinary Bladder Carcinogenesis , 2004, Cancer Research.

[26]  K. Golka,et al.  Comparative metabolic activation of benzidine and N-acetylbenzidine by prostaglandin H synthase. , 2004, Toxicology letters.

[27]  F. Hsu,et al.  Metabolism of N-acetylbenzidine and initiation of bladder cancer. , 2002, Mutation research.

[28]  C. M. Lewis,et al.  Genetic association studies: Design, analysis and interpretation , 2002, Briefings Bioinform..

[29]  L. Frati,et al.  Can down‐regulation of UDP‐glucuronosyltransferases in the urinary bladder tissue impact the risk of chemical carcinogenesis? , 2001, International journal of cancer.

[30]  R. Tukey,et al.  Human UDP-glucuronosyltransferases: metabolism, expression, and disease. , 2000, Annual review of pharmacology and toxicology.

[31]  M. Ciotti,et al.  Glucuronidation of benzidine and its metabolites by cDNA-expressed human UDP-glucuronosyltransferases and pH stability of glucuronides. , 1999, Carcinogenesis.

[32]  R. Freudenthal,et al.  Determining the Potential of Aromatic Amines to Induce Cancer of the Urinary Bladder , 1999 .

[33]  M. Manns,et al.  Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus. , 1999, The Biochemical journal.

[34]  W D Plummer,et al.  Power and sample size calculations for studies involving linear regression. , 1998, Controlled clinical trials.

[35]  M. Green,et al.  Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins. , 1998, Drug metabolism and disposition: the biological fate of chemicals.

[36]  M. Manns,et al.  Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue. , 1997, Molecular pharmacology.

[37]  S. R. Babu,et al.  Glucuronidation of N-hydroxy metabolites of N-acetylbenzidine. , 1995, Carcinogenesis.

[38]  S. R. Babu,et al.  Glucuronidation of N-acetylbenzidine by human liver. , 1994, Drug metabolism and disposition: the biological fate of chemicals.

[39]  Erich Latniak,et al.  Das Ruhrgebiet im Umbruch , 1994 .

[40]  W. Dupont,et al.  Power and sample size calculations. A review and computer program. , 1990, Controlled clinical trials.