The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress.

[1]  P. Cohen,et al.  Mitochondrially derived peptides as novel regulators of metabolism , 2017, The Journal of physiology.

[2]  E. Ma,et al.  AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species. , 2017, Cell reports.

[3]  Cassandra Willyard.  The drug-resistant bacteria that pose the greatest health threats , 2017, Nature.

[4]  Cole M. Haynes,et al.  The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR , 2016, Current Biology.

[5]  Huanyu Lu,et al.  Mitochondria related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK activation. , 2016, Biochemical and biophysical research communications.

[6]  Fátima Sánchez-Cabo,et al.  Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing , 2016, Nature.

[7]  C. Gustafsson,et al.  Maintenance and Expression of Mammalian Mitochondrial DNA. , 2016, Annual review of biochemistry.

[8]  B. Meyer,et al.  Mitochondrial Stress Induces Chromatin Reorganization to Promote Longevity and UPRmt , 2016, Cell.

[9]  Evan G. Williams,et al.  Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity , 2016, Cell.

[10]  Ja Hyun Koo,et al.  AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550 , 2016, Molecular and Cellular Biology.

[11]  Lior Pachter,et al.  Near-optimal probabilistic RNA-seq quantification , 2016, Nature Biotechnology.

[12]  Yeji Kim,et al.  AMPK activators: mechanisms of action and physiological activities , 2016, Experimental & Molecular Medicine.

[13]  J. Auwerx,et al.  Mitonuclear communication in homeostasis and stress , 2016, Nature Reviews Molecular Cell Biology.

[14]  J. Nunnari,et al.  The Emerging Network of Mitochondria-Organelle Contacts. , 2016, Molecular cell.

[15]  A. Brunet,et al.  AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs. , 2016, Trends in cell biology.

[16]  A. Whitmarsh,et al.  Mitochondrial Proteins Moonlighting in the Nucleus. , 2015, Trends in biochemical sciences.

[17]  C. S. St. Croix,et al.  In Vivo Immuno‐Spin Trapping: Imaging the Footprints of Oxidative Stress , 2015, Current protocols in cytometry.

[18]  Garry Hamilton.  The hidden risks for ‘three-person’ babies , 2015, Nature.

[19]  A. Lucia,et al.  The mitochondrial‐derived peptide MOTS‐c: a player in exceptional longevity? , 2015, Aging cell.

[20]  N. Chandel.  Evolution of Mitochondria as Signaling Organelles. , 2015, Cell metabolism.

[21]  J. Auwerx,et al.  The mitochondrial unfolded protein response—synchronizing genomes. , 2015, Current opinion in cell biology.

[22]  Changhan Lee,et al.  The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. , 2015, Cell metabolism.

[23]  D. Corey,et al.  Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading , 2014, Nature Protocols.

[24]  J. Hayes,et al.  The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. , 2014, Trends in biochemical sciences.

[25]  P. Cohen,et al.  Humanin: a harbinger of mitochondrial-derived peptides? , 2013, Trends in Endocrinology & Metabolism.

[26]  A. Bratić,et al.  The role of mitochondria in aging. , 2013, The Journal of clinical investigation.

[27]  Emma Lundberg,et al.  Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells , 2013, Nature Methods.

[28]  Andrew J. Seal,et al.  Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction☆ , 2013, Redox biology.

[29]  Q. Ma.  Role of nrf2 in oxidative stress and toxicity. , 2013, Annual review of pharmacology and toxicology.

[30]  L. Galluzzi,et al.  Mitochondria: master regulators of danger signalling , 2012, Nature Reviews Molecular Cell Biology.

[31]  K. Nakayama,et al.  Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks , 2012, Nucleic acids research.

[32]  D. Hardie,et al.  AMPK: a nutrient and energy sensor that maintains energy homeostasis , 2012, Nature Reviews Molecular Cell Biology.

[33]  G. Ammerer,et al.  Controlling gene expression in response to stress , 2011, Nature Reviews Genetics.

[34]  B. Viollet,et al.  Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status , 2011, Diabetologia.

[35]  R. Mann,et al.  Origins of specificity in protein-DNA recognition. , 2010, Annual review of biochemistry.

[36]  C. Glass,et al.  Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. , 2010, Molecular cell.

[37]  J. Chan,et al.  Role of Nrf1 in antioxidant response element-mediated gene expression and beyond. , 2010, Toxicology and applied pharmacology.

[38]  Cole Trapnell,et al.  Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.

[39]  Israel Steinfeld,et al.  BMC Bioinformatics BioMed Central , 2008 .

[40]  Clifford A. Meyer,et al.  Model-based Analysis of ChIP-Seq (MACS) , 2008, Genome Biology.

[41]  R. Nussinov,et al.  Principles of protein-protein interactions: what are the preferred ways for proteins to interact? , 2008, Chemical reviews.

[42]  Anja Voigt,et al.  Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. , 2007, Cell metabolism.

[43]  Zohar Yakhini,et al.  Discovering Motifs in Ranked Lists of DNA Sequences , 2007, PLoS Comput. Biol..

[44]  L. Scorrano,et al.  Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts , 2007, Nature Protocols.

[45]  B. Bassler,et al.  Quorum sensing: cell-to-cell communication in bacteria. , 2005, Annual review of cell and developmental biology.

[46]  M. Roden,et al.  Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions? , 2004, Diabetes.

[47]  M. Hodel,et al.  Dissection of a Nuclear Localization Signal* , 2001, The Journal of Biological Chemistry.

[48]  D. Hardie,et al.  5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? , 1995, European journal of biochemistry.

[49]  T. Kadowaki,et al.  Use of polymerase chain reaction catalyzed by Taq DNA polymerase for site-specific mutagenesis. , 1989, Gene.

[50]  K. Bomsztyk,et al.  Protocol for the fast chromatin immunoprecipitation (ChIP) method , 2006, Nature Protocols.