Recovery from checkpoint-mediated arrest after repair of a double-strand break requires Srs2 helicase.

[1]  M. Hannan,et al.  Caffeine enhancement of radiation killing in different strains of Saccharomyces cerevisiae , 1977, Molecular and General Genetics MGG.

[2]  John Rouse,et al.  Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo. , 2002, Molecular cell.

[3]  S. Elledge,et al.  Regulation of the Bub2/Bfa1 GAP Complex by Cdc5 and Cell Cycle Checkpoints , 2001, Cell.

[4]  D. Toczyski,et al.  Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. , 2001, Genes & development.

[5]  Kunihiro Matsumoto,et al.  Recruitment of Mec1 and Ddc1 Checkpoint Proteins to Double-Strand Breaks Through Distinct Mechanisms , 2001, Science.

[6]  J. Haber,et al.  The Saccharomyces recombination protein Tid1p is required for adaptation from G2/M arrest induced by a double-strand break , 2001, Current Biology.

[7]  C. Gilbert,et al.  Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. , 2001, Molecular cell.

[8]  Karl Mechtler,et al.  Phosphorylation of the Cohesin Subunit Scc1 by Polo/Cdc5 Kinase Regulates Sister Chromatid Separation in Yeast , 2001, Cell.

[9]  C. Newlon,et al.  RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site. , 2001, Genes & development.

[10]  M. Emond,et al.  Loss of Werner syndrome protein function promotes aberrant mitotic recombination. , 2001, Genes & development.

[11]  J. Haber,et al.  Genetic Requirements for RAD51- andRAD54-Independent Break-Induced Replication Repair of a Chromosomal Double-Strand Break , 2001, Molecular and Cellular Biology.

[12]  Katsunori Sugimoto,et al.  Pie1, a Protein Interacting with Mec1, Controls Cell Growth and Checkpoint Responses in Saccharomyces cerevisiae , 2001, Molecular and Cellular Biology.

[13]  J. Haber,et al.  Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. , 2001, Molecular cell.

[14]  H. Klein.  Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Delta with other DNA repair genes in Saccharomyces cerevisiae. , 2001, Genetics.

[15]  S. Elledge,et al.  The DNA damage response: putting checkpoints in perspective , 2000, Nature.

[16]  S. Jackson,et al.  LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae , 2000, The EMBO journal.

[17]  P. Plevani,et al.  Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1‐dependent pathway and Cdk1 activity , 2000, The EMBO journal.

[18]  G. Lucchini,et al.  The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. , 2000, Genes & development.

[19]  J. Haber,et al.  DNA Length Dependence of the Single-Strand Annealing Pathway and the Role of Saccharomyces cerevisiae RAD59 in Double-Strand Break Repair , 2000, Molecular and Cellular Biology.

[20]  P. Russell,et al.  Mechanism of Caffeine-Induced Checkpoint Override in Fission Yeast , 2000, Molecular and Cellular Biology.

[21]  F. Fabre,et al.  Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases , 2000, Nature Genetics.

[22]  C. Smythe,et al.  ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK , 1999, Oncogene.

[23]  P. Plevani,et al.  Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase , 1999, The EMBO journal.

[24]  H. Wang,et al.  Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms. , 1999, Science.

[25]  J. Mccusker,et al.  Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae , 1999, Yeast.

[26]  M. Yanagida,et al.  Cdc2 phosphorylation of Crb2 is required for reestablishing cell cycle progression after the damage checkpoint. , 1999, Molecular cell.

[27]  T. Weinert,et al.  RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast , 1999, The EMBO journal.

[28]  J. Haber,et al.  Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae , 1999, Microbiology and Molecular Biology Reviews.

[29]  J. Haber,et al.  Physical monitoring of HO-induced homologous recombination. , 1999, Methods in molecular biology.

[30]  D. Glover,et al.  Polo-like kinases: a team that plays throughout mitosis. , 1998, Genes & development.

[31]  Liang Cheng,et al.  Cell Cycle Regulation of the Saccharomyces cerevisiae Polo-Like Kinase Cdc5p , 1998, Molecular and Cellular Biology.

[32]  J. Haber,et al.  Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. , 1998, Genetics.

[33]  S. McCready,et al.  Differential effects of caffeine on DNA damage and replication cell cycle checkpoints in the fission yeast Schizosaccharomyces pombe , 1998, Molecular and General Genetics MGG.

[34]  T. Weinert.  DNA Damage and Checkpoint Pathways Molecular Anatomy and Interactions with Repair , 1998, Cell.

[35]  R Rothstein,et al.  A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools. , 1998, Molecular cell.

[36]  J. Haber,et al.  Saccharomyces Ku70, Mre11/Rad50, and RPA Proteins Regulate Adaptation to G2/M Arrest after DNA Damage , 1998, Cell.

[37]  M. A. de la Torre-Ruiz,et al.  RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation , 1998, The EMBO journal.

[38]  J. Haber,et al.  Expansions and Contractions in a Tandem Repeat Induced by Double-Strand Break Repair , 1998, Molecular and Cellular Biology.

[39]  Kim Nasmyth,et al.  The Polo‐like kinase Cdc5p and the WD‐repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae , 1998, The EMBO journal.

[40]  J. Haber,et al.  Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae , 1997, Molecular and cellular biology.

[41]  L. Hartwell,et al.  CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint , 1997, Cell.

[42]  J. Haber,et al.  Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[43]  T. Matsumoto.  A fission yeast homolog of CDC20/p55CDC/Fizzy is required for recovery from DNA damage and genetically interacts with p34cdc2 , 1997, Molecular and cellular biology.

[44]  Stephen J. Elledge,et al.  Cell Cycle Checkpoints: Preventing an Identity Crisis , 1996, Science.

[45]  J. Haber,et al.  Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae. , 1996, Genetics.

[46]  D. Stern,et al.  Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways. , 1996, Genes & development.

[47]  S. Elledge,et al.  Regulation of RAD53 by the ATM-Like Kinases MEC1 and TEL1 in Yeast Cell Cycle Checkpoint Pathways , 1996, Science.

[48]  L. Hartwell,et al.  Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint , 1995, Molecular and cellular biology.

[49]  J. Haber.  In vivo biochemistry: Physical monitoring of recombination induced by site‐specific endonucleases , 1995, BioEssays : news and reviews in molecular, cellular and developmental biology.

[50]  P. Philippsen,et al.  New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae , 1994, Yeast.

[51]  A. Murray,et al.  Cell Cycle Checkpoints , 2021, Encyclopedia of Molecular Pharmacology.

[52]  L. Hartwell,et al.  Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. , 1994, Genes & development.

[53]  Virginia A. Zakian,et al.  Loss of a yeast telomere: Arrest, recovery, and chromosome loss , 1993, Cell.

[54]  R. Chanet,et al.  Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins , 1992, Molecular and cellular biology.

[55]  J. Haber,et al.  Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated , 1992, Molecular and cellular biology.

[56]  J. Haber,et al.  Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation , 1992, Molecular and cellular biology.

[57]  R. Schiestl,et al.  The SRS2 suppressor of rad6 mutations of Saccharomyces cerevisiae acts by channeling DNA lesions into the RAD52 DNA repair pathway. , 1990, Genetics.

[58]  J. Haber,et al.  Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. , 1990, The EMBO journal.

[59]  R. Chanet,et al.  RADH, a gene of Saccharomyces cerevisiae encoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene. , 1989, Nucleic acids research.

[60]  L. Hartwell,et al.  The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. , 1988, Science.

[61]  R. Schlegel,et al.  Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells. , 1986, Science.

[62]  G. Church,et al.  Genomic sequencing. , 1993, Methods in molecular biology.

[63]  K. Volź,et al.  Radiation Response of Mammalian Cells Grown in Culture. IV. Dose Dependence of Division Delay and Postirradiation Growth of Surviving and Nonsurviving Chinese Hamster Cells , 1963 .

[64]  T. Puck,et al.  Action of radiation on mammalian cells. IV. Reversible mitotic lag in the S3 HeLa cell produced by low doses of x-rays. , 1961, Proceedings of the National Academy of Sciences of the United States of America.

[65]  V. W. Burns.  X-ray-induced division delay of individual yeast cells. , 1956, Radiation research.