Development of a Wireless Sensor for the Measurement of Chicken Blood Flow Using the Laser Doppler Blood Flow Meter Technique

Here, we report the development of an integrated laser Doppler blood flow micrometer for chickens. This sensor weighs only 18 g and is one of the smallest-sized blood flow meters, with no wired line, these are features necessary for attaching the sensor to the chicken. The structure of the sensor chip consists of two silicon cavities with a photo diode and a laser diode, which was achieved using the microelectromechanical systems technique, resulting in its small size and significantly low power consumption. In addition, we introduced an intermittent measuring arrangement in the measuring system to reduce power consumption and to enable the sensor to work longer. We were successfully able to measure chicken blood flow for five consecutive days, and discovered that chicken blood flow shows daily fluctuations.

[1]  R. Sawada,et al.  Low-power consumption integrated laser Doppler blood flowmeter with a built-in silicon microlens , 2008, 2008 IEEE/LEOS International Conference on Optical MEMs and Nanophotonics.

[2]  Yuichi Tanabe,et al.  Effects of different photoperiods on plasma melatonin rhythm of the chicken , 1995 .

[3]  N. Cox,et al.  Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. , 1998, Science.

[4]  David E. Swayne,et al.  Comparisons of Highly Virulent H5N1 Influenza A Viruses Isolated from Humans and Chickens from Hong Kong , 1998, Journal of Virology.

[5]  R. Anderson,et al.  The optics of human skin. , 1981, The Journal of investigative dermatology.

[6]  Thomas H. Haugen,et al.  Upstream Regulatory Region Alterations Found in Human Papillomavirus Type 16 (HPV-16) Isolates from Cervical Carcinomas Increase Transcription, ori Function, and HPV Immortalization Capacity in Culture , 2009, Journal of Virology.

[7]  Prasert Auewarakul,et al.  Probable person-to-person transmission of avian influenza A (H5N1). , 2005, The New England journal of medicine.

[8]  J. Farrar,et al.  Fatal avian influenza A (H5N1) in a child presenting with diarrhea followed by coma. , 2005, The New England journal of medicine.

[9]  Hironao Okada,et al.  Association of Increased Pathogenicity of Asian H5N1 Highly Pathogenic Avian Influenza Viruses in Chickens with Highly Efficient Viral Replication Accompanied by Early Destruction of Innate Immune Responses , 2009, Journal of Virology.

[10]  Hirofumi Nogami,et al.  Use of a simple arm-raising test with a portable laser Doppler blood flow meter to detect dehydration , 2011 .

[11]  Masaki Shuzo,et al.  New healthcare society supported by wearable sensors and information mapping-based services , 2011, Int. J. Netw. Virtual Organisations.

[12]  Wiendelt Steenbergen,et al.  Influence of optical properties and fiber separation on laser doppler flowmetry. , 2002, Journal of biomedical optics.

[13]  V. Rajan,et al.  Review of methodological developments in laser Doppler flowmetry , 2009, Lasers in Medical Science.

[14]  Renshi Sawada,et al.  Integrated Laser Doppler Blood Flowmeter Designed to Enable Wafer-Level Packaging , 2010, IEEE Transactions on Biomedical Engineering.

[15]  R. Nossal,et al.  Model for laser Doppler measurements of blood flow in tissue. , 1981, Applied optics.

[16]  Y. Guan,et al.  Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong SAR , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[17]  Wiendelt Steenbergen,et al.  Integrated Optoelectronic Probe Including a Vertical Cavity Surface Emitting Laser for Laser Doppler Perfusion Monitoring , 2006, IEEE Transactions on Biomedical Engineering.

[18]  Renshi Sawada,et al.  An integrated laser blood flowmeter , 2003 .

[19]  K. Itao.  Wearable Sensor Network Connecting Artifacts, Nature and Human Being , 2007, 2007 IEEE Sensors.

[20]  K. Urabe,et al.  Assessment of abnormal blood flow and efficacy of treatment in patients with systemic sclerosis using a newly developed microwireless laser Doppler flowmeter and arm‐raising test , 2007, The British journal of dermatology.

[21]  Hironao Okada,et al.  Wireless sensor system for detection of avian influenza outbreak farms at an early stage , 2009, 2009 IEEE Sensors.

[22]  H. Okada,et al.  Development of Low Power Technologies for Health Monitoring System Using Wireless Sensor Nodes , 2012, 2012 Second Workshop on Design, Control and Software Implementation for Distributed MEMS.

[23]  A. Lymberis,et al.  Advanced Wearable Health Systems and Applications - Research and Development Efforts in the European Union , 2007, IEEE Engineering in Medicine and Biology Magazine.

[24]  P. Daszak,et al.  Predicting the global spread of H5N1 avian influenza , 2006, Proceedings of the National Academy of Sciences.

[25]  Constance Schultsz,et al.  Avian influenza A (H5N1) in 10 patients in Vietnam. , 2004, The New England journal of medicine.

[26]  Hirofumi Nogami,et al.  Useful method to monitor the physiological effects of alcohol ingestion by combination of micro-integrated laser Doppler blood flow meter and arm-raising test , 2012, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[27]  Hironao Okada,et al.  Simulation study on the wireless sensor-based monitoring system for rapid identification of avian influenza outbreaks at chicken farms , 2010, 2010 IEEE Sensors.

[28]  Y. Guan,et al.  Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia , 2004, Nature.