Alteration of posture-related cortical potentials in mild traumatic brain injury

This paper presents additional evidence showing the persistent functional deficits in concussed athletes as revealed by altered movement-related cortical potentials (MRCP) preceding whole body postural movements at least 30 days post-injury. Eight student-athletes participated in this study (a) prior to injury; and (b) 3, 10 and 30 days after MTBI. EEG was recorded while subjects produced static balance tasks and dynamic postural movements. All subjects were cleared for sport participation within 10 days post-injury based upon neurological and neuropsychological assessments as well as upon clinical symptoms resolution. There was a persistent reduction of MRCP amplitude prior to initiation of postural movement up to 30 days post-injury, although abnormal postural responses basically recovered within 10 days post-injury. The frontal lobe MRCP effects were larger than posterior areas. This supports the notion that behavioral symptoms resolution may not be indicative of brain injury resolution. Overall, persistent alteration of movement-related cortical potentials after MTBI may indicate residual disturbance of neuronal networks involved in preparation and execution of postural movements and a lower threshold for brain re/injury.

[1]  W. Mccallum.  Human slow potential research: a review. , 1993 .

[2]  Semyon Slobounov,et al.  EEG and postural correlates of mild traumatic brain injury in athletes , 2005, Neuroscience Letters.

[3]  K. Newell,et al.  Aging and time to instability in posture. , 1998, The journals of gerontology. Series A, Biological sciences and medical sciences.

[4]  S. H. Curry,et al.  Slow Potential Changes in the Human Brain , 1993, NATO ASI Series.

[5]  L. Arendt-Nielsen,et al.  Quantitative posturography in altered sensory conditions: a way to assess balance instability in patients with chronic whiplash injury. , 2004, Archives of physical medicine and rehabilitation.

[6]  S. Slobounov,et al.  Neurophysiological and behavioral concomitants of mild brain injury in collegiate athletes , 2002, Clinical Neurophysiology.

[7]  M. Hallett,et al.  Role of cerebral cortex in human postural control: an EEG study , 2005, Clinical Neurophysiology.

[8]  D. Stuss,et al.  Principles of frontal lobe function , 2002 .

[9]  J. Doyle,et al.  Electroencephalogram correlates of higher cortical functions. , 1979, Science.

[10]  Karl M. Newell,et al.  Perceived effort in force production as reflected in motor-related cortical potentials , 2004, Clinical Neurophysiology.

[11]  William J. Ray,et al.  Movement-related potentials with reference to isometric force output in discrete and repetitive tasks , 1998, Experimental Brain Research.

[12]  L. Deecke,et al.  Movement-related potentials accompanying unilateral and bilateral finger movements with different inertial loads. , 1990, Electroencephalography and clinical neurophysiology.

[13]  H. Diener,et al.  Impaired movement-related potentials in acute frontal traumatic brain injury , 2004, Clinical Neurophysiology.

[14]  Slow negative cortical potential preceding the onset of postural adjustment. , 1996, Electroencephalography and clinical neurophysiology.

[15]  Donna K. Broshek,et al.  Acceleration-Deceleration Sport-Related Concussion: The Gravity of It All. , 2001, Journal of athletic training.

[16]  D. Stuss,et al.  How Long Does It Take to Recover from a Mild Concussion? , 1988, Neurosurgery.

[17]  H. Jasper.  Report of the committee on methods of clinical examination in electroencephalography , 1958 .

[18]  S. Slobounov,et al.  EEG correlates of wrist kinematics as revealed by averaging techniques and Morlet wavelet transforms. , 2000, Motor control.

[19]  H. Kornhuber,et al.  Hirnpotentialänderungen bei Willkürbewegungen und passiven Bewegungen des Menschen: Bereitschaftspotential und reafferente Potentiale , 1965, Pflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere.

[20]  R. Thatcher,et al.  Estimation of the EEG power spectrum using MRI T 2 relaxation time in traumatic brain injury , 2001, Clinical Neurophysiology.

[21]  Alain Ptito,et al.  Functional abnormalities in symptomatic concussed athletes: an fMRI study , 2004, NeuroImage.

[22]  K. Guskiewicz.  Assessment of postural stability following sport-related concussion. , 2003, Current sports medicine reports.

[23]  D. Mclone,et al.  Factors Influencing Posttraumatic Seizures in Children , 1988, Neurosurgery.

[24]  V. Hömberg,et al.  Cerebral potentials during skilled slow positioning movements , 1981, Biological Psychology.

[25]  H Shibasaki,et al.  Components of the movement-related cortical potential and their scalp topography. , 1980, Electroencephalography and clinical neurophysiology.

[26]  H. Diener,et al.  Recovery of movement-related potentials in the temporal course after prefrontal traumatic brain injury: a follow-up study , 2004, Clinical Neurophysiology.

[27]  A. Geurts,et al.  Is postural control associated with mental functioning in the persistent postconcussion syndrome? , 1999, Archives of physical medicine and rehabilitation.