Neurosteroid pathway derangement in asphyctic infants treated with hypothermia: an untargeted metabolomic approach

[1]  E. Giller,et al.  Ganaxolone , 2011, Neurotherapeutics.

[2]  G. Giordano,et al.  Urinary metabotypes of newborns with perinatal asphyxia undergoing therapeutic hypothermia , 2022, PloS one.

[3]  A. Dessì,et al.  NMR Metabonomic Profile of Preterm Human Milk in the First Month of Lactation: From Extreme to Moderate Prematurity , 2022, Foods.

[4]  Bruno Scarpa,et al.  PLS for classification , 2021 .

[5]  M. Longo,et al.  Ischemic hypoxic encephalopathy: The role of MRI of neonatal injury and medico-legal implication. , 2021, Forensic science international.

[6]  F. Piersigilli,et al.  A Metabolomic Approach in Search of Neurobiomarkers of Perinatal Asphyxia: A Review of the Current Literature , 2021, Frontiers in Pediatrics.

[7]  D. Sharkey,et al.  Outcomes of neonatal hypoxic-ischaemic encephalopathy in centres with and without active therapeutic hypothermia: a nationwide propensity score-matched analysis , 2021, Archives of Disease in Childhood.

[8]  W. Carlo,et al.  Early Determination of Prognosis in Neonatal Moderate or Severe Hypoxic-Ischemic Encephalopathy , 2021, Pediatrics.

[9]  José David Piñeiro-Ramos,et al.  Noninvasive monitoring of evolving urinary metabolic patterns in neonatal encephalopathy , 2021, Pediatric Research.

[10]  C. Giaquinto,et al.  Untargeted and Targeted Metabolomic Profiling of Preterm Newborns with EarlyOnset Sepsis: A Case-Control Study , 2021, Metabolites.

[11]  H. Arai,et al.  Functional outcomes of children with dyskinetic cerebral palsy depend on etiology and gestational age. , 2020, European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.

[12]  E. d’Aloja,et al.  Exploring Perinatal Asphyxia by Metabolomics , 2020, Metabolites.

[13]  José David Piñeiro-Ramos,et al.  Metabolic Phenotypes of Hypoxic-Ischemic Encephalopathy with Normal vs. Pathologic Magnetic Resonance Imaging Outcomes , 2020, Metabolites.

[14]  José David Piñeiro-Ramos,et al.  Small molecule biomarkers for neonatal hypoxic ischemic encephalopathy. , 2020, Seminars in fetal & neonatal medicine.

[15]  G. Boylan,et al.  Two-Year Neurodevelopmental Outcomes After Mild Hypoxic Ischemic Encephalopathy in the Era of Therapeutic Hypothermia. , 2019, JAMA pediatrics.

[16]  Shaun Wen Huey Lee,et al.  Comparative Efficacy and Safety of Neuroprotective Therapies for Neonates With Hypoxic Ischemic Encephalopathy: A Network Meta-Analysis , 2019, Front. Pharmacol..

[17]  V. Lazarenko,et al.  L-Lysine as the Molecule Influencing Selective Brain Activity in Pain-Induced Behavior of Rats , 2019, International journal of molecular sciences.

[18]  E. d’Aloja,et al.  A longitudinal 1H-NMR metabolomics analysis of urine from newborns with hypoxic-ischemic encephalopathy undergoing hypothermia therapy. Clinical and medical legal insights , 2018, PloS one.

[19]  T. Atey,et al.  Neuroactive Steroids: Receptor Interactions and Responses , 2017, Front. Neurol..

[20]  L. Bennet,et al.  Ganaxolone: A New Treatment for Neonatal Seizures , 2017, Front. Cell. Neurosci..

[21]  L. Barberini,et al.  Urinary gas chromatography mass spectrometry metabolomics in asphyxiated newborns undergoing hypothermia: from the birth to the first month of life. , 2016, Annals of translational medicine.

[22]  J. Perlman,et al.  Pathophysiology of Birth Asphyxia. , 2016, Clinics in perinatology.

[23]  J. Kuligowski,et al.  Changes of the plasma metabolome of newly born piglets subjected to postnatal hypoxia and resuscitation with air , 2016, Pediatric Research.

[24]  G. Boylan,et al.  Short and long term prognosis in perinatal asphyxia: An update. , 2016, World journal of clinical pediatrics.

[25]  E. Cone,et al.  Metabolism and Disposition of Prescription Opioids: A Review. , 2015, Forensic science review.

[26]  G. Buonocore,et al.  Proton nuclear magnetic resonance spectroscopy of urine samples in preterm asphyctic newborn: a metabolomic approach. , 2015, Clinica chimica acta; international journal of clinical chemistry.

[27]  Anthony P. King,et al.  Allopregnanolone Elevations Following Pregnenolone Administration Are Associated with Enhanced Activation of Emotion Regulation Neurocircuits , 2013, Biological Psychiatry.

[28]  P. Davis,et al.  Cooling for newborns with hypoxic ischaemic encephalopathy. , 2013, The Cochrane database of systematic reviews.

[29]  M. Carta,et al.  GABAergic neuroactive steroids: a new frontier in bipolar disorders? , 2012, Behavioral and Brain Functions.

[30]  M. Kavanaugh,et al.  Oxygen Glucose Deprivation in Rat Hippocampal Slice Cultures Results in Alterations in Carnitine Homeostasis and Mitochondrial Dysfunction , 2012, PloS one.

[31]  Marat Minlebaev,et al.  Newborn Analgesia Mediated by Oxytocin during Delivery , 2011, Front. Cell. Neurosci..

[32]  E. Yan,et al.  Neuroactive steroids induce changes in fetal sheep behavior during normoxic and asphyxic states , 2011, Stress.

[33]  T. Tomson,et al.  Progress report on new antiepileptic drugs: A summary of the Twelfth Eilat Conference (EILAT XII) , 2015, Epilepsy Research.

[34]  G. Simbruner,et al.  Systemic Hypothermia After Neonatal Encephalopathy: Outcomes of neo.nEURO.network RCT , 2010, Pediatrics.

[35]  L. Du,et al.  Selective head cooling with mild systemic hypothermia after neonatal hypoxic-ischemic encephalopathy: a multicenter randomized controlled trial in China. , 2010, The Journal of pediatrics.

[36]  M. Rogawski,et al.  Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model , 2010, Epilepsy Research.

[37]  T. Ono,et al.  Lysine and Arginine Reduce the Effects of Cerebral Ischemic Insults and Inhibit Glutamate-Induced Neuronal Activity in Rats , 2010, Front. Integr. Neurosci..

[38]  T. Koal,et al.  Metabolomic Analyses of Plasma Reveals New Insights into Asphyxia and Resuscitation in Pigs , 2010, PloS one.

[39]  N. Marlow,et al.  Moderate hypothermia to treat perinatal asphyxial encephalopathy. , 2009, The New England journal of medicine.

[40]  M. Taggart,et al.  Are animal models relevant to key aspects of human parturition? , 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

[41]  R. Irwin,et al.  Regenerative potential of allopregnanolone , 2008, Brain Research Reviews.

[42]  L. Garcia-Segura,et al.  Neuroactive steroids: State of the art and new perspectives , 2008, Cellular and Molecular Life Sciences.

[43]  M. Dutia,et al.  Neurosteroid modulation of neuronal excitability and synaptic transmission in the rat medial vestibular nuclei , 2007, The European journal of neuroscience.

[44]  D. Walker,et al.  Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep , 2007, Neuroscience.

[45]  R. Khazipov,et al.  Maternal Oxytocin Triggers a Transient Inhibitory Switch in GABA Signaling in the Fetal Brain During Delivery , 2006, Science.

[46]  C. Pang,et al.  Metabolomic and bioinformatic analyses in asphyxiated neonates. , 2006, Clinical biochemistry.

[47]  William Oh,et al.  Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. , 2005, The New England journal of medicine.

[48]  Andrew Whitelaw,et al.  Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial , 2005, The Lancet.

[49]  M. Schumacher,et al.  Systemic progesterone administration results in a partial reversal of the age‐associated decline in CNS remyelination following toxin‐induced demyelination in male rats , 2004, Neuropathology and applied neurobiology.

[50]  Y. Ben-Ari,et al.  Paracrine Intercellular Communication by a Ca2+- and SNARE-Independent Release of GABA and Glutamate Prior to Synapse Formation , 2002, Neuron.

[51]  G. Baker,et al.  Neuroactive steroids and anxiety disorders. , 2002, Journal of psychiatry & neuroscience : JPN.

[52]  A. Urani,et al.  The interaction between neuroactive steroids and the σ1 receptor function: behavioral consequences and therapeutic opportunities , 2001, Brain Research Reviews.

[53]  M. Rogawski,et al.  Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself. , 2000, The Journal of pharmacology and experimental therapeutics.

[54]  F. Holsboer,et al.  Functional antagonism of gonadal steroids at the 5-hydroxytryptamine type 3 receptor. , 1998, Molecular endocrinology.

[55]  J. A. Peters,et al.  Neurosteroids and GABAA receptor function. , 1995, Trends in pharmacological sciences.

[56]  D. Farb,et al.  3 alpha-Hydroxy-5 beta-pregnan-20-one sulfate: a negative modulator of the NMDA-induced current in cultured neurons. , 1994, Molecular pharmacology.

[57]  B. Wojtyniak,et al.  Perinatal mortality in Matlab, Bangladesh: a community-based study. , 1990, International journal of epidemiology.

[58]  R. B. Freas,et al.  Identification of metabolites of ampicillin using liquid chromatography/thermospray mass spectrometry and fast atom bombardment tandem mass spectrometry. , 1989, Biomedical & environmental mass spectrometry.

[59]  D. Wingate,et al.  PARACRINE , 1976, The Lancet.

[60]  Heng Tao Shen,et al.  Principal Component Analysis , 2009, Encyclopedia of Biometrics.

[61]  X. De Muylder.  Perinatal mortality audit in a Zimbabwean district. , 1989, Paediatric and perinatal epidemiology.