Maximal emission beyond 1200 nm dicyanovinyl-functionalized squaraine for in vivo vascular imaging.

The first maximum emission wavelength beyond 1200 nm acceptor-substituted squaraine fluorophore with ultra-high brightness and photostability has been developed. It can be co-assembled with bovine serum albumin to form an excellent biocompatible dye-protein nanocomplex with significant fluorescence enhancement for high-resolution vascular imaging.