Regulatory and immunopathological roles of IL4 in experimental schistosomiasis.

[1]  A. Sher,et al.  Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. , 1993, Journal of immunology.

[2]  J. Berzofsky,et al.  Fcϵ receptor‐positive cells are a major source of antigen‐induced interIeukin‐4 in spleens of mice infected with Schistosoma mansoni , 1993 .

[3]  W. Paul,et al.  Anti-IL-4 diminishes in vivo priming for antigen-specific IL-4 production by T cells. , 1993, Journal of immunology.

[4]  T. Yamashita,et al.  IL-4 influences IL-2 production and granulomatous inflammation in murine schistosomiasis mansoni. , 1992, Journal of immunology.

[5]  A. Sher,et al.  Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor alpha required as a costimulatory factor for interferon gamma-induced activation. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[6]  A. Sher,et al.  IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity. , 1992, Journal of immunology.

[7]  J. Berzofsky,et al.  Role of T‐Cell Derived Cytokines in the Downregulation of Immune Responses in Parasitic and Retroviral Infection , 1992, Immunological reviews.

[8]  C. Dinarello,et al.  Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[9]  E. Pearce,et al.  CD4+ Th2 response induced by Schistosoma mansoni eggs develops rapidly, through an early, transient, Th0-like stage. , 1992, Journal of immunology.

[10]  A. Sher,et al.  Production of IL-10 by CD4+ T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection. , 1991, Journal of immunology.

[11]  R. Coffman,et al.  Role of Cytokines in the Differentiation of CD4+ T‐Cell Subsets in vivo , 1991, Immunological reviews.

[12]  M. Meltzer,et al.  T-cell-mediated activation of macrophages. , 1991, Current opinion in immunology.

[13]  W. Paul Interleukin-4: a prototypic immunoregulatory lymphokine. , 1991, Blood.

[14]  W. Paul,et al.  Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[15]  A. Sher,et al.  Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni. , 1991, Journal of immunology.

[16]  A. Sher,et al.  Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni , 1991, The Journal of experimental medicine.

[17]  R. Coffman,et al.  Ablation of eosinophil and IgE responses with anti-IL-5 or anti-IL-4 antibodies fails to affect immunity against Schistosoma mansoni in the mouse. , 1990, Journal of immunology.

[18]  J. Hibbs,et al.  The role of nitrogen oxides as effector molecules of parasite killing. , 1990, Parasitology today.

[19]  S. Kaufmann,et al.  Activation of tuberculostatic macrophage functions by gamma interferon, interleukin-4, and tumor necrosis factor , 1990, Infection and immunity.

[20]  S. James,et al.  Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates. , 1989, Journal of immunology.

[21]  R. Coffman,et al.  Role of Cytokines and CD4+ T‐Cell Subsets in the Regulation of Parasite Immunity and Disease , 1989, Immunological reviews.

[22]  H. Remold,et al.  IL-4 inhibits H2O2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-gamma. , 1989, Journal of immunology.

[23]  C. Figdor,et al.  Modulation of phenotypic and functional properties of human peripheral blood monocytes by IL-4. , 1988, Journal of immunology.

[24]  D. Rennick,et al.  Interleukin 4 induces cultured monocytes/macrophages to form giant multinucleated cells , 1988, The Journal of experimental medicine.

[25]  A. Capron Immunity to schistosomes. , 1992 .

[26]  P. Basch Schistosomes : development, reproduction, and host relations , 1991 .

[27]  A. Sher,et al.  Cell-mediated immune response to schistosomiasis. , 1990, Current topics in microbiology and immunology.

[28]  R. Coffman,et al.  TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. , 1989, Annual review of immunology.