Inhalation threshold of toxicological concern (TTC) - Structural alerts discriminate high from low repeated-dose inhalation toxicity.
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[1] Andrew Worth,et al. Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision Making , 2015, Environmental health perspectives.
[2] G. Schüürmann,et al. Computational biotransformation profile of paracetamol catalyzed by cytochrome P450. , 2015, Chemical research in toxicology.
[3] Cathrine Thomsen,et al. Human exposure pathways to organophosphate triesters - a biomonitoring study of mother-child pairs. , 2015, Environment international.
[4] W. Völkel,et al. Organophosphate flame retardants and plasticizers in the air and dust in German daycare centers and human biomonitoring in visiting children (LUPE 3). , 2014, Environment international.
[5] Melvin E. Andersen,et al. Molecular Signaling Network Motifs Provide a Mechanistic Basis for Cellular Threshold Responses , 2014, Environmental health perspectives.
[6] D. Krewski,et al. A Framework for the Next Generation of Risk Science , 2014, Environmental health perspectives.
[7] N. Gharbi,et al. Bisphenol A and human chronic diseases: current evidences, possible mechanisms, and future perspectives. , 2014, Environment international.
[8] W. Dekant,et al. Mammalian toxicology and human exposures to the flame retardant 2,2′,6,6′-tetrabromo-4,4′-isopropylidenediphenol (TBBPA): implications for risk assessment , 2013, Archives of Toxicology.
[9] Courtney C. Carignan,et al. Predictors of tris(1,3-dichloro-2-propyl) phosphate metabolite in the urine of office workers. , 2013, Environment international.
[10] C. Ambrosino,et al. Bisphenol A interferes with thyroid specific gene expression. , 2013, Toxicology.
[11] Gerrit Schüürmann,et al. Model and mechanism: N-hydroxylation of primary aromatic amines by cytochrome P450. , 2013, Angewandte Chemie.
[12] E. C. Hennes,et al. An overview of values for the threshold of toxicological concern. , 2012, Toxicology letters.
[13] K. Main,et al. Thyroid effects of endocrine disrupting chemicals , 2012, Molecular and Cellular Endocrinology.
[14] Ben-Zhan Zhu,et al. Low concentrations of bisphenol a suppress thyroid hormone receptor transcription through a nongenomic mechanism. , 2012, Toxicology and applied pharmacology.
[15] C. Wild,et al. The exposome: from concept to utility. , 2012, International journal of epidemiology.
[16] Gerrit Schüürmann,et al. Computational evidence for α-nitrosamino radical as initial metabolite for both the P450 dealkylation and denitrosation of carcinogenic nitrosamines. , 2012, The journal of physical chemistry. B.
[17] S. Rappaport. Discovering environmental causes of disease , 2011, Journal of Epidemiology & Community Health.
[18] H. Buist,et al. Improvement of the Cramer classification for oral exposure using the database TTC RepDose--a strategy description. , 2011, Regulatory toxicology and pharmacology : RTP.
[19] Ralph Kühne,et al. Quantitative read-across for predicting the acute fish toxicity of organic compounds. , 2011, Environmental science & technology.
[20] S E Escher,et al. Evaluation of inhalation TTC values with the database RepDose. , 2010, Regulatory toxicology and pharmacology : RTP.
[21] Stephen M Rappaport,et al. Environment and Disease Risks , 2010, Science.
[22] Ralph Kühne,et al. Chemical Domain of QSAR Models from Atom-Centered Fragments , 2009, J. Chem. Inf. Model..
[23] Hong Sun,et al. Anti-thyroid hormone activity of bisphenol A, tetrabromobisphenol A and tetrachlorobisphenol A in an improved reporter gene assay. , 2009, Toxicology in vitro : an international journal published in association with BIBRA.
[24] T. Hartung. Toxicology for the twenty-first century , 2009, Nature.
[25] S. Gutsell,et al. Exposure based waiving: the application of the toxicological threshold of concern (TTC) to inhalation exposure for aerosol ingredients in consumer products. , 2009, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[26] G. Schüürmann,et al. External Validation and Prediction Employing the Predictive Squared Correlation Coefficient Test Set Activity Mean vs Training Set Activity Mean , 2008, J. Chem. Inf. Model..
[27] I C Munro,et al. The Threshold of Toxicological Concern (TTC) in risk assessment. , 2008, Toxicology letters.
[28] F. Collins,et al. Transforming Environmental Health Protection , 2008, Science.
[29] C. Wild. Complementing the Genome with an “Exposome”: The Outstanding Challenge of Environmental Exposure Measurement in Molecular Epidemiology , 2005, Cancer Epidemiology Biomarkers & Prevention.
[30] Jennifer A. Prescher,et al. Chemistry in living systems , 2005, Nature chemical biology.
[31] M. Iida,et al. Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis. , 2005, Life sciences.
[32] J. Kazius,et al. Derivation and validation of toxicophores for mutagenicity prediction. , 2005, Journal of medicinal chemistry.
[33] J. Bolton,et al. Role of quinones in toxicology. , 2000, Chemical research in toxicology.
[34] C. Russom,et al. Predicting modes of toxic action from chemical structure: Acute toxicity in the fathead minnow (Pimephales promelas) , 1997 .
[35] R A Ford,et al. Correlation of structural class with no-observed-effect levels: a proposal for establishing a threshold of concern. , 1996, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[36] Michael Schindler,et al. Fish Toxicity and Dealkylation of Aromatic Phosphorothionates ‐ QSAR∗ Analysis Using NMR Chemical Shifts Calculated by the IGLO Method , 1993 .
[37] I. Tinsley. Chemical Concepts in Pollutant Behavior , 1979 .
[38] M. Johnson,et al. Organophosphorus esters causing delayed neurotoxic effects , 1975, Archives of Toxicology.
[39] C. A. Hoppert,et al. Chronic toxicity studies. III. Chronic toxicity of cadmium and chromium in dogs. , 1961, Archives of environmental health.
[40] H. Kalkhof,et al. Threshold of toxicological concern values for non-genotoxic effects in industrial chemicals: re-evaluation of the Cramer classification , 2011, Archives of Toxicology.
[41] P. O'Brien. Molecular mechanisms of quinone cytotoxicity. , 1991, Chemico-biological interactions.
[42] E. Cadenas,et al. Redox and addition chemistry of quinoid compounds and its biological implications. , 1989, Free radical biology & medicine.
[43] R A Ford,et al. Estimation of toxic hazard--a decision tree approach. , 1978, Food and cosmetics toxicology.
[44] R. J. Kuhr,et al. Carbamate insecticides: chemistry, biochemistry, and toxicology. , 1976 .
[45] W. R. Day. ENVIRONMENT AND DISEASE A Discussion on the Parasitism of Armillaria mellea Vahl. Fr. , 1929 .