Stat3 is required for full neoplastic transformation by the Simian Virus 40 large tumor antigen.
暂无分享,去创建一个
J. Turkson | R. Jove | G. Niu | A. Vultur | L. Raptis | R. Arulanandam
[1] A. Vultur,et al. Transfection techniques affecting Stat3 activity levels. , 2005, Analytical biochemistry.
[2] D. Kaplan,et al. SRC regulates actin dynamics and invasion of malignant glial cells in three dimensions. , 2004, Molecular cancer research : MCR.
[3] C. Daniels,et al. Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis. , 2004, The Journal of clinical investigation.
[4] J. Turkson,et al. Cell-to-cell adhesion modulates Stat3 activity in normal and breast carcinoma cells , 2004, Oncogene.
[5] J. Turkson,et al. Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity. , 2004, Molecular cancer therapeutics.
[6] Hua Yu,et al. The STATs of cancer — new molecular targets come of age , 2004, Nature Reviews Cancer.
[7] M. Schaller,et al. FAK regulates biological processes important for the pathogenesis of cancer , 2003, Cancer and Metastasis Reviews.
[8] Rakesh Nagarajan,et al. Mechanisms of transcriptional regulation by Rb-E2F segregate by biological pathway , 2003, Oncogene.
[9] E. Surmacz,et al. Role of the IGF‐I receptor in the regulation of cell–cell adhesion: Implications in cancer development and progression , 2003, Journal of cellular physiology.
[10] Jean Y. J. Wang,et al. Coordinated regulation of life and death by RB , 2003, Nature Reviews Cancer.
[11] Hua Yu,et al. Inhibition of Bcr–Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells , 2002, Oncogene.
[12] R. Jove,et al. Molecular characterization and sensitivity of STI-571 (imatinib mesylate, Gleevec)-resistant, Bcr-Abl-positive, human acute leukemia cells to SRC kinase inhibitor PD180970 and 17-allylamino-17-demethoxygeldanamycin. , 2002, Cancer research.
[13] B. Rothen‐Rutishauser,et al. Dynamics of Tight and Adherens Junctions Under EGTA Treatment , 2002, The Journal of Membrane Biology.
[14] J. Pipas,et al. T Antigens of Simian Virus 40: Molecular Chaperones for Viral Replication and Tumorigenesis , 2002, Microbiology and Molecular Biology Reviews.
[15] Jiayuh Lin,et al. p53 regulates Stat3 phosphorylation and DNA binding activity in human prostate cancer cells expressing constitutively active Stat3 , 2002, Oncogene.
[16] Rosalie C Sears,et al. Signaling Networks That Link Cell Proliferation and Cell Fate* , 2002, The Journal of Biological Chemistry.
[17] P. Greer. Closing in on the biological functions of fps/fes and fer , 2002, Nature Reviews Molecular Cell Biology.
[18] C. Ramana,et al. The Role of Hsp90N, a New Member of the Hsp90 Family, in Signal Transduction and Neoplastic Transformation* , 2002, The Journal of Biological Chemistry.
[19] Jiayuh Lin,et al. Modulation of signal transducer and activator of transcription 3 activities by p53 tumor suppressor in breast cancer cells. , 2002, Cancer research.
[20] J. Turkson,et al. Phosphotyrosyl Peptides Block Stat3-mediated DNA Binding Activity, Gene Regulation, and Cell Transformation* , 2001, The Journal of Biological Chemistry.
[21] J. Miyazaki,et al. Tissue-Specific Autoregulation of thestat3 Gene and Its Role in Interleukin-6-Induced Survival Signals in T Cells , 2001, Molecular and Cellular Biology.
[22] T. Roberts,et al. Simian Virus 40 Large Tumor Antigen Modulates the Raf Signaling Pathway* , 2001, The Journal of Biological Chemistry.
[23] Hua Yu,et al. Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells , 2001, Oncogene.
[24] B. Elliott,et al. Co-operative Effect of c-Src Tyrosine Kinase and Stat3 in Activation of Hepatocyte Growth Factor Expression in Mammary Carcinoma Cells* , 2001, The Journal of Biological Chemistry.
[25] N. Dyson,et al. p107 and p130: versatile proteins with interesting pockets. , 2001, Experimental cell research.
[26] D. Link,et al. STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation. , 2001, Immunity.
[27] J. Turkson,et al. Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. , 2001, The Journal of clinical investigation.
[28] T. Jacks,et al. Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. , 2000, Genes & development.
[29] J. Turkson,et al. Activation of Stat3 in v-Src-transformed Fibroblasts Requires Cooperation of Jak1 Kinase Activity* , 2000, The Journal of Biological Chemistry.
[30] S. Akira. Roles of STAT3 defined by tissue-specific gene targeting , 2000, Oncogene.
[31] R. Jove,et al. Activation of Stat3 preassembled with platelet-derived growth factor β receptors requires Src kinase activity , 2000, Oncogene.
[32] Simon C Watkins,et al. Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[33] J. Darnell,et al. Stat3 as an Oncogene , 1999, Cell.
[34] Monilola A. Olayioye,et al. ErbB Receptor-induced Activation of Stat Transcription Factors Is Mediated by Src Tyrosine Kinases* , 1999, The Journal of Biological Chemistry.
[35] M. Vignais,et al. Distinct Mechanisms of Activation of Stat1 and Stat3 by Platelet-Derived Growth Factor Receptor in a Cell-Free System , 1999, Molecular and Cellular Biology.
[36] J. Turkson,et al. Stat3 Activation by Src Induces Specific Gene Regulation and Is Required for Cell Transformation , 1998, Molecular and Cellular Biology.
[37] J. Darnell,et al. Stat3 Activation Is Required for Cellular Transformation by v-src , 1998, Molecular and Cellular Biology.
[38] J. Decaprio,et al. The J Domain of Simian Virus 40 Large T Antigen Is Required To Functionally Inactivate RB Family Proteins , 1998, Molecular and Cellular Biology.
[39] G. Ramponi,et al. c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells. , 1997, Biochemical and biophysical research communications.
[40] S. Hanks,et al. Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src. , 1996, Biochemical and biophysical research communications.
[41] M. Vignais,et al. Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins , 1996, Molecular and cellular biology.
[42] R. Baserga,et al. Association of insulin receptor substrate 1 with simian virus 40 large T antigen , 1995, Molecular and cellular biology.
[43] R. Jove,et al. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. , 1995, Science.
[44] J. Swantek,et al. An E2F binding sequence negatively regulates the response of the insulin-like growth factor 1 (IGF-I) promoter to simian virus 40T antigen and to serum. , 1994, Oncogene.
[45] J. Johnston,et al. Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2 , 1994, Nature.
[46] E. Liu,et al. Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells , 1994, Nature.
[47] D. Coppola,et al. Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts , 1994, Molecular and cellular biology.
[48] D. Tedesco,et al. Limits of transforming competence of SV40 nuclear and cytoplasmic large T mutants with altered Rb binding sequences. , 1993, Oncogene.
[49] T. Yamamoto,et al. CSK: a protein-tyrosine kinase involved in regulation of src family kinases. , 1991, The Journal of biological chemistry.
[50] B. Cochran,et al. The SIF binding element confers sis/PDGF inducibility onto the c‐fos promoter. , 1990, The EMBO journal.
[51] F. Ciardiello,et al. Differential growth factor expression in transformed mouse NIH‐3T3 cells , 1990, Journal of cellular biochemistry.
[52] F. Traganos,et al. Growth of immortal simian virus 40 tsA-transformed human fibroblasts is temperature dependent , 1989, Molecular and cellular biology.
[53] L. Raptis,et al. Regulation of cellular phenotype and expression of polyomavirus middle T antigen in rat fibroblasts , 1985, Molecular and cellular biology.
[54] B. Ozanne,et al. Polyoma virus-transformed cells produce transforming growth factor(s) and grow in serum-free medium. , 1982, Virology.
[55] Jeffrey M. Trimarchi,et al. Transcription: Sibling rivalry in the E2F family , 2002, Nature Reviews Molecular Cell Biology.
[56] D. Levy,et al. Signalling: STATs: transcriptional control and biological impact , 2002, Nature Reviews Molecular Cell Biology.
[57] J. Turkson,et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. , 1999, Immunity.
[58] K. Kinzler,et al. A simplified system for generating recombinant adenoviruses. , 1998, Proceedings of the National Academy of Sciences of the United States of America.