Mechanical Properties and Corrosion Resistance of Magnesium–Hydroxyapatite Composites Fabricated by Spark Plasma Sintering

Recent studies indicate that biodegradable magnesium alloys and composites are attracting a great deal of attention in orthopedic applications. In this study, magnesium–hydroxyapatite (Mg–HAP) composites with different compositions and grain size were fabricated by a spark plasma sintering (SPS) method. Their mechanical properties and corrosion behavior in a pseudo-physiological environment were investigated by pH measurements and inductivity coupled plasma (ICP) elemental analysis after an immersion test using Hanks’ solution. The results clearly showed that the addition of HAP improved both the mechanical properties and corrosion resistance. The results also indicated that the finer grain size improved most of the properties that are needed in a material for an orthopedic implant. Furthermore, the authors reveal that there is a strong correlation between the compressive strength and the porosity. In order to achieve the same compressive strength as human bone using these fabrication conditions, it is revealed that the porosity should be lower than 1.9%.

[1]  A. Shanaghi,et al.  Investigation on the corrosion behavior and biocompatibility of Ti-6Al-4V implant coated with HA/TiN dual layer for medical applications , 2020 .

[2]  R. B. Soares,et al.  Corrosion Behavior in Hank's Solution of a Magnesium–Hydroxyapatite Composite Processed by High‐Pressure Torsion , 2020, Advanced Engineering Materials.

[3]  J. Teng,et al.  Corrosion-wear behavior of a biocompatible magnesium matrix composite in simulated body fluid , 2020, Friction.

[4]  D. Vojtěch,et al.  Characterization of Newly Developed Zinc Composite with the Content of 8 wt.% of Hydroxyapatite Particles Processed by Extrusion , 2020, Materials.

[5]  J. Kubásek,et al.  Characterization of a Zn-Ca5(PO4)3(OH) Composite with a High Content of the Hydroxyapatite Particles Prepared by the Spark Plasma Sintering Process , 2020 .

[6]  S. Iyengar,et al.  Magnesium/Nano-hydroxyapatite Composite for Bone Reconstruction: The Effect of Processing Method , 2020 .

[7]  S. Hiromoto,et al.  In Vitro Corrosion and Cell Response of Hydroxyapatite Coated Mg Matrix in Situ Composites for Biodegradable Material Applications , 2019, Materials.

[8]  Sachiko Hiromoto,et al.  In Vitro Corrosion Properties of Mg Matrix In Situ Composites Fabricated by Spark Plasma Sintering , 2017 .

[9]  Kateryna Bazaka,et al.  Metallic Biomaterials: Current Challenges and Opportunities , 2017, Materials.

[10]  Jun Ma,et al.  Fabrication, characterization, and in vitro study of zinc substituted hydroxyapatite/silk fibroin composite coatings on titanium for biomedical applications , 2017, Journal of biomaterials applications.

[11]  M. A. Rodríguez,et al.  Calcium phosphates for biomedical applications , 2017 .

[12]  James F Curtin,et al.  Biodegradable magnesium alloys for orthopaedic applications: A review on corrosion, biocompatibility and surface modifications. , 2016, Materials science & engineering. C, Materials for biological applications.

[13]  Tatsuo Sato,et al.  Sintering Behavior and Mechanical Properties of Magnesium/β-Tricalcium Phosphate Composites Sintered by Spark Plasma Sintering , 2016 .

[14]  J. Kubásek,et al.  The effect of hydroxyapatite reinforcement and preparation methods on the structure and mechanical properties of Mg-HA composites , 2017 .

[15]  Yasuhiro Tanimoto,et al.  A review of improved fixation methods for dental implants. Part II: biomechanical integrity at bone-implant interface. , 2015, Journal of prosthodontic research.

[16]  Jow-Lay Huang,et al.  Strengthening alumina ceramic matrix nanocomposites using spark plasma sintering , 2014 .

[17]  A. Demir,et al.  The processing of ultrafine-grained Mg tubes for biodegradable stents. , 2013, Acta biomaterialia.

[18]  R. Mishra,et al.  Effects of grain size on the corrosion resistance of wrought magnesium alloys containing neodymium , 2012 .

[19]  M. Ketteler,et al.  Magnesium basics , 2012, Clinical kidney journal.

[20]  I. Onche,et al.  Removal of orthopaedic implants: indications, outcome and economic implications. , 2011, Journal of the West African College of Surgeons.

[21]  M. Escudero,et al.  Corrosion behaviour of AZ31 magnesium alloy with different grain sizes in simulated biological fluids. , 2010, Acta biomaterialia.

[22]  Zhigang Xu,et al.  Preparation and Characterization of Porous Magnesium Alloys in Biomedical Applications , 2009 .

[23]  B. Hanson,et al.  Surgeons' beliefs and perceptions about removal of orthopaedic implants , 2008, BMC musculoskeletal disorders.

[24]  Alexis M Pietak,et al.  Magnesium and its alloys as orthopedic biomaterials: a review. , 2006, Biomaterials.

[25]  Z. A. Munir,et al.  The effect of electric field and pressure on the synthesis and consolidation of materials: A review of the spark plasma sintering method , 2006 .

[26]  C. R. Howlett,et al.  Mechanisms of magnesium-stimulated adhesion of osteoblastic cells to commonly used orthopaedic implants. , 2002, Journal of biomedical materials research.

[27]  Ö. Morgül,et al.  Friction and wear behaviour of implanted AISI 316L SS and comparison with a substrate , 2002 .

[28]  T. Aizawa,et al.  Precipitation of magnesium apatite on pure magnesium surface during immersing in Hank's solution , 2001 .

[29]  S. Radin,et al.  Microstructure and fretting behavior of hard TiN-based coatings on surgical titanium alloys , 2000 .

[30]  J. Langford,et al.  Scherrer after sixty years: a survey and some new results in the determination of crystallite size , 1978 .

[31]  P. Scherrer Bestimmung der inneren Struktur und der Größe von Kolloidteilchen mittels Röntgenstrahlen , 1912 .