The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin

[1]  L. del Peso,et al.  The von Hippel Lindau/Hypoxia-inducible Factor (HIF) Pathway Regulates the Transcription of the HIF-Proline Hydroxylase Genes in Response to Low Oxygen* , 2003, Journal of Biological Chemistry.

[2]  J. Pouysségur,et al.  HIF prolyl‐hydroxylase 2 is the key oxygen sensor setting low steady‐state levels of HIF‐1α in normoxia , 2003, The EMBO journal.

[3]  K. Kivirikko,et al.  Characterization of the Human Prolyl 4-Hydroxylases That Modify the Hypoxia-inducible Factor* , 2003, Journal of Biological Chemistry.

[4]  P. Ratcliffe,et al.  HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O2 levels , 2003, Journal of Cell Science.

[5]  J. Frydman,et al.  The Hsp70 and TRiC/CCT Chaperone Systems Cooperate In Vivo To Assemble the Von Hippel-Lindau Tumor Suppressor Complex , 2003, Molecular and Cellular Biology.

[6]  B. Bowen,et al.  Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells. , 2003, Biochemical and biophysical research communications.

[7]  W. Jelkmann,et al.  Intracellular localisation of human HIF-1α hydroxylases: implications for oxygen sensing , 2003, Journal of Cell Science.

[8]  M. Guenther,et al.  Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex. , 2002, Genes & development.

[9]  Jianhe Huang,et al.  Sequence Determinants in Hypoxia-inducible Factor-1α for Hydroxylation by the Prolyl Hydroxylases PHD1, PHD2, and PHD3* , 2002, The Journal of Biological Chemistry.

[10]  Matthias Schramm,et al.  Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors. , 2002, Biochemical and biophysical research communications.

[11]  K. Resing,et al.  Regulatory interaction of phosducin-like protein with the cytosolic chaperonin complex , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[12]  F. Hartl,et al.  Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein , 2002, Science.

[13]  W. Kaelin,et al.  Diverse Effects of Mutations in Exon II of the von Hippel-Lindau (VHL) Tumor Suppressor Gene on the Interaction of pVHL with the Cytosolic Chaperonin and pVHL-Dependent Ubiquitin Ligase Activity , 2002, Molecular and Cellular Biology.

[14]  K. Polyak,et al.  Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression) , 2002, Oncogene.

[15]  M. Taubman,et al.  Mammalian EGLN genes have distinct patterns of mRNA expression and regulation. , 2002, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[16]  G. Semenza,et al.  FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. , 2001 .

[17]  S. McKnight,et al.  A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF , 2001, Science.

[18]  Michael I. Wilson,et al.  C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation , 2001, Cell.

[19]  P. Ratcliffe,et al.  Independent function of two destruction domains in hypoxia‐inducible factor‐α chains activated by prolyl hydroxylation , 2001, The EMBO journal.

[20]  J. Frydman,et al.  Review: cellular substrates of the eukaryotic chaperonin TRiC/CCT. , 2001, Journal of structural biology.

[21]  R. Freeman,et al.  SM-20 Is a Novel Mitochondrial Protein That Causes Caspase-dependent Cell Death in Nerve Growth Factor-dependent Neurons* , 2001, The Journal of Biological Chemistry.

[22]  J. Frydman Folding of newly translated proteins in vivo: the role of molecular chaperones. , 2001, Annual review of biochemistry.

[23]  G. Semenza,et al.  HIF-1 and human disease: one highly involved factor. , 2000, Genes & development.

[24]  M. Lerman,et al.  Mesenchymal‐epithelial transition in the developing metanephric kidney: Gene expression study by differential display , 2000, Genesis.

[25]  V. Thulasiraman,et al.  Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC. , 1999, Molecular cell.

[26]  Robert J. Schumacher,et al.  Maturation of Human Cyclin E Requires the Function of Eukaryotic Chaperonin CCT , 1998, Molecular and Cellular Biology.

[27]  G. Farr,et al.  Chaperonin-Mediated Folding in the Eukaryotic Cytosol Proceeds through Rounds of Release of Native and Nonnative Forms , 1997, Cell.

[28]  K. Gevaert,et al.  Peptides adsorbed on reverse‐phase chromatographic beads as targets for femtomole sequencing by post‐source decay matrix assisted laser desorption ionization‐reflectron time of flight mass spectrometry (MALDI‐RETOF‐MS) , 1997, Electrophoresis.

[29]  S. Madden,et al.  Induction of cell growth regulatory genes by p53. , 1996, Cancer research.

[30]  M. Gossen,et al.  Transcriptional activation by tetracyclines in mammalian cells. , 1995, Science.

[31]  U. Deuschle,et al.  Tetracycline-reversible silencing of eukaryotic promoters , 1995, Molecular and cellular biology.

[32]  M. Taubman,et al.  Identification of a novel growth factor-responsive gene in vascular smooth muscle cells. , 1994, The Journal of biological chemistry.