Amphiregulin induces CCN2 and fibronectin expression by TGF-β through EGFR-dependent pathway in lung epithelial cells

[1]  D. Ribatti,et al.  ADAM 17 and Epithelial-to-Mesenchymal Transition: The Evolving Story and Its Link to Fibrosis and Cancer , 2021, Journal of clinical medicine.

[2]  K. Chung,et al.  Abnormal ADAM17 expression causes airway fibrosis in chronic obstructive asthma. , 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[3]  Chien-Huang Lin,et al.  Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway , 2021, Molecular medicine.

[4]  G. Dou,et al.  Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway , 2021, Molecular medicine reports.

[5]  Chien-Huang Lin,et al.  TGF-β Induced CTGF Expression in Human Lung Epithelial Cells through ERK, ADAM17, RSK1, and C/EBPβ Pathways , 2020, International journal of molecular sciences.

[6]  T. Homma,et al.  Airway Epithelial Dysfunction in Asthma: Relevant to Epidermal Growth Factor Receptors and Airway Epithelial Cells , 2020, Journal of clinical medicine.

[7]  R. Hamoudi,et al.  Blood and Salivary Amphiregulin Levels as Biomarkers for Asthma , 2020, Frontiers in Medicine.

[8]  Eun Sug Park,et al.  Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 , 2020, Lancet.

[9]  M. Stauch,et al.  Amphiregulin Expression Is a Predictive Biomarker for EGFR Inhibition in Metastatic Colorectal Cancer: Combined Analysis of Three Randomized Trials , 2020, Clinical Cancer Research.

[10]  K. Dua,et al.  SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis , 2020, Respiratory Research.

[11]  V. Thannickal,et al.  Airway Remodeling in Asthma , 2020, Frontiers in Medicine.

[12]  Y. Nishimura,et al.  Group 2 Innate Lymphoid Cells and the House Dust Mite-Induced Asthma Mouse Model , 2020, Cells.

[13]  E. Schadt,et al.  Integrative study of the upper and lower airway microbiome and transcriptome in asthma. , 2020, JCI insight.

[14]  armen Berasaina,et al.  Amphiregulin , 2020, Definitions.

[15]  C Venter,et al.  Rapid quantification of cellular proliferation and migration using ImageJ. , 2019, BioTechniques.

[16]  Y. Okamoto,et al.  Amphiregulin‐Producing Pathogenic Memory T Helper 2 Cells Instruct Eosinophils to Secrete Osteopontin and Facilitate Airway Fibrosis , 2018, Immunity.

[17]  Xianlong Zhou,et al.  Thalidomide Inhibits TGF-β1-induced Epithelial to Mesenchymal Transition in Alveolar Epithelial Cells via Smad-Dependent and Smad-Independent Signaling Pathways , 2017, Scientific Reports.

[18]  Chien-Huang Lin,et al.  Correction: Induction of Connective Tissue Growth Factor Expression by Hypoxia in Human Lung Fibroblasts via the MEKK1/MEK1/ERK1/GLI-1/GLI-2 and AP-1 Pathways , 2017, PloS one.

[19]  Yong Zhang,et al.  TGF-β1 Induces EMT in Bovine Mammary Epithelial Cells Through the TGFβ1/Smad Signaling Pathway , 2017, Cellular Physiology and Biochemistry.

[20]  Qiang Xu,et al.  Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation , 2016, Oncotarget.

[21]  Xiao Yu,et al.  ADAM17 and EGFR regulate IL‐6 receptor and amphiregulin mRNA expression and release in cigarette smoke‐exposed primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD) , 2016, Physiological reports.

[22]  M. Kuo,et al.  C‐Jun N‐terminal kinase signalling pathway in response to cisplatin , 2016, Journal of cellular and molecular medicine.

[23]  Yuehua Wu,et al.  The activation of p38 MAPK limits the abnormal proliferation of vascular smooth muscle cells induced by high sodium concentrations , 2015, International journal of molecular medicine.

[24]  D. Artis,et al.  IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin–EGFR interactions , 2015, Proceedings of the National Academy of Sciences.

[25]  P. Song,et al.  β-catenin induces A549 alveolar epithelial cell mesenchymal transition during pulmonary fibrosis. , 2015, Molecular medicine reports.

[26]  W. Gause,et al.  Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair. , 2015, Immunity.

[27]  Shaoyi Chen,et al.  Integrin-linked kinase mediates CTGF-induced epithelial to mesenchymal transition in alveolar type II epithelial cells , 2015, Pediatric Research.

[28]  A. Chalaris,et al.  Senescence‐associated release of transmembrane proteins involves proteolytic processing by ADAM17 and microvesicle shedding , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[29]  Won-Kyung Cho,et al.  Modifiers of TGF-β1 effector function as novel therapeutic targets of pulmonary fibrosis , 2014, The Korean journal of internal medicine.

[30]  I. Shin,et al.  Bangpungtongseong-san, a traditional herbal medicine, attenuates chronic asthmatic effects induced by repeated ovalbumin challenge. , 2014, International journal of molecular medicine.

[31]  Chien-Huang Lin,et al.  Connective tissue growth factor induces collagen I expression in human lung fibroblasts through the Rac1/MLK3/JNK/AP-1 pathway. , 2013, Biochimica et biophysica acta.

[32]  D. Abraham,et al.  Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro , 2013, Journal of Cell Science.

[33]  Han-Oh Park,et al.  Amphiregulin, an Epidermal Growth Factor Receptor Ligand, Plays an Essential Role in the Pathogenesis of Transforming Growth Factor-β-induced Pulmonary Fibrosis , 2012, The Journal of Biological Chemistry.

[34]  K. Lipson,et al.  CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis , 2012, Fibrogenesis & tissue repair.

[35]  Q. Hamid,et al.  Remodeling in asthma. , 2011, The Journal of allergy and clinical immunology.

[36]  Q. Hamid,et al.  Amphiregulin Expression Correlates With Asthma Severity In Human Bronchial Epithelial Cells And Is Released By Histamine , 2011, ATS 2011.

[37]  Xiaobo Fan,et al.  A novel single‐chain‐Fv antibody against connective tissue growth factor attenuates bleomycin‐induced pulmonary fibrosis in mice , 2011, Respirology.

[38]  Y. Okayama,et al.  Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack. , 2009, The Journal of allergy and clinical immunology.

[39]  B. Choi,et al.  Relationship between amphiregulin and airway inflammation in children with asthma and eosinophilic bronchitis. , 2009, Chest.

[40]  E. Neilson,et al.  Biomarkers for epithelial-mesenchymal transitions. , 2009, The Journal of clinical investigation.

[41]  Samy Lamouille,et al.  TGF-β-induced epithelial to mesenchymal transition , 2009, Cell Research.

[42]  J. Prieto,et al.  The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis , 2008, Hepatology.

[43]  J. Cavaillon,et al.  Neutrophils in Cystic Fibrosis Display a Distinct Gene Expression Pattern , 2008, Molecular medicine.

[44]  Zigang Dong,et al.  The functional contrariety of JNK , 2007, Molecular carcinogenesis.

[45]  Kazuhiro Nakamura,et al.  The c-jun kinase/stress-activated pathway: regulation, function and role in human disease. , 2007, Biochimica et biophysica acta.

[46]  K. Yamauchi,et al.  Airway Remodeling in Asthma and Irreversible Airflow Limitation -ECM Deposition in Airway and Possible Therapy for Remodeling. , 2007, Allergology international : official journal of the Japanese Society of Allergology.

[47]  D. Sheppard,et al.  Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix , 2006, Proceedings of the National Academy of Sciences.

[48]  N. Altorki,et al.  Tobacco smoke stimulates the transcription of amphiregulin in human oral epithelial cells: evidence of a cyclic AMP-responsive element binding protein-dependent mechanism. , 2005, Cancer research.

[49]  C. Heldin,et al.  TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition. , 2005, Molecular biology of the cell.

[50]  Yunliang Chen,et al.  CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin. , 2004, Molecular biology of the cell.

[51]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[52]  Ying E. Zhang,et al.  TGF‐β receptor‐activated p38 MAP kinase mediates Smad‐independent TGF‐β responses , 2002 .

[53]  P. Howarth,et al.  Involvement of the epidermal growth factor receptor in epithelial repair in asthma , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[54]  J. Massagué,et al.  Transcriptional control by the TGF‐β/Smad signaling system , 2000 .